Chlorhexidine bigluconate solution 0.5mg/ml 100ml

Name:
Chlorhexidine bigluconate.
Description:
Transparent, colorless or slightly yellowish liquid, odorless. The main active ingredient Release formSolution for external use. Dosage 0.05% 100 ml. Pharmacological action An antiseptic agent with a pronounced bactericidal effect against gram-positive and gram-negative bacteria (does not affect the acid-resistant forms of the latter): Treponema pallidum, Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis, protozoa (Trichomonas vaginalis), microbial spores, viruses, fungi; slightly affects some types of Proteus and Pseudomonas. Chlorhexidine bigluconate is also active against treponema, gonococci, Trichomonas. Retains activity (somewhat reduced) in the presence of blood, pus. Cleanses and disinfects the skin without causing damage. Indications for use The drug is used for the prevention of sexually transmitted diseases (syphilis, gonorrhea, trichomoniasis, chlamydia, etc.). It is used for antiseptic treatment of wounds, abrasions and cracks, burns, for bacterial and fungal diseases of the skin and mucous membranes, incl. in urology, surgery, obstetrics and gynecology. In dentistry, it is used for rinsing the mouth in cases where it is difficult to comply with hygiene rules, in the postoperative period after periodontal flap surgery, for washing periodontal pockets, fistulas, and abscess cavities. Since chlorhexidine bigluconate has a cytotoxic effect, the concentration of the rinse solution should not exceed 0.25 mg / ml. Method of administration and doses The drug is used in the form of irrigations, rinses and applications – 5-10 ml of the solution is applied to the affected surface of the skin or mucous membranes with an exposure of 1-3 minutes 2-3 times a day (on a swab or by irrigation). For the prevention of sexually transmitted diseases, the drug is effective if applied no later than 2 hours after sexual intercourse. It is used after urination: using a nozzle, insert into the urethra for men (2-3 ml), for women into the urethra (1-2 ml) and into the vagina (5-10 ml) and hold for 2-3 minutes. Treat the skin of the inner surfaces of the thighs, pubis, genitals. After the procedure, it is not recommended to urinate for 2 hours. Complex treatment of urethritis and urethroprostatitis is carried out by injecting 2-3 ml of the drug into the urethra 1-2 times a day, the course is 10 days, the procedures are prescribed every other day. The solution for rinsing is usually prescribed 2-3 times a day (for rinsing the mouth, the drug should be mixed with an equal amount of water). Use during pregnancy and lactation Use with caution in pregnant and lactating women due to the lack of data on clinical experience. Do not treat the surface of the mammary glands before feeding. PrecautionsThe bactericidal effect increases with increasing temperature. At temperatures above 100 °C, the drug is partially decomposed. Exposure of hypochlorite bleaches to fabrics that have previously been in contact with preparations containing chlorhexidine may contribute to the appearance of brown spots on them. In patients with open traumatic brain injury, spinal cord injury, perforation of the tympanic membrane, contact with the surface of the brain, meninges and the cavity of the inner ear should be avoided. In case of contact with the mucous membranes of the eye, they should be rinsed quickly and thoroughly with water. Simultaneous use with iodine is not recommended. Application in children. The use of chlorhexidine solution (water or alcohol) in newborns as a skin antiseptic before invasive procedures is associated with a certain risk of chemical burns. Based on spontaneous reporting and literature data, a higher risk of skin reactions has been identified in preterm infants, especially those born before 32 weeks of gestation, in whom chlorhexidine was used during the first two weeks of life. Before carrying out invasive procedures, it is necessary to remove all materials moistened with chlorhexidine: bandages, sheets, napkins, gowns, etc. Do not use an excessive amount of solution. Do not allow the solution to accumulate in skin folds, under the patient’s body, on materials that are in direct contact with the child’s skin. If an airtight dressing (occlusive dressing) is to be applied to skin previously exposed to chlorhexidine, ensure that there is no excess chlorhexidine solution on the skin before applying the dressing. Use in the elderly. There are no data regarding the features of use in elderly patients. Interaction with other drugs Not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose). Simultaneous use with iodine is not recommended. The presence of soap can inactivate chlorhexidine digluconate, so soap residue must be thoroughly washed off before using the drug. Ethanol enhances the effectiveness of the drug. Contraindications Hypersensitivity, dermatitis, viral skin diseases, age up to 12 years. It is not recommended to use for the treatment of wounds with a large surface. Composition A 40 ml bottle contains: active ingredient: chlorhexidine bigluconate (in the form of dezine (chlorhexidine bigluconate 20% solution)) – 20 mg; excipient: purified water – up to 40 ml. A 100 ml bottle contains: active ingredient: chlorhexidine bigluconate (in the form of dezine (chlorhexidine bigluconate 20% solution)) – 50 mg; excipient: purified water – up to 100 ml. A 200 ml bottle contains: active ingredient: chlorhexidine bigluconate (in the form of dezine (chlorhexidine bigluconate 20% solution)) – 100 mg; excipient: purified water – up to 200 ml. Overdose Cases of overdose with external use are unknown. When ingested, the drug is practically not absorbed, so systemic effects are unlikely. However, in case of accidental ingestion, gastric lavage should be carried out. If necessary, carry out symptomatic therapy. Side effects Possible allergic reactions (skin rash), dryness and itching of the skin, dermatitis, photosensitivity, stickiness of the skin of the hands (within 3-5 minutes), chemical burns of newborns (frequency unknown). In the treatment of gingivitis – staining of tooth enamel, deposition of tartar, taste disturbance. In case of adverse reactions, including those not listed in this leaflet, you should consult a doctor. Storage conditionsStore at a temperature not exceeding 25 °C. Keep out of the reach of children. Buy Chlorhexidine bigluconate solution 0.5mg/ml 100ml