Phosphalite for Kidney Stones: 120 Capsules, 480mg

Title: Phosphalit: 120 Capsules, 480mg – For Phosphate Kidney Stones

Description:

Phosphalit is a unique blend of bioactive ingredients designed to support kidney health and help prevent the formation of phosphate kidney stones. Its formula, backed by scientific research, combines berberine from Bergenia ligulata, calcium carbonate, nicotinamide (vitamin B3), and cranberry extract, each contributing to a multifaceted approach to managing phosphate stones. Berberine significantly reduces the growth rate of calcium phosphate crystals and increases magnesium excretion, a key anti-lithogenic mineral. Calcium carbonate effectively lowers blood phosphate levels. Nicotinamide further reduces phosphate levels through inhibiting phosphate transport in the kidneys and intestines. Cranberry extract increases urine acidity, inhibiting phosphate stone formation, and provides additional antimicrobial and antioxidant benefits. Consult your doctor before use. 120 capsules, 480mg total.

Enhanced Product Description:

Phosphalit offers a comprehensive, scientifically-backed approach to supporting kidney health and preventing phosphate kidney stones. This powerful formula combines four key ingredients, each meticulously chosen for its proven effectiveness:

• Bergenia Ligulata Extract (Berberine): Studies demonstrate berberine’s ability to significantly reduce the growth rate of calcium phosphate crystals in urine [1, 2], increase urinary magnesium excretion (a crucial anti-lithogenic mineral) [3], and mitigate kidney cell damage associated with kidney stone formation [4]. Its diuretic properties further support the management of phosphate stones [5].
• Calcium Carbonate: A clinically proven mineral, calcium carbonate effectively reduces blood phosphate levels. Studies show a 21% reduction in phosphate levels after just two months of use [6], with sustained normalization achievable over 24 months [7].
• Nicotinamide (Vitamin B3): This essential B vitamin effectively lowers blood phosphate levels by inhibiting phosphate transport in both the kidneys and intestines [8, 9, 10]. Studies show reductions of 10.9%, 21%, and 39% after 2, 8, and 32 weeks respectively [8, 9]. Nicotinamide’s excellent tolerability and cost-effectiveness make it an ideal component in phosphate management [8].
• Cranberry Extract: Long utilized in urology for its antimicrobial properties, cranberry extract also helps to increase urine acidity (pH 4.5-6.5) [11], inhibiting the formation of phosphate stones. It also reduces urinary uric acid levels [12], and offers additional antioxidant protection [13].

Contraindications:

Individual intolerance to components, pregnancy, and breastfeeding.

Special Instructions:

Consult a doctor before use.

Recommended Usage:

Adults take 1 capsule twice daily with meals. Course duration: 1 month. The course can be repeated if necessary.

Storage:

Store in a place inaccessible to children, at a temperature not exceeding +25°C.

Shelf Life:

2 years.

Literature Cited:

1. V. S. Joshi et al. Journal of Crystal Growth, Feb. 2005, vol. 275, no. 1–2
2. Joshi VS, et al. Urol Res. 2005 May; 33(2):80-6
3. H. G. Tiselius, BJU Int., vol. 91, no. 8, pp. 758–767, May 2003
4. A. Singh et al. J. Ethnopharmacol., vol. 275, p. 114104, Jul. 2021
5. Singh N., et al. J. Pharm. Res. 2009; 2:958–960
6. Miller D, et al. ASAIO Trans. 1989 Jul-Sep; 35(3):322-4
7. Malberti et al 1988. Am J of Kidney Diseases, 1988 12(6), 487–491
8. Restrepo Valencia CA et al. Nefrologia. 2008; 28(1):61-69.
9. Rennick A et al. Pharmacotherapy, 2013; 33(6):683–690
10. A. Lenglet, S.et al. Drugs in R and D, vol. 13, no. 3
11. R. Raz, Clinical Infectious Diseases, vol. 38, no. 10
12. M. T. Gettman, J. Urol., vol. 174, no. 2, pp. 590–594, 2005
13. A. Ledda et al., Eur. Rev. Med. Pharmacol. Sci., pp. 77–80, 2015