Hemos-PFS Spiral Plasma Filter with Hemos-MN.PF Bloodline

The Hemos-PFS spiral plasma filter, in conjunction with the Hemos-MN.PF bloodline, represents a significant advancement in plasmapheresis technology. This innovative device, protected by patents RU 2514545, 2491100, and 89131, utilizes a novel spiral membrane design—a world first—offering substantial improvements over previous flat-sheet and hollow-fiber filters.

Superior Performance and Efficiency

The Hemos-PFS is the cornerstone of efficient therapeutic and donor plasmapheresis, expertly extracting plasma from blood. Its unique design also allows for a gentler, more efficient method of washing cryopreserved erythrocytes, resulting in a higher yield of viable red blood cells for transfusion.

Compared to domestic flat-sheet plasma filters (PFM-800/500, PFM 01-TT (“Rosa”)) and imported hollow-fiber filters, the Hemos-PFS boasts several key advantages:

• Compact and Lightweight: Significantly reduced weight, size, and blood volume.
• Enhanced Biocompatibility: Features a highly porous, hydrophylized membrane with superior hemocompatibility and low affinity for plasma proteins and lipids.
• High Filtration Speed: Achieves a high filtration rate of 15-25 ml/min.
• Extended Operational Life: Operates for 3-5 hours, maintaining performance across a wide range of blood perfusion speeds (30-120 ml/min) and high transmembrane pressures (up to 250-280 mmHg) and impulse pressure (<3 sec) up to 400 mmHg. Minimal performance degradation (less than 8%) over extended use, eliminating the need for mid-procedure rinsing.
• Versatile Compatibility: Compatible with all major domestic (“Hemos-PF,” “Hemofenix,” “Gemma”) and international (Multifiltrate, PrismaFlex, Octo-Nova, Fresenius 4008, 5008, Innova Hospal, Aquarius, “Hemofer-1,” etc.) membrane plasmapheresis machines. Utilizes standard Luer-Lock connections for ease of use.
• Simplified Operation: Air expulsion and initial saline filling are straightforward, unlike with domestic filters (PFM-800/500, PFM 01-TT (“Rosa”)), eliminating the need for tilting or shaking due to the optimal placement of blood and plasma ports.

Applications and Equivalency

The Hemos-PFS is available as a standalone unit or as part of the pre-assembled “Plasmoset” disposable kit for the Hemos-PF plasmapheresis machine. It provides a superior equivalent to imported hollow-fiber filters such as TPE (PF)-1000/2000, 3M PlasCure 03, Haemoselect, and others, as well as domestic flat-sheet filters PFM-800/500, PFM-01-TT (“Rosa”).

Regulatory Approval and Availability

The Hemos-PFS spiral plasma filter is approved for medical use by Roszdravnadzor (RU No. RZN 2013/713, dated July 16, 2013) and is currently in mass production.

Developer, Manufacturer, and Supplier

NII “Biotech-M”

Keywords

Hemos-PFS, plasma filter, spiral plasma filter, plasmapheresis, blood filter, membrane filter, erythrocyte washing, medical device, Biotech-M, PFM-800/500, PFM 01-TT, TPE (PF)-1000/2000, 3M PlasCure 03, Haemoselect, blood purification, hemos-mn.pf, medical technology, disposable kit, plasmoset, high filtration rate, biocompatible, heparin, sodium citrate.