Name:
Complex caps.solid. in bl. in pack. No. 10х2
Description:
Capsules hard gelatin No. 2, with a cap and a body of orange color. Active ingredients: 1 capsule contains ascorbic acid (vitamin C) 100 mg, thiamine hydrochloride (vitamin B1) 15 mg, riboflavin (vitamin B2) 15 mg, pyridoxine hydrochloride (vitamin B6) 10 mg, cyanocobalamin (vitamin B12) 0.002 mg , folic acid 0.25 mg, nicotinamide 50 mg, calcium pantothenate 25 mg; excipients: lactose, monohydrate; silicon dioxide colloidal anhydrous; potato starch; calcium stearate; composition of the capsule shell: gelatin, dyes: sunset yellow FCF (E 110), titanium dioxide (E 171). Pharmacotherapeutic group Vitamins. Multivitamin complexes without additives. pharmacological properties. Complexcaps is a multivitamin preparation. The action of the drug is determined by the properties of its constituent water-soluble B vitamins and vitamin C, which are components of enzyme systems and actively affect various functions of the body: regulate energy and metabolic processes in the body, normalize the functioning of organs and systems, accelerate tissue regeneration processes, increase efficiency of the body during mental and physical stress, contribute to an increase in the body’s resistance to infectious diseases, adaptation to stress. Vitamin B1 (thiamine hydrochloride) is an important coenzyme in the metabolism of carbohydrates, takes part in the functioning of the nervous, cardiovascular and digestive systems. Vitamin B2 (riboflavin) is part of the flavin coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which take part in redox reactions, and is a catalyst for cellular respiration processes, takes part in maintaining normal visual acuity, and normalizes skin functions. Vitamin B6 (pyridoxine hydrochloride) plays an important role in the metabolism of amino acids, neurotransmitters and hemoglobin, is necessary for the regeneration of the skin and liver cells, the restoration of the nervous system, and the improvement of fat metabolism in atherosclerosis. Vitamin B12 (cyanocobalamin) is a growth factor, necessary for the normal course of hematopoiesis and maturation of erythrocytes, takes part in the synthesis of amino acids, nucleic acids and myelin, and has a beneficial effect on the functioning of the nervous system and liver. Nicotinamide is a component of the NAD (H) and NADP (H) cofactor, part of the glucose tolerance factor, takes part in the processes of tissue respiration, carbohydrate and lipid metabolism, is a specific anti-pellagic agent. Folic acid is necessary for the normal formation of blood cells; together with vitamin B12 stimulates erythropoiesis, takes part in the synthesis of amino acids, nucleic acids, in the metabolism of choline, in addition to anti-anemic effects during pregnancy, protects the fetus from the effects of teratogenic factors. Vitamin C (ascorbic acid) takes part in redox processes, is necessary for the growth and formation of bones, skin, teeth, capillary endothelium and for the normal functioning of the nervous and immune systems, plays an important role in blood clotting, tissue regeneration, normal capillary permeability, the formation of steroid hormones and components of connective tissue, increases the body’s resistance to infectious diseases. Pantothenic acid functions primarily as part of coenzyme A and takes part in the production of hormones and antibodies, plays an important role in oxidation processes, participates in carbohydrate and fat metabolism, and in the synthesis of acetylcholine, which is involved in the transmission of nerve impulses. Pharmacokinetics. The drug is well absorbed in the digestive tract, its metabolic products are excreted from the body mainly with urine. Indications Treatment of hypo- and avitaminosis caused by insufficient intake or increased need for vitamins. Contraindications Increased individual sensitivity to the components of the drug, acute thromboembolism, erythrocytosis or erythremia, children under 14 years of age. Malignant diseases (with the exception of megaloblastic anemia due to folic acid deficiency); folate-dependent tumors; hyperoxaluria. Precautions when usingBefore starting treatment, consult your doctor! It is possible to color urine yellow, which is a completely harmless factor and is explained by the presence of riboflavin in the preparation. Complexcaps should be used with extreme caution in patients with severe and acute forms of decompensated heart failure and angina pectoris. The product contains sunset yellow FCF (E 110), which can cause allergic reactions. The drug contains lactose, so it should not be used in patients with hereditary galactose intolerance, lactase deficiency, glucose-galactose malabsorption syndrome. Interaction with other drugs If you are