Prednisolone ointment 5mg/g 10g №1

Name:
Prednisolone ointment for narcotic application 5 mg/g in tubes 10 g in pack No. 1
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White color ointment. The main active ingredient Prednisolone Release form Ointment Dosage 5 mg / g Pharmacological action Prednisolone is a synthetic glucocorticosteroid, a drug for topical use. It has anti-inflammatory, anti-allergic, anti-edema effect. It inhibits the release of inflammatory mediators (histamine, prostaglandins, leukotrienes, lysosomal enzymes). Suppresses the skin inflammatory response, reduces vasodilation and increased vascular permeability in the focus of inflammation, reduces itching and pain at the site of application. Indications for use As part of the complex therapy of inflammatory and allergic diseases of the non-microbial skin. etiology: urticaria, eczema, allergic and seborrheic dermatitis, psoriasis, lupus erythematosus, erythroderma. Method of application and doses The ointment is applied in a thin layer on the affected areas of the skin, 1-3 times a day, gently rubbing. The duration of the course of treatment depends on the nature of the disease and the effectiveness of therapy, usually 6-14 days. Do not use the drug for longer than 14 days. It is necessary to stop treatment gradually, increasing the intervals between applications or switching to drugs that do not contain corticosteroids. Children. When prescribing the drug to children older than 1 year, the total duration of treatment should be limited to 3-7 days and measures leading to increased absorption of corticosteroids (warming, fixing and occlusive dressings, diapers) should be excluded. Use during pregnancy and lactation The drug is contraindicated in pregnant women. Nursing mothers are advised to stop breastfeeding for the period of treatment. Influence on the ability to drive a car and potentially dangerous mechanisms Studies to assess the impact on the ability to drive a car or work with machinery have not been conducted. Given the profile of adverse reactions of the drug, no effect on the speed of reaction when driving vehicles or working with other mechanisms is expected. Precautions The drug should be prescribed in the smallest dosages and in the shortest possible time necessary. to achieve the desired therapeutic effect. If there is a history of indications of psychosis, high doses are prescribed under the strict supervision of a physician. With prolonged use of the drug, abrupt cancellation is dangerous. It is possible to exacerbate the disease and worsen the general condition of the patient. Therefore, the drug should be discontinued gradually. In the process of treatment, it is necessary to control the oculist, control blood pressure. Treatment should be carried out under the supervision of a physician. In order to reduce the development of adverse reactions, corticosteroids and nonsteroidal drugs should be alternated. The maximum allowable area of skin treated with corticosteroids should not exceed 20% of the body surface. Corticosteroids should be used in short courses and only for the treatment of an exacerbation, but not for prevention. For the appointment of prednisolone, one should take into account the daily secretory rhythm of glucocorticosteroids, the rhythm of the release of hormones of the adrenal cortex: in the morning, large doses are prescribed, in the afternoon – medium, in the evening – small. In the case of use in acne vulgaris or rosacea, an exacerbation of the disease is possible. Avoid getting the drug on the mucous membrane of the organs of vision. Caution should be used in immunodeficient states (including AIDS or HIV-infected). On the skin of the face, armpit and inguinal region, the drug is recommended to be used with caution, since its absorption increases and the risk of adverse reactions increases. Do not apply the drug to areas with atrophied skin. As with other topical corticosteroids, prednisolone should not be applied to the skin around the eyes due to the risk of developing glaucoma or subcapsular cataracts. Corticosteroids may mask the symptoms of an allergic reaction to any of the components of the drug. In elderly patients, the drug should be used with caution, as they may be more sensitive to its effects due to thinning of the skin. When using glucocorticoids, the risk of secondary skin infections increases. In case of infection, it is necessary to prescribe appropriate therapy with the use of antibacterial and / or antifungal drugs. The drug should be used with caution in patients with psoriasis, since topical use of glucocorticoids can be dangerous due to the possibility of relapse of the disease, the development of tolerance, the risk of generalization of pustular psoriasis, the development of local or systemic toxicity due to impaired skin barrier function. Corticosteroids can change the appearance of some skin lesions, making the diagnosis difficult. Due to the content of parahydroxybenzoates in the composition after the use of the drug, the development of allergic reactions (including delayed ones) is possible. In children older than one year, use with caution, under the supervision of a physician. It is necessary to limit the total duration of treatment and exclude activities leading to increased resorption and absorption of the drug. Do not use for the treatment of “diaper” dermatitis. Due to the fact that in children the ratio of area to body weight is greater than in adults, children are at greater risk of suppression of the function of the pituitary-adrenal system and the development of Cushing’s syndrome when using topical corticosteroids. With prolonged use of the drug in children, it is necessary to monitor body weight, height, and plasma cortisol levels. Interaction with other drugs No drug interactions have been described with topical application of prednisolone in the form of an ointment. During the period of treatment, vaccination against smallpox or other types of immunization should not be carried out, especially with prolonged use of the drug on a large surface area of the skin. Contraindications Hypersensitivity to the components of the drug, Cushing’s syndrome, chicken pox, vaccination period, herpes simplex, wound or ulcerative lesions, bacterial or viral and fungal skin diseases, skin tuberculosis, skin manifestations of syphilis, skin tumors, acne vulgaris, rosacea, perioral dermatitis, children’s age up to 1 year, pregnancy, breastfeeding period. Ingredients Ingredients per tube active ingredient – prednisolone – 50 mg; excipients – glycerin, soft white paraffin, stearic acid, emulsifier No. 1, methyl parahydroxybenzoate, propyl parahydroxybenzoate, purified water. Overdose In case of overdose, the manifestations of adverse reactions may increase. With prolonged use of the drug in large doses, symptoms of hypercortisolism may appear. Symptoms: headache, increased blood pressure, heart failure, hyperglycemia, glucosuria. In case of overdose symptoms, you should consult a doctor. Under the supervision of a doctor, a gradual withdrawal of the drug, symptomatic treatment is carried out. In severe cases, emergency medical attention is needed. Side effect From the side of the immune system: very rarely – allergic skin reactions (itching, rash, urticaria). On the part of the skin and subcutaneous tissue: skin irritation (burning, redness), dry skin at the site of application of the ointment. With prolonged use: skin atrophy (sometimes irreversible), telangiectasia, striae, steroid acne, perioral dermatitis, purpura, changes in skin pigmentation, hypertrichosis, impaired wound healing, development of secondary skin infections. On the part of the endocrine system: with prolonged use, use on large areas of the skin, application under occlusive dressings or in the area of skin folds, hypercorticism (hyperglycemia, glucosuria, reversible inhibition of the function of the adrenal cortex, signs of Cushing’s syndrome) may develop, as a manifestation of the resorptive action of prednisolone. In this case, the drug should be discontinued. In children, due to the relatively larger surface of the skin, compared with body weight, the risk of decreased adrenal function is higher. Prolonged use of topical glucocorticosteroids may affect the growth and development of children. In the event of the above adverse reactions or adverse reactions not listed in this leaflet, you should consult a doctor. Storage conditionsStore at temperatures between 8°C and 15°C. Keep out of the reach of children. Buy Prednisolone ointment 5mg/g 10g №1 Price for Prednisolone ointment 5mg/g 10g №1