Magnefar B6 Biopharm tablets 500mg/5mg №10×6

Name:
Magnefar B6 biopharm. Forms of release Tablets. INN Magnesium hydroaspartate tetrahydrate + pyridoxine hydrochloride. FTGMagnesium drug.
Description:
Oblong biconvex tablets, white, with a smooth surface, scored on one side. The risk is intended to facilitate the breaking of the tablet if it is difficult to swallow it whole. Composition Each tablet contains: active ingredients: magnesium hydroaspartate tetrahydrate 500 mg, which corresponds to 34 mg of magnesium ions, and pyridoxine hydrochloride (vitamin B6) 5 mg. Excipients: microcrystalline cellulose, magnesium stearate, hypromelose. Pharmacotherapeutic group Mineral additives. Other mineral additives. Magnesium based products. ATC code: A12CC Indications for use Treatment of confirmed magnesium deficiency in the body – both isolated and associated with other deficiency conditions. A combination of a number of the following symptoms may indicate a magnesium deficiency: – nervousness, irritability, mild anxiety, transient fatigue, slight sleep disturbances; – signs of anxiety, such as gastrointestinal cramps or palpitations (with a healthy heart); – Muscle cramps, tingling sensation. Magnesium may help relieve these symptoms. If after one month of treatment there is no improvement, continuation of monotherapy with this drug is impractical. Contraindications – if the patient has a hypersensitivity to magnesium hydroaspartate, pyridoxine hydrochloride (vitamin B6) or any other component of this medicine, if the patient has diarrhea, – if the patient has hypermagnesemia (increased concentration of magnesium in the blood), – if the patient has hypervitaminosis B6 (increased concentration of vitamin B6 in the blood), – if the patient has severe renal failure, – if the patient has severe arterial hypotension, – if the patient has atrioventricular blockade, – if the patient has a disease called myasthenia gravis ( acquired chronic disease characterized by rapid fatigue and weakening of skeletal muscles) – children under 6 years of age. Precautions when using – the drug should not be taken on an empty stomach, – do not exceed the recommended dose, as this can lead to diarrhea, which can cause unsafe dehydration in its consequences, – with prolonged use of the drug, it is necessary to control the concentration of magnesium in the plasma. In case of concomitant calcium deficiency, magnesium deficiency should be corrected before calcium supplementation is started. Take with caution digitalis glycosides (prescribed for heart failure). This dosage form is not prescribed for children under 6 years of age. Drug interactions and other forms of interaction Contraindicated combinations With levodopa: the activity of levodopa is inhibited by pyridoxine (unless taking this drug is combined with taking inhibitors of peripheral decarboxylase of aromatic L-amino acids). Any amount of pyridoxine should be avoided unless levodopa is taken in combination with inhibitors of peripheral aromatic L-amino acid decarboxylase. Combinations that are not recommended Simultaneous use of drugs containing phosphates or calcium salts may impair the absorption of magnesium in the intestine. Combinations to be taken into account When prescribing fluoroquinolones and tetracyclines orally, it is necessary to observe an interval of at least three hours between their intake and Magnefar B6 Biopharm, since magnesium preparations reduce the absorption of tetracyclines and fluoroquinolones. The use of cycloserine, hydralazine, isoniazid, penicillamine leads to a decrease in the content of vitamin B6 in the body. Diuretic drugs (furosemide, ethacrynic acid) increase the excretion of magnesium in the urine. Long-term potassium-sparing diuretic drugs may increase magnesium reabsorption in the renal tubules and lead to hypermagnesemia. Other medicinal products containing magnesium, such as laxatives and gastric acid detoxifiers, taken concomitantly with magnesium hydroaspartate may cause symptoms of magnesium toxicity, especially in persons with renal insufficiency. Pregnancy and lactation Clinical experience with the use of the drug in a sufficient number of pregnant women did not reveal any adverse effect on the occurrence of fetal malformations or fetotoxicity. The drug can be used during pregnancy only if necessary, on the advice of a doctor. Magnesium passes into breast milk. The use of the drug during breastfeeding should be avoided. Influence on the ability to drive vehicles and work with mechanisms Does not affect. Dosage and administration Magnefar B6 Biopharm tablets are taken orally after meals with a small amount of liquid. The dividing line on the tablet is designed to break the tablet to make it easier to swallow. Adults are advised to take 6-8 tablets per day. Children over 6 years old (weighing over 20 kg) – 4-6 tablets per day. The daily dose should be divided into 2-3 doses. Data on the maximum allowable daily dose are not available. Renal insufficiency: The drug is contraindicated in patients with severe renal insufficiency. Liver failure: Dose modification is not required. Duration of treatment The duration of treatment is usually one month. Treatment should be stopped immediately after the normalization of the level of magnesium in the blood. If you miss the next dose of the drug Magnefar B6 Biopharm Treatment should be continued, observing the indicated method of dosing the drug Magnefar B6 Biopharm. Do not take double doses to make up for a missed one. Overdose Overdose symptoms rarely occur in patients with normal renal function. Taking medication in doses that are significantly higher than recommended can cause: allergic reactions, nausea, vomiting, abdominal pain, diarrhea and dehydration, central nervous system depression, decreased reflexes, ECG disturbances. If diarrhea occurs, it is necessary to reduce the daily dose or temporarily stop taking the drug. Other overdose symptoms: asystole (no heartbeat), bradycardia (rare heartbeat), drowsiness, coma, hypotension (low blood pressure), muscle paralysis, kidney failure, respiratory failure. Treatment of overdose: it is necessary to exclude drugs containing magnesium, support breathing, rehydration, forced diuresis. In case of renal failure, hemodialysis or peritoneal dialysis. The specific antidote is calcium gluconate. If you take a dose greater than the recommended one, you should immediately consult a doctor. Side effects Like all medicines, Magnefar B6 Biopharm can cause side effects, although not everyone gets them. The following adverse reactions have been reported: Rare – may affect up to 1 in 1,000 people: Abdominal pain, nausea and diarrhea that usually resolves on its own, atrioventricular conduction disturbances may occur, reddening of the skin Very rare – may occur in less than 1 person in 10,000: Allergic reactions, including skin reactions Reporting adverse reactions If you experience any adverse reactions, please consult your doctor. This recommendation applies to any possible adverse reactions, including those not listed in the package insert. You can also report adverse reactions to the adverse drug reactions (actions) information database, including reports of drug failures. By reporting adverse reactions, you help to get more information about the safety of the drug. Storage conditionsStore at a temperature of 15°C to 25°C, protected from light and moisture. Keep out of the reach of children. Shelf life 3 years. Do not use the drug after its expiration date. Holiday conditions Without a prescription. Packing: 10 tablets in PVC/Al foil blister packs. 6 blisters with a leaflet are placed in cardboard packs. Buy Magnefar B6 Biopharm tablets 500mg/5mg No. 10×6