Nise 100mg Tablets: Effective Pain Relief & Anti-Inflammatory Solution
Description:
Nise 100mg tablets are a powerful non-steroidal anti-inflammatory drug (NSAID) used for effectively managing pain and inflammation. Each round, smooth, and slightly yellow tablet contains 100mg of nimesulide, the active ingredient.
Packaging:
Nise tablets are packaged in blister packs of 10 tablets each. Each box contains two blister packs, ensuring a convenient and safe storage.
How It Works:
Nimesulide, the key ingredient in Nise tablets, works by inhibiting the production of prostaglandins. These substances are responsible for inflammation, pain, and fever. By blocking their synthesis, Nise helps to reduce these symptoms.
Pharmacokinetics:
Nimesulide is rapidly absorbed when taken orally. Peak plasma levels are typically reached within 2 to 3 hours after a single 100mg dose. The drug is extensively metabolized in the liver and excreted primarily in the urine.
Indications for Use:
- Acute pain: Nise effectively manages acute pain associated with various conditions.
- Primary dysmenorrhea: Nise can provide relief from menstrual cramps.
Important Note:
Nise should be used as a second-line treatment option only. Always consult with a healthcare professional before using Nise, especially if you have any pre-existing medical conditions.
Dosage and Administration:
The recommended dosage for adults is 100mg twice daily, taken after meals. For elderly patients, there is no need for dose adjustment.
Important Considerations:
- Children and adolescents (under 18 years): Nise is not recommended for use in children or adolescents.
- Patients with impaired renal function: Dose adjustment may be necessary for patients with mild to moderate renal insufficiency. Nise is contraindicated in patients with severe renal insufficiency.
- Patients with hepatic impairment: Nise is contraindicated in patients with liver impairment.
- Pregnancy and Lactation: Nise is contraindicated during the third trimester of pregnancy and lactation. It is also not recommended for use in women planning pregnancy.
Side Effects:
As with all medications, Nise can cause side effects. The most common side effects include diarrhea, nausea, vomiting, and abdominal pain.
Precautions:
- Gastrointestinal disorders: Nise should be used with caution in patients with a history of gastrointestinal bleeding, ulcers, or other gastrointestinal problems.
- Renal and cardiac insufficiency: Nise should be used with caution in patients with renal or cardiac insufficiency.
- Skin reactions: Rare cases of severe skin reactions, including exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been reported. If you experience a rash or other skin reaction, discontinue use and consult a healthcare professional immediately.
- Cardiovascular disorders: Nise should be used with caution in patients with a history of heart disease or stroke.
Drug Interactions:
Nise may interact with other medications. It is essential to inform your healthcare provider about all medications you are currently taking, including over-the-counter medications and herbal supplements.
Overdose:
In case of overdose, contact your healthcare provider or poison control center immediately.
Storage:
Store Nise tablets at room temperature in a dry place, protected from light and moisture. Keep out of reach of children.
Disclaimer:
This information is for educational purposes only and should not be considered medical advice. Always consult with a healthcare professional before starting any new medication.