taking any other drugs, be sure to inform your doctor about it, and if you are self-treated, consult a doctor or pharmacist about the possibility of using the drug! The drug can be used in complex therapy with drugs for the treatment of the underlying disease. Not recommended for use with other vitamin preparations. Ethyl alcohol reduces the absorption of thiamine. Vitamin C enhances the action of sulfonamides (the risk of crystalluria), penicillin, increases iron absorption, reduces the effectiveness of heparin and indirect anticoagulants. The absorption of vitamin C is reduced when used simultaneously with oral contraceptives. The simultaneous use of ascorbic acid with antacids containing aluminum may increase the excretion of aluminum in the urine. Therefore, the combined use of antacids and Complexcaps is not recommended, especially in patients with renal insufficiency. The combined use of ascorbic acid with barbiturates or primidone may increase the urinary excretion of ascorbic acid. Co-administration of cellulose with sodium phosphate may result in the metabolism of ascorbic acid to oxalate. The concomitant use of deferoxamine with ascorbic acid in the treatment of iron overload increases the tissue toxicity of iron, especially to the myocardium. Cases of cardiomyopathy and congestive heart failure have been reported in patients with idiopathic hemochromatosis and thalassemia receiving deferoxamine and then ascorbic acid. Ascorbic acid should be used with caution in these patients and under monitoring of cardiac function. The combined use of disulfiram with ascorbic acid, especially in the case of long-term use or in high doses, may disrupt the interaction of disulfiram-alcohol. Large doses of ascorbic acid can cause acidification of the urine, which can alter the rate of renal excretion of certain drugs, for example, accelerate renal excretion of mexiletine when administered concomitantly. The combined use of salicylates with ascorbic acid may increase the urinary excretion of ascorbic acid. Ascorbic acid can interfere with the biochemical determinations of creatinine, uric acid, and glucose in blood and urine samples. Folic acid can reduce plasma concentrations of anticonvulsants, in particular phenytoin, phenobarbital and primidone, resulting in a mutual decrease in clinical efficacy. Therefore, patients receiving antiepileptic therapy may require dose adjustments and close medical supervision when taking folic acid. The antibacterial agents chloramphenicol and co-trimoxazole may interfere with folic acid metabolism. Sulfasalazine may reduce the absorption of folic acid. Preparations containing folic acid or its derivatives may reduce the effectiveness of methotrexate. Antibodies that cross-react with other folic acid analogues, including methotrexate, folinic acid (leucovorin), and aminopterin, have been found in patients with hypersensitivity to folic acid. Riboflavin is incompatible with streptomycin and reduces the effectiveness of antibacterial drugs (oxytetracycline, doxycycline, erythromycin, tetracycline and lincomycin). The tricyclic antidepressants, imiprdmits, and amitriptyline inhibit riboflavin metabolism, especially in cardiac tissues. Alcohol impairs intestinal absorption of riboflavin. The simultaneous use of antidepressants, tricyclic or phenothiazines, with riboflavin may increase the requirements of the latter. Probenecid reduces the gastrointestinal absorption of riboflavin. At high doses, riboflavin may interfere with the results of diagnostic tests for the determination of catecholamines and urobilinogen in the urine. Vitamin B6 affects the metabolism of certain drugs. High doses of vitamin B6 reduce the antiparkinsonian effect of levodopa. Pyridoxine enhances the peripheral conversion of levodopa and thus reduces its effectiveness in the treatment of Parkinson’s disease. Vitamin B6 is an antagonist of isoniazid and thiosemicarbazones, correcting sideroblastic anemia caused by these anti-tuberculosis drugs. Prolonged use of penicillamine can lead to the development of vitamin B6 deficiency. Hydralazine and cycloserine are also pyridoxine antagonists, and the simultaneous use of the vitamin with them reduces the adverse neurological reactions caused by these drugs. The amount of vitamin B6 is reduced when taken simultaneously with oral contraceptives. Vitamin B6 affects the processes of polarization in the area of neuromuscular synapses, therefore, it can weaken the curare-like effect. Concomitant use of chloramphenicol, cycloserine, ethionamide, hydralazine, isoniazid, penicillamine or immunosuppressants with pyridoxine may lead to anemia or peripheral neuritis because they are pyridoxine antagonists or increase pyridoxine excretion by the kidneys. In patients receiving these drugs, