Enalapril Pharmland tablets 10mg №10×3

Enalapril is generally well tolerated and in most cases does not cause adverse reactions requiring discontinuation of the drug. From the side of the cardiovascular system: less than 2% – arterial hypotension, orthostatic hypotension, fainting; in some cases – myocardial infarction, stroke, possibly secondary to severe arterial hypotension in patients at high risk, chest pain, palpitations, cardiac arrhythmias, angina pectoris, Raynaud's syndrome. From the side of the central nervous system and peripheral nervous system: most often – dizziness, headache; in 2-3% of cases – increased fatigue, asthenia; in some cases – depression, confusion, drowsiness, insomnia, irritability, sleep disturbances, paresthesia, tinnitus, blurred vision. From the digestive system: less than 2% – nausea, diarrhea; in some cases – intestinal obstruction, pancreatitis, liver failure, hepatitis (hepatocellular or cholestatic), jaundice, abdominal pain, vomiting, dyspepsia, constipation, anorexia, stomatitis, taste disturbance, glossitis, increased activity of hepatic transaminases and plasma bilirubin concentration (These changes are usually reversible and normalize after discontinuation of enalapril). From the respiratory system: less than 2% – cough; in some cases – pulmonary infiltrates, bronchospasm, bronchial asthma, shortness of breath, rhinorrhea, sore throat, hoarseness. From the urinary system: rarely – impaired renal function, renal failure, oliguria, increased urea, creatinine (these changes are usually reversible and normalize after stopping enalapril). Allergic reactions: less than 2% – skin rash; rarely – angioedema of the face, limbs, lips, tongue, glottis and / or larynx; in some cases – erythema multiforme, exfoliative dermatitis, Steven-Johnson syndrome, toxic epidermal necrolysis, urticaria. A complex symptom complex has been reported, which may include all or some of the following symptoms: fever, serositis, vasculitis, myalgia/myositis, arthralgia/arthritis, positive antinuclear antibody test, elevated ESR, eosinophilia, and leukocytosis. On the part of the hematopoietic system: a decrease in hemoglobin and hematocrit levels is possible; in some cases – neutropenia, thrombocytopenia, agranulocytosis. Dermatological reactions: in some cases – increased sweating, pemphigus, itching, rash, alopecia, photosensitivity, redness of the skin of the face. On the part of laboratory parameters: the development of hyperkalemia and hyponatremia is possible. Others: less than 2% – muscle cramps; in some cases – impotence. In general, enalapril is well tolerated. The overall frequency of side effects when using Enalapril does not exceed that when prescribing placebo. In most cases, side effects are minor, temporary and do not require discontinuation of therapy.