Terbizil cream 1% 15g №1

Name:
Terbizil cream 1% in tubes 15g in a pack. No. 1 Main active ingredient Terbinafine hydrochloride Release form Cream Composition contains Terbizil cream The active substance is 10 mg of terbinafine hydrochloride in 1 g of cream. Excipients: sodium hydroxide, benzyl alcohol, sorbitan monostearate, cetyl palmitate, cetyl alcohol, cetostearyl alcohol, polysorbate 60, isopropyl myristate, purified water.
Description:
Cream of white or almost white color with a slight smell of almonds, easily washed off with water. Dosage 15 g Pharmacological properties Terbizil is an antifungal drug of the allylamine group with a wide spectrum of fungicidal action. Terbinafine inhibits the biosynthesis of sterols in the fungal membrane by inhibiting squalene epoxidase, which leads to intracellular accumulation of squalene and, as a result, to the death of the fungal cell. Terbinafine does not affect the cytochrome P450 enzyme system and the metabolism of hormones and other drugs dependent on the cytochrome P450 system. At low concentrations, terbinafine has fungicidal activity against dermatophytes, molds and some dimorphic fungi. The action on yeast fungi, for example of the genus Candida, may be fungicidal or fungistatic, depending on the strain of the fungus. Fungal infections can occur in the following areas of the body: Fungal infections of the feet (athlete’s foot) usually occur between the toes. They may extend to the sole, rib, and instep of the foot. The infection can affect one or both feet. The most common symptoms include inflammation, the formation of cracks and scales on the skin, and unpleasant itching. In more severe cases, small moist blisters form on the skin, deep painful cracks and skin peeling occurs; fungal infections of the nails (the fungus grows on or under the nail plate): the nail thickens and its color changes; fungal infections of the skin can occur in the folds of the body. These include inguinal folds, skin folds under the mammary glands and axillary pits, as well as the inner thighs, buttocks. A fungal infection is a moist patch of inflammation that is bright red in color with clear boundaries with peeling along the edges, spreading within the affected area. In some cases, skin peeling occurs in the depth of the fold and weeping erosions and painful cracks can form; superficial fungal infection of the skin can occur anywhere on the surface of the body. As the fungus grows, it spreads around the circumference with a patch of normal skin in the center. The fungus is shaped like a ring. Along the edges of the ring, the skin is raised and irritated, it is red and scaly; another form of superficial fungal infection (versus versicolor) is characterized by the appearance of brownish scaly (pityriasis) spots on the skin of the body, which turn white when exposed to sunlight. It is common in people who sweat excessively or work in hot, humid environments. When applied topically, <5% of the dose is absorbed, so the systemic effect is negligible. When Terbizil cream is used for 7 days, the concentration in the stratum corneum above the fungicidal level remains for 7 days after stopping the use of the drug. Indications for use Terbizil cream is a local antifungal drug. Terbizil cream is used for topical treatment of a fungal infection of the skin. For external use only. A fungal infection can affect the following areas of the body: The skin of the feet (athlete's foot). It is manifested mainly by lesions of the interdigital spaces of the skin, it can spread to the sole, edge and / or to the instep of the foot. The most common symptoms are inflammation, cracking or peeling of the skin, and unpleasant itching. In more severe cases, weeping blisters, flaking of the skin, or painful, deep cracks may appear. Fungal infection of the nails (fungi sprouts the nail or grows under the nail plate): the nail thickens and changes in color. If you notice such symptoms, be sure to contact your doctor, because Terbizil cream is used to treat such infections only in combination with Terbizil 250mg tablets. Fungi can infect the skin of body folds such as the groin, inner thighs, buttocks, underbust folds, and armpits. With these localizations of skin lesions by a fungal infection, the disease manifests itself in the form of redness, a clearly defined wet inflammation, with peeling along the edges and expansion of the affected area. Sometimes in the depth of the folds, the skin can exfoliate, weeping erosions and painful cracks can also form. A superficial fungal infection of the skin can develop on any area of the body. As the fungus grows, it spreads in a circular pattern, leaving normal-looking skin in the center. It looks like a ring. Along the edges of the irritation and looks red and scaly. Another form of superficial fungal infection is the appearance of scaly brown spots on the skin of the trunk, which turn white when exposed to sunlight. These spots can be very numerous in people who are prone to sweating or who work in hot and humid places. If you are not sure about the origin of existing skin lesions, you should consult your doctor before using Terbizil cream. Contraindications - if you are allergic (hypersensitive) to terbinafine or to one of the ingredients that make up Terbizil cream. - During pregnancy and lactation, it is necessary to consult your doctor before using Terbizil cream. Use during pregnancy and lactation Before using any medicine, consult your doctor or pharmacist. Do not use Terbizil cream while breastfeeding, as terbinafine hydrochloride, the active ingredient in Terbizil cream, passes into breast milk. Despite the fact that when applied topically, its amount is extremely small, during the application of Terbisil cream, contact of the child's skin with the treated mother's skin should not be allowed, even if it is breast skin. Method of application and doses Pierce the sealed tube with the help of a spike on the tip of the cap Always wash and dry the skin before using the cream. The cream should be applied once or twice a day to a previously washed and dried skin area. The cream should be applied to the affected skin and the surrounding area in a thin layer and rubbed in lightly. To speed up healing in case of infection between the fingers, the treated area can be covered with gauze, especially at night (push the affected areas of the skin apart). Duration of treatment depending on the type of infection: Fungal infection of the feet: 1 week / once or twice a day Fungal infection of the body folds: 1 week / once or twice a day Superficial skin lesions: 1 week / once or twice a day Pityriasis versicolor : 2 weeks / once or twice a day Treatment should be continued for one week, and in the case of pityriasis versicolor, up to 2 weeks, even if the affected area has healed earlier. In this case, it will be possible to avoid a recurrence of the infection, and the treatment will be successful. The cream quickly stops the development of the infectious process due to the impact on pathogenic fungi, causing their death. However, complete healing may take longer depending on the nature of the fungal infection. For example, in the case of pityriasis versicolor, it may take four weeks for the white spots to disappear. The effect of Terbizil cream persists after application, even if you have finished using the drug. If after two weeks of using the drug there is no improvement, consult your doctor. To avoid re-infection, the following hygiene rules should be followed: The affected area should be kept clean; always wash your hands after using the cream; use your personal towel; underwear should be changed frequently; cotton socks should be worn and shoes should be disinfected. Don't scratch the affected area despite itching, as this can cause further damage to the skin and slow down the healing process, or spread an infection. If you forget to apply Terbisil cream at the scheduled time If you forget to apply the cream at the scheduled time, apply it as soon as possible and then return to regular use. If you miss one application and remember it by the time of the next application, do not use a double dose. It is important to try to use the cream at the right time, as skipping the use slows down healing and increases the chance of recurrence. If you stop using Terbizil cream, treatment should be continued for one week, and in case of pityriasis versicolor - 2 weeks, even if the affected area has healed earlier. In this case, it will be possible to avoid a recurrence of the infection, and the treatment will be successful. If you have any other questions about the use of this medicine, ask your doctor or pharmacist. Side effects Like all medicines, Terbizil cream can cause side effects. The most common side effects (occur in at least 10 per 100 patients): irritation. Common side effects (occur in 1-10 patients per 100 patients): redness, itching, pain or sharp pain at the application site. If you experience these side effects, contact your doctor. These symptoms are usually mild and disappear after treatment is stopped. A hypersensitivity reaction can develop in response to any drug. Therefore, if you experience any of these symptoms, such as swelling of the treated area, soreness or redness, you should stop treatment and consult a doctor. If any side effect becomes severe, or if you notice any side effect not listed in this leaflet, please tell your doctor or pharmacist. Overdose The low systemic absorption of terbinafine in cream form makes it extremely unlikely to overdose. Terbizil cream is for external use only. Accidental ingestion of 2 tubes of cream of 15 g (300 mg of terbinafine) corresponds to the intake of the active ingredient of one tablet of Terbizil 250 mg. In case of accidental ingestion of the cream, symptoms of an overdose of terbinafine tablets may occur (for example, headache, nausea, epigastric pain and dizziness). If necessary, gastric lavage is carried out. Interactions with other drugs Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including those obtained without a doctor's prescription. The co-administration of any other topical preparations on the affected areas of the skin should be avoided. Precautions The cetyl alcohol and cetostearyl alcohol in the cream may cause local skin reactions (eg, skin inflammation, the result of skin contact with the cream, which is called contact dermatitis). Storage conditionsStore at temperatures from +15°С to +30°С. Keep out of the reach of children. Buy Terbizil cream 1% 15g №1 Price for Terbizil cream 1% 15g №1 Instructions for use for Terbizil cream 1% 15g №1