Vibrocil nasal drops (2.5mg/0.25mg)/1ml 15ml №1

Name:
Vibrocil drops
Description:
A clear, colorless to pale yellow solution with a slight lavender odor. The main active ingredient Dimetindene + phenylephrine Release form 15 ml in a dark glass bottle with a screw cap pipette. The bottle, along with instructions for use, is placed in a cardboard box. Dosage 15 ml Pharmacological action Decongestants and other nasal preparations for topical use. Code ATX R01AB01. Pharmacodynamics Vibrocil is a combined preparation containing phenylephrine and dimethindene. Phenylephrine is a sympathomimetic agent, when applied topically it has a moderate vasoconstrictive effect (due to stimulation of alpha-1-adrenergic receptors located in the venous vessels of the nasal mucosa), eliminates swelling of the nasal mucosa and its paranasal sinuses. Dimetindene is an antiallergic agent – an antagonist of histamine H1 receptors; does not reduce the activity of the ciliated epithelium of the nasal mucosa. Vibrocil is intended for topical use, and its activity does not depend on the concentration of active substances in the blood plasma. Indications for use Acute rhinitis (including runny nose with colds); allergic rhinitis (including hay fever); vasomotor rhinitis; chronic rhinitis; acute and chronic sinusitis; acute otitis media (as an auxiliary treatment). Preparation for surgical interventions in the nasal area and elimination of edema of the nasal mucosa and paranasal sinuses after surgical interventions in this area. Dosage and administration For children aged 1 to 6 years, 1-2 drops are used in each nasal passage 3-4 times a day. Children over 6 years old and adults use 3-4 drops in each nasal passage 3-4 times a day. Before use, it is recommended to thoroughly clean the nasal passages; bury in the nose, throwing back the head. This head position is maintained for several minutes. Use during pregnancy and lactation It is not recommended to use the drug during pregnancy and breastfeeding. Precautions Vibrocil should not be used for more than 7 days in a row. If symptoms persist for more than 7 days, you should consult a doctor. Prolonged use of the drug (more than 2 weeks) can cause tachyphylaxis and drug-induced rhinitis, and can also lead to the development of a systemic vasoconstrictor effect. You should not exceed the recommended doses, because. development of systemic action is possible. In children under the age of 6 years, only nose drops are used. Children aged 1 to 12 years should use the drug under adult supervision. Phenylephrine, like other vasoconstrictors, is contraindicated in patients currently receiving MAO inhibitors or who have received them within the previous 2 weeks. Vibrocil drops should be used with caution in patients suffering from arterial hypertension, cardiovascular diseases, hyperthyroidism, prostate adenoma, diabetes mellitus, epilepsy. As with any local vasoconstrictor, caution should be exercised when using Vibrocil drops in patients with severe reactions to sympathomimetics, which are manifested by the development of insomnia, dizziness, tremor, cardiac arrhythmias and increased blood pressure. Interaction with other drugs Phenylephrine, like other vasoconstrictors, is contraindicated in patients receiving MAO inhibitors or receiving them within 2 weeks prior to the start of Vibrocil drops. Do not prescribe the drug simultaneously with tri- and tetracyclic antidepressants, beta-blockers. Contraindications Hypersensitivity to the components of the drug. Atrophic rhinitis (including with a fetid discharge – ozena). Reception of MAO inhibitors (at the same time or in the previous 14 days). Angle-closure glaucoma. Composition 1 ml contains: phenylephrine 2.5 mg, dimethindene maleate 0.25 mg. Excipients: benzalkonium chloride, citric acid monohydrate, disodium phosphate anhydrous, sorbitol, lavender deterpene oil, purified water. Overdose In most cases, there were no symptoms of an overdose, however, symptoms such as fatigue, headache in the back of the head, dizziness, abdominal pain, nausea, vomiting, tremors or tremors, tachycardia, arterial hypertension, agitation, insomnia, pallor of the skin were sometimes reported. Treatment: the use of activated charcoal, laxatives (gastric lavage is not required); in adults and children over 6 years of age – intake of large amounts of fluid. There is no specific antidote. Hypertension caused by phenylephrine can be eliminated by the administration of an alpha-blocker. Side effectIn rare cases, there may be a feeling of dryness and burning of the nasal mucosa. Storage conditions The drug should be stored out of the reach of children. Store at a temperature not exceeding 30 °C. Buy Vibrocil nasal drops (2.5mg / 0.25mg) / 1ml 15ml No. 1 Price for Vibrocil nasal drops (2.5mg / 0.25mg) / 1ml 15ml No. 1 25mg)/1ml 15ml №1