Lamisil cream 1% 15g №1

Name:
Lamisil cream dnar. approx. 1% in tubes 15g per pack. No. 1
Description:
White homogeneous or almost homogeneous, glossy cream with a slight characteristic odor. The main active ingredient Terbinafine Release form cream Dosage 15 g Special instructions Lamisil cream does not affect the ability to drive a car and work with mechanisms Pharmacological action Antifungal agents for the treatment of skin diseases. Other antifungal agents for topical use. ATX code: D01AE15. Pharmacodynamics An antifungal drug for topical use with a wide spectrum of antifungal activity. In small concentrations, terbinafine has a fungicidal effect against dermatophytes (Trychophyton rubrum, T. mentagrophytes, T. verrucosum, T. violaceum, T. tonsurans, Microsporum canis, Epidermophyton floccosum), molds (mainly C. albicans) and certain dimorphic fungi ( Pityrosporum orbiculare). Activity against yeast fungi, depending on their type, can be fungicidal or fungistatic. Terbinafine specifically alters the early stage of sterol biosynthesis occurring in fungi. This leads to a deficiency of ergosterol and to intracellular accumulation of squalene, which causes the death of the fungal cell. The action of terbinafine is carried out by inhibiting the enzyme squalene epoxidase, located on the cell membrane of the fungus. Terbinafine does not affect the cytochrome P450 system in humans and, accordingly, the metabolism of hormones or other drugs. Pharmacokinetics When applied topically, absorption is less than 5%, it has a slight systemic effect. After topical application, terbinafine penetrates the skin and accumulates in the stratum corneum. After 7 days of topical application, fungicidal concentrations of terbinafine are found in the stratum corneum for another 7 days. Indications for use Fungal infections of the skin, such as ringworm of the feet (tinea pedis or “fungus” of the foot), inguinal ringworm (tinea cruris), fungal infections of the smooth skin of the body (tinea corporis), caused by dermatophytes such as Trichophyton (including T. rubrum , T. mentagrophytes, T. verrucosum, T. violaceum), Microsporum canis, Epidermophyton floccosum. Yeast infections of the skin, mainly those caused by the genus Candida (eg Candida albicans), particularly diaper rash. Pityriasis versicolor (Tinea versicolor) caused by Pityrosporum orbiculare (also known as Malasseziafurfur). Dosage and administration Externally. Adults and children over the age of 12. Before applying the cream, clean and dry the affected areas. The cream is applied once or twice a day with a thin layer on the affected skin and adjacent areas and lightly rubbed. For infections accompanied by diaper rash (under the mammary glands, in the interdigital spaces, between the buttocks, in the inguinal region), the places where the cream is applied can be covered with gauze, especially at night. Average duration of treatment Dermatomycosis of the feet (interdigital area) 1 week 1 time per day Dermatomycosis of the feet “moccasin type” 2 weeks 2 times a day Inguinal ringworm, fungal infections of the smooth skin of the body 1 week 1 time per day -2 times a day Pityriasis versicolor 2 weeks 1-2 times a day A decrease in the severity of clinical manifestations is usually noted in the first days of treatment. In case of irregular treatment or its premature termination, there is a risk of recurrence of the infection. If after one to two weeks of treatment there are no signs of improvement, you should consult a doctor. The dosing regimen of Lamisil cream in the elderly does not differ from that described above. Use of the drug in children Experience with the use of Lamisil cream in children under 12 years of age is limited. In this regard, the use of this drug in children under 12 years of age is not recommended. Use during pregnancy and lactation In experimental studies, the teratogenic properties of terbinafine have not been identified. To date, no malformations have been reported with the use of Lamisil. However, since the clinical experience with Lamisil in pregnant women is very limited, it should only be used under strict indications. Terbinafine is excreted in breast milk. Do not use Lamisil Cream while breastfeeding Precautions Lamisil Cream is for external use only. Avoid getting the cream in your eyes as it can cause irritation. In case of accidental contact of the drug with the eyes, they should be rinsed immediately with running water, and in case of persistent irritation, it is necessary to consult a doctor. Lamisil cream contains cetyl alcohol and stearyl alcohol, which may cause skin irritation at the site of application. Interactions with other drugs No drug interactions are known for Lamisil cream. Contraindications Hypersensitivity to terbinafine or to any of the inactive ingredients that make up the drug. Composition 1 g of cream contains: Active substance – 10 mg of terbinafine hydrochloride. Excipients: benzyl alcohol, sodium hydroxide, sorbitan stearate, cetyl palmitate, stearyl alcohol, cetyl alcohol, polysorbate 60, isopropyl myristate, purified water. Overdose No cases of drug overdose have been reported. If Lamisil cream is accidentally taken orally, the same side effects can be expected as with an overdose of Lamisil tablets (headache, nausea, epigastric pain and dizziness). Treatment: activated charcoal, if necessary – symptomatic supportive therapy. Side effectsRedness, itching or burning sensation, peeling of the skin, pain or irritation may appear at the sites of application of the drug, but discontinuation of treatment due to these phenomena is rarely required. These less serious side effects should be distinguished from rare allergic reactions (eg, generalized rash and / or redness, urticaria, angioedema, repeated allergic reaction), the development of which requires discontinuation of treatment. In rare cases, an exacerbation of a fungal infection is possible. In the event of an adverse event, even if it is not mentioned above, you should inform your doctor. Storage conditions 3 years. Do not use after the expiration date. Buy Lamisil cream 1% 15g №1 Price for Lamisil cream 1% 15g №1 Instructions for use for Lamisil cream 1% 15g №1