Hartil Amlo capsules 10mg/5mg №10×3

Hartil Amlo Capsules 10mg/5mg №10×3: Effective Blood Pressure Management

Description:

Hartil Amlo capsules contain ramipril and amlodipine, two powerful medications that work together to effectively lower blood pressure. These capsules are specifically formulated for patients who benefit from a combination therapy approach.

How Hartil Amlo Works:

• Ramipril: This ACE inhibitor helps reduce the production of substances that constrict blood vessels, promoting relaxation and dilation.
• Amlodipine: As a calcium channel blocker, amlodipine further relaxes blood vessels, improving blood flow and reducing strain on the heart.

Indications for Use:

Hartil Amlo is indicated for the treatment of hypertension (high blood pressure) in adults who require both ramipril and amlodipine to effectively manage their condition. This combination therapy is particularly beneficial for patients who have achieved adequate control with the individual medications taken simultaneously in the same doses.

Dosage and Administration:

Always take Hartil Amlo as directed by your doctor. The usual starting dose is one capsule, with the specific dosage determined by your healthcare provider.

• Dosage Adjustment: Your doctor may adjust your dose based on your individual response to treatment.
• Maximum Dose: The maximum dose is one capsule containing 10mg/10mg, taken once a day.

Important Considerations:

• Liver and Kidney Disease: Dosage adjustments may be necessary for patients with liver or kidney disease.
• Elderly Patients: Your doctor will likely start with a lower dose and adjust it gradually.
• Children and Adolescents: Hartil Amlo is not recommended for children and adolescents under 18 years of age, as its safety and efficacy in this population have not been established.

If You Forget to Take Hartil Amlo:

Do not take a double dose to make up for a missed dose. Simply take your next dose at the usual time.

Do Not Stop Taking Hartil Amlo:

Always discuss any changes to your medication with your doctor before discontinuing or altering your dosage.

How to Take Hartil Amlo:

• Swallow the capsules whole with liquid.
• Do not crush or chew the capsules.
• Do not take Hartil Amlo with grapefruit juice.

Pregnancy and Lactation:

• Pregnancy: Hartil Amlo should not be taken during the first 12 weeks of pregnancy. It is contraindicated after the 13th week due to potential risks to the developing fetus.
• Breastfeeding: Taking Hartil Amlo during breastfeeding is not recommended.

Precautions:

Talk to your doctor or pharmacist before taking Hartil Amlo if:

• You are elderly.
• You have heart, liver, or kidney problems.
• You have recently experienced a hypertensive crisis.
• You have a disturbed water-salt balance (dehydration).
• You are undergoing desensitization treatment for allergies.
• You are scheduled for surgery or dental procedures.
• You have high potassium levels in your blood.
• You are taking medications that cause low sodium levels.
• You are taking mTOR inhibitors or vildagliptin.
• You have collagen diseases.
• You are taking certain other blood pressure medications (ARBs, aliskiren).

Interactions with Other Drugs:

Inform your doctor or pharmacist about all medications you are taking, including over-the-counter medicines and herbal remedies.

Hartil Amlo may affect other medications, and vice versa. Specifically, tell your doctor if you are taking:

• Non-steroidal anti-inflammatory drugs (NSAIDs).
• Medications for low blood pressure.
• Rifampicin.
• St. John’s Wort.

Hartil Amlo may increase the risk of side effects when taken with:

• NSAIDs.
• Medications for cancer treatment (chemotherapy).
• Immunosuppressants (cyclosporine).
• Diuretics.
• Medications that increase potassium levels.
• Steroidal anti-inflammatory drugs.
• Allopurinol.
• Procainamide.
• mTOR inhibitors (temsirolimus, sirolimus, everolimus).
• Vildagliptin.
• Ketoconazole, itraconazole.
• Erythromycin, clarithromycin.
• Ritonavir, indinavir, nelfinavir.
• Verapamil, diltiazem.
• Trimethoprim and cotrimoxazole.
• Tacrolimus.
• ARBs or aliskiren.

Hartil Amlo may affect the following medications:

• Medications for diabetes (insulin, oral glucose-lowering agents).
• Lithium preparations.
• Cyclosporine.
• Simvastatin.

Food and Drink:

• Alcohol: Drinking alcohol while taking Hartil Amlo can increase feelings of dizziness and uncertainty.
• Grapefruit: Grapefruit and grapefruit juice should be avoided, as they can increase amlodipine levels in the blood, potentially leading to unpredictable drops in blood pressure.

Contraindications:

Do not take Hartil Amlo if you:

• Are allergic to ramipril, amlodipine, other calcium channel blockers, ACE inhibitors, or any excipients in Hartil Amlo.
• Have severe vasoconstriction preventing blood outflow from the left ventricle.
• Have cardiogenic shock.
• Have a history of severe allergic reaction (angioedema).
• Are undergoing dialysis or blood filtration.
• Have kidney disease with reduced blood flow to the kidneys (renal artery stenosis).
• Have abnormally low or unstable blood pressure.
• Have heart failure after a myocardial infarction.
• Are in the second or third trimester of pregnancy.
• Have diabetes, impaired kidney function, or are taking blood pressure medications containing aliskiren.

Side Effects:

Hartil Amlo, like all medications, can cause side effects. If you experience any serious side effects, stop taking Hartil Amlo and seek immediate medical attention.

Common side effects include:

• Drowsiness.
• Strong heartbeat.
• Facial flushing.
• Headache.
• Fatigue.
• Dizziness.
• Visual impairment.
• Diarrhea or constipation.
• Fainting.
• Hypotension (low blood pressure).
• Dry cough.
• Sinusitis or bronchitis.
• Shortness of breath.
• Abdominal pain.
• Nausea and vomiting.
• Skin rash.
• Chest pain.
• Muscle cramps or pain.
• Elevated potassium levels.

Uncommon side effects include:

• Mood changes.
• Insomnia.
• Shivering.
• Ringing in the ears.
• Rhinitis (runny nose).
• Hair loss.
• Itching.
• Increased urination.
• Kidney function impairment.
• Pain.
• Backache.
• Weight gain or loss.
• Gynecomastia (breast enlargement in men).
• Vertigo.
• Paresthesia (unusual skin sensations).
• Hypesthesia (loss of skin sensation).
• Taste changes.
• Sleep disorders.
• Depression, anxiety, nervousness, agitation.
• Nasal congestion.
• Asthma exacerbation.
• Intestinal angioedema (abdominal pain, vomiting, diarrhea).
• Heartburn.
• Dry mouth.
• Gastritis.
• Increased sweating.
• Anorexia.
• Increased heart rate, slow heart rate, or arrhythmia.
• Hand and foot swelling.
• Blurred vision.
• Joint pain.
• Fever.
• Sexual dysfunction.
• Eosinophilia (increased eosinophils in blood).
• Liver, pancreas, and kidney function changes.
• Myocardial infarction.

Rare side effects include:

• Confusion.
• Redness and swelling of the tongue.
• Skin peeling and itching.
• Nail disease.
• Skin rash or bruising.
• Spots on the skin or cold extremities.
• Red, itchy, swollen, or watery eyes.
• Hearing disorders.
• Decreased red blood cells, white blood cells, and platelets.
• Decreased hemoglobin levels.

Very Rare side effects include:

• High blood sugar.
• Pancreatitis.
• Hepatitis.
• Photosensitivity.
• Gingival hyperplasia.
• Muscle stiffness, tremors, or impaired movement.
• Increased muscle tone.
• Vasculitis (inflammation of blood vessels).

Other side effects (frequency unknown):

• Concentration impairment.
• Mouth swelling.
• Oral mucosal inflammation.
• Decreased blood cells.
• Hyponatremia (low sodium levels).
• Raynaud’s syndrome.
• Slowed or impaired psychomotor reactions.
• Burning sensation.
• Impaired sense of smell.
• Psoriasis.
• Increased antinuclear antibodies.
• Syndrome of inappropriate antidiuretic hormone secretion (concentrated urine, muscle spasms, feeling unwell, seizures).
• Tremors, rigid posture, mask-like face, slow movements, shuffling gait.

Storage Conditions:

Store Hartil Amlo at a temperature not exceeding 30°C, out of the reach of children.

Disclaimer:

This information is not a substitute for medical advice. Always consult your doctor or pharmacist for personalized guidance regarding Hartil Amlo.