Gliatilin capsules 400mg №14×2

Name:
Gliatilin capsules 400mg N14.
Description:
Oval yellow opaque soft gelatin capsules containing a viscous colorless solution. The main active ingredient is choline alfoscerate. Release formCapsules 400mg N14 Pharmacological actionMeans used to treat diseases of the nervous system. Parasympathomimetic agents. Other parasympathomimetic agents. ATX code: N07AX02 Pharmacodynamics Choline alfoscerate is a transport form of choline and a precursor of phosphatidylcholine, which is potentially able to prevent membrane damage, as one of the pathogenesis factors of psychoorganic involutional syndrome, characterized by a decrease in cholinergic synaptic transmission and damage to the phospholipid composition of neuronal membranes. The chemical structure of choline alfoscerate (containing 40.5% choline) and the associated physicochemical properties of the molecule ensure that some of the choline crosses the blood-brain barrier. The results of preclinical and clinical studies confirm the ability of choline alfoscerate to influence mainly cognitive-mnestic functions, as well as emotional and behavioral activity, impaired in involutional pathology of the brain. Pharmacokinetics Pharmacokinetic characteristics of a radioactively labeled drug when administered were similar in different animal species (rats, dogs, monkeys) and gave the following results: rapid and complete absorption in the gastrointestinal tract, distribution of choline and its metabolites in various organs and tissues, including the brain , renal excretion was about 10% of the administered dose at 96 hours; the content of the drug in the brain tissues is higher compared to tritium-labeled choline. Indications for use Psychoorganic syndrome due to involutional and degenerative processes in the brain, the consequences of cerebrovascular insufficiency, such as primary and secondary cognitive impairment in the elderly, characterized by impaired memory, confusion, disorientation, decreased motivation, initiative, ability to concentrate. Behavioral and affective disorders in old age: emotional lability, increased irritability, decreased interest. Dosage and administration One capsule 2-3 times a day before meals. If necessary, the dosage can be increased on the recommendation of the attending physician. The duration of the course of treatment is determined by the doctor, taking into account the disease, the tolerance of the drug and the effect achieved. Use during pregnancy and lactation The use of Gliatilin during pregnancy and lactation (breastfeeding) is contraindicated. Precautions Care should be taken when driving vehicles or engaging in other activities that require increased concentration and / or speed of psychomotor reactions. Interaction with other drugs Drug interaction of the drug Gliatilin has not been established. Contraindications Hypersensitivity to choline alfoscerate or auxiliary components of the drug. Pregnancy, breastfeeding period; childhood. CompositionCapsule Each capsule contains: active substance – choline alfoscerate – 400 mg; excipients: glycerin, purified water; composition of the capsule shell: gelatin, ezitol (a mixture of mannitol and D-sorbitol), sorbitans (D-sorbitol and 1,4-sorbitan), sodium ethyl parahydroxybenzoate (E215), sodium propyl parahydroxybenzoate (E217), titanium dioxide (E171), iron oxide ( E172). Overdose Symptoms: nausea. When this symptom appears, it is recommended to reduce the dose of the drug. In case of overdose, symptomatic therapy is indicated. The efficacy of dialysis has not been established. Use in children The drug is not intended for use in children. There is no experience with the use of Gliatilin in children. Side effects Nausea (as a result of dopaminergic activation), in this case, reduce the dose of the drug. Allergic reactions are possible. Very rarely, abdominal pain and short-term confusion are possible. In case of adverse reactions, including those not listed in the Instructions for Use, you should consult a doctor. Storage conditions At a temperature not exceeding 25 ° C, out of the reach of children! Buy Gliatilin capsules 400mg No. 14×2 Price for Gliatilin capsules 400mg No. 14×2