Name Alfacholin solution for intravenous, intramuscular injection. 1000 mg / 4 ml in amp. is a transport form of choline and a precursor of phosphatidylcholine, which is potentially able to prevent membrane damage, as one of the factors in the pathogenesis of psychoorganic involutional syndrome, characterized by a decrease in cholinergic transmission and damage to the phospholipid composition of neuronal membranes. The chemical structure of choline alfoscerate (containing 40.5% choline) and the associated physicochemical properties of the molecule provide metabolic protection for choline in the brain. The results of preclinical and clinical studies confirm the ability of choline alfoscerate to interfere mainly with cognitive-mnestic functions, as well as emotional and behavioral activity, impaired in involutional pathology of the brain. PharmacokineticsAbsorption after oral administration – 88%. Easily penetrates the blood-brain barrier, accumulates mainly in the brain (the concentration reaches 45% of the concentration in the blood), lungs and liver. 85% is excreted by the lungs in the form of carbon dioxide, 15% – by the kidneys and through the intestines. Indications for use degenerative and involutional psychoorganic syndromes and the consequences of cerebrovascular insufficiency, such as primary and secondary cognitive impairments characterized by memory impairment, confusion, disorientation, decreased motivation, initiative and reduced ability to concentrate; changes in the emotional and behavioral sphere: emotional lability, increased irritability, decreased interest. Pseudo-depression of the elderly. Dosage and administration Usual dosage: one ampoule (1000 mg) per day intramuscularly or intravenously (slowly). When administered intravenously, the contents of the ampoule (4 ml) are diluted in 50 ml of saline, the infusion rate is 60-80 drops per minute. If necessary, the dosage can be increased on the advice of a doctor. The duration of therapy is determined by the doctor. Influence on the ability to drive vehicles and control mechanisms The drug does not affect the patient’s ability to drive a car and work with moving mechanisms. Precautions If nausea occurs after taking the drug, the dose should be reduced. The use of the drug during pregnancy and lactation is contraindicated. The use of the drug in children under 18 years of age is contraindicated due to the lack of data on efficacy and safety. Interaction with other drugs has not been established. Contraindications Hypersensitivity to the components of the drug. Pregnancy and lactation. Children’s age (up to 18 years). Composition One ampoule contains: Active substance: choline alfoscerate – 1000 mg. Excipient: water for injection – up to 4 ml. Overdose Symptoms: nausea, headache, agitation. Treatment: if these symptoms appear, the dose of the drug should be reduced. Side effect On the part of the digestive system: nausea (due to dopaminergic activation). In this case, the dose of the drug should be reduced. From the nervous system: headache, drowsiness, insomnia, anxiety, nervousness. Allergic reactions are possible. In case of adverse reactions, including those not listed in this leaflet, you should consult a doctor. Storage conditions In a place protected from light at a temperature not exceeding 25? Keep out of the reach of children. Buy Alfacholin solution for intravenous/ and intramuscular injection 1000mg/4ml in ampoules No. 5×1 /in/ and in/m/ injections of 1000mg/4ml in ampoules No. 5×1
Alfacholine solution for intravenous and intramuscular administration 1000mg/4ml in ampoules No. 5×1
$30.00
SKU: 79833
Category: Improvement of cerebral circulation
INN | CHOLINA ALPHOSCERATH |
---|---|
The code | 79 833 |
Barcode | 4 812 608 005 471 |
Dosage | 1000mg/4ml |
Active substance | Choline alfoscerate |
Manufacturer | Lekpharm SOOO, Belarus |
Reviews
There are no reviews yet.