Equator tablets 20mg/10mg №10×3

Equator Tablets: A Powerful Combination for High Blood Pressure Management

Equator tablets are a fixed-dose combination medication containing amlodipine and lisinopril, two effective drugs for treating high blood pressure (hypertension). This comprehensive guide provides you with detailed information about Equator tablets, including its composition, dosage, side effects, interactions, and precautions.

What are Equator tablets?

Equator tablets come in three strengths:

• 10mg/5mg: Containing 10mg of lisinopril and 5mg of amlodipine
• 20mg/5mg: Containing 20mg of lisinopril and 5mg of amlodipine
• 20mg/10mg: Containing 20mg of lisinopril and 10mg of amlodipine

How do Equator tablets work?

Lisinopril is an ACE inhibitor that helps relax blood vessels and lower blood pressure by blocking the production of a hormone that constricts blood vessels.

Amlodipine is a calcium channel blocker that also relaxes blood vessels and improves blood flow to the heart, helping to reduce chest pain (angina) and lower blood pressure.

The combined action of these two drugs provides a powerful and long-lasting effect in managing hypertension.

Key Benefits of Equator Tablets:

• Effective blood pressure control: Equator tablets effectively lower blood pressure, reducing the risk of heart attacks, strokes, and other cardiovascular complications.
• Convenience: Taking one tablet daily simplifies the medication regimen for patients.
• Cost-effective: Equator tablets can be a cost-effective option compared to taking separate medications.

Who are Equator tablets suitable for?

Equator tablets are indicated for the treatment of hypertension in adults who have been titrated to the appropriate doses of lisinopril and amlodipine.

Important Precautions and Contraindications:

• Pregnancy and breastfeeding: Equator tablets are not recommended during pregnancy and contraindicated during the second and third trimesters. It is also not recommended during breastfeeding.
• Renal insufficiency: Use with caution in patients with severe renal dysfunction. Monitoring of kidney function and potassium levels is crucial.
• Hepatic impairment: Equator tablets should be prescribed with caution in patients with liver disease, and the lowest recommended dose should be used.
• Other conditions: Use with caution in patients with conditions such as aortic stenosis, mitral stenosis, or history of angioedema.

Potential Side Effects:

• Common side effects: Headache, cough, dizziness, fatigue, ankle edema
• Less common side effects: Nausea, vomiting, constipation, muscle cramps, rash, sleep disturbances
• Rare side effects: More serious side effects, such as angioedema, pancreatitis, or liver problems, are possible but less frequent.

Drug Interactions:

• Potassium-sparing diuretics: May lead to hyperkalemia, especially in patients with renal insufficiency.
• Other antihypertensive drugs: May enhance the antihypertensive effect of Equator tablets.
• Diuretics: Can increase the risk of hypotension.
• Lithium: May increase the risk of lithium toxicity.
• CYP3A4 inhibitors: May increase the levels of amlodipine in the blood.
• CYP3A4 inducers: May reduce the levels of amlodipine in the blood.

Overdose:

• Symptoms: Excessive peripheral vasodilation, hypotension, tachycardia, bradycardia, cough, and other side effects.
• Treatment: Gastric lavage, activated charcoal, supportive care, and monitoring of vital signs.

Important Note: This information is not a substitute for professional medical advice. Always consult your doctor before taking Equator tablets or any other medication.

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