Rumalon solution for intramuscular injection in ampoules 1ml №5×5

Name:
Rumalon solution for i / m introduction. in amp. 1ml in cont. cell pack. No. 5×5 Main active ingredient Glycosaminoglycan-peptide complex
Description:
Transparent yellowish-brown solution with the smell of m-cresol without mechanical inclusions. Release form Solution for intramuscular injection in ampoules. Dosage 1 ml Pharmacological properties The drug Rumalon® contains a glycosaminoglycan-peptide complex from the cartilage tissue and bone marrow of young calves, obtained by extraction followed by deproteinization and delipidization. The action of Rumalon® is due to the combined action of its active components. Rumalon® normalizes the metabolism in cartilage hyaline tissue: enhances the biosynthesis of sulfated mucopolysaccharides and collagen, stimulates the regeneration of articular cartilage, reduces enzyme activity and inhibits catabolic processes in cartilage tissue. Indications for use Symptomatic treatment of osteoarthritis of the knee and/or hip joints. The decision to prescribe the drug should be made by the attending physician. Method of application and doses Rumalon® is administered deep intramuscularly: on the first day – 0.3 ml, on the second day – 0.5 ml, and then 3 times a week, 1 ml for 5-6 weeks. It is advisable to repeat the course of treatment 6 months after consulting a doctor. The drug is intended for intramuscular injection. Do not administer intravenously. Use in patients with hepatic and renal impairment: No data available. Use in children: Do not use in children. Use during pregnancy and lactation There are no data on the use of the drug Rumalon® in pregnant women, therefore Rumalon® should not be used during pregnancy. It is not known whether the components of the drug Rumalon® pass into breast milk, therefore, during lactation, treatment with Rumalon® should be discontinued. Influence on the ability to drive vehicles and work with special equipment Due to the possibility of developing such an adverse reaction as dizziness, care should be taken in activities that require an increased concentration of attention and speed of psychomotor reactions. Precautions If allergic reactions or hemorrhages occur, treatment should be discontinued. If necessary, the attending physician prescribes a second course of treatment. Do not use in children. The use of the drug during pregnancy and lactation is contraindicated. Before using the drug, you should consult a doctor to confirm the diagnosis. The therapeutic effect (reduction of pain, improvement of joint mobility) is usually observed 2-3 weeks after the start of treatment and persists for several months after the end of treatment. Interaction with other drugs When combined with non-steroidal anti-inflammatory drugs, it can reduce the dose of non-steroidal anti-inflammatory drugs. The drug enhances the effect of indirect anticoagulants, antiplatelet agents, fibrinolytics, which requires more frequent monitoring of blood coagulation parameters when used together. Contraindications Hypersensitivity to any of the components of the drug, rheumatoid arthritis, a tendency to bleeding, thrombophlebitis, pregnancy and lactation (for the duration of treatment, breastfeeding should be stopped). Children under 18 years of age (since efficacy and safety in children have not been established). With caution: in case of blood clotting disorders, diabetes mellitus, in people with increased body weight, in case of impaired liver and kidney function, in women planning pregnancy. Composition 1 ml contains: Active substance: extract from cartilage tissue and bone marrow of young calves, containing a glycosaminoglycan-peptide complex in an amount of at least 2.25 mg. Excipients: m-cresol, 1M hydrochloric acid solution, water for injection. OverdoseSymptoms: allergic reaction, hemorrhages at the injection site. Treatment: if necessary, symptomatic therapy is indicated. In case of accidental acute overdose, symptomatic treatment is used. All activities are carried out against the background of drug withdrawal. There have been no reported cases of drug overdose. Side effects From the side of the nervous system: headache, dizziness. On the part of the skin and subcutaneous fat: there are reports of cases of erythema, urticaria, eczema, maculopapular rash, accompanied or not accompanied by itching and / or swelling. From the gastrointestinal tract: dyspepsia, rare cases of nausea, vomiting have been reported. From the immune system: allergic reactions (rare), including anaphylactoid reactions, anaphylactic shock, very rare cases of angioedema have been reported. From the musculoskeletal system: in some cases, after 3-6 injections, there is an increase in joint pain, which disappears on its own and does not require discontinuation of the drug. Cases of bleeding at the injection site are noted. Storage conditions Store at a temperature not exceeding 25 ° C in a place protected from light. Keep out of the reach of children. Buy Rumalon solution for intramuscular injection in ampoules 1ml No. 5×5 Price for Rumalon solution for intramuscular injection in ampoules 1ml No. 5×5