Furazolidone tablets 50mg №10×2

Furazolidone Tablets 50mg: Effective Treatment for Bacterial and Protozoal Infections

Furazolidone 50mg tablets are a powerful antimicrobial and antiprotozoal medication used to treat a variety of infections caused by susceptible microorganisms. This comprehensive guide provides detailed information on Furazolidone, including its uses, dosages, side effects, and precautions.

What is Furazolidone?

Furazolidone is a broad-spectrum antibiotic that works by disrupting the activity of certain enzyme systems in bacteria, effectively inhibiting their growth. This makes it effective against a wide range of bacteria, including:

• Gram-positive cocci: Streptococcus, Staphylococcus
• Gram-negative rods: Escherichia, Salmonella, Shigella, Proteus, Klebsiella, Enterobacter
• Protozoa: Lamblia

Uses of Furazolidone Tablets:

Furazolidone tablets are primarily prescribed for the treatment of:

• Dysentery: Infections of the intestines caused by Shigella bacteria.
• Paratyphoid fever: A bacterial infection that causes fever, abdominal pain, and diarrhea.
• Food poisoning: Bacterial infections contracted through contaminated food.
• Giardiasis: A parasitic infection of the small intestine caused by Giardia lamblia.

How to Take Furazolidone:

Furazolidone tablets should be taken orally after a meal with plenty of liquid. The dosage and duration of treatment will vary depending on the type of infection and the individual’s age and health.

Dosage:

• Adults: 2-3 tablets (100-150mg) 4 times daily, but not exceeding 800mg per day, for 5-10 days.
• Children over 8 years: 6-7mg/kg of body weight per day divided into 4 doses.

Duration:

The duration of treatment depends on the severity of the infection and the effectiveness of the medication.

Important Precautions:

• Pregnancy and Lactation: Furazolidone is contraindicated during pregnancy. Breastfeeding should be stopped while taking this medication.
• Liver and Kidney Function: Use with caution in individuals with impaired liver or kidney function.
• Peripheral Neuropathies: The risk of peripheral neuropathies may be increased in patients with anemia, diabetes mellitus, electrolyte imbalance, or hypovitaminosis B.
• MAO Inhibition: Furazolidone is a monoamine oxidase inhibitor (MAOI) and should be used with caution. Avoid foods rich in tyramine (cheese, chocolate, smoked meats) and medications that interact with MAOIs.
• Alcohol: Do not consume alcohol during Furazolidone therapy and for 4 days after stopping the medication.
• Children Under 8 Years: This dosage form of Furazolidone is not suitable for children under 8 years of age.

Potential Side Effects:

Like most medications, Furazolidone may cause side effects, although not everyone experiences them. Common side effects include:

• Gastrointestinal: Abdominal pain, nausea, vomiting, diarrhea, anorexia, cholestasis.
• Central Nervous System: Headache, dizziness, peripheral neuropathy.
• Blood System: Rarely, leukopenia, agranulocytosis, hemolysis (in individuals with glucose-6-phosphate dehydrogenase deficiency).
• Allergic Reactions: Pruritus, urticaria, rash (including maculopapular).
• Other: Hypoglycemia, orthostatic hypotension, dark yellow urine, fever, weakness.

Interactions with Other Medications:

• Monoamine Oxidase Inhibitors (MAOIs): Risk of hypertensive crisis.
• Sympathomimetics: Risk of hypertensive crisis.
• Tricyclic Antidepressants: Risk of hypertensive crisis.
• Chloramphenicol and Ristomycin: Increased risk of hematopoiesis suppression.
• Aminoglycosides and Tetracycline: Enhanced antimicrobial effect.
• Urine Alkalizing Agents: Reduced Furazolidone effect.
• Urine Acidifying Agents: Increased Furazolidone effect.

Contraindications:

Furazolidone is contraindicated in the following cases:

• End-stage chronic renal failure
• Liver dysfunction
• Deficiency of glucose-6-phosphate dehydrogenase
• Pregnancy
• Lactation
• Children under 8 years of age
• Increased individual sensitivity to the components of the drug and nitrofurans

Storage:

Store Furazolidone tablets in a cool, dry place, protected from light and moisture, at a temperature not exceeding 25°C. Keep out of the reach of children.

Buy Furazolidone Tablets 50mg No. 10×2:

For information on purchasing Furazolidone tablets 50mg No. 10×2, please consult your local pharmacy or healthcare provider.

Important Note:

This information is for general knowledge and informational purposes only, and does not constitute medical advice. Always consult with your healthcare provider before starting any new medication or treatment. They can provide personalized advice and ensure the safe and effective use of Furazolidone tablets for your specific condition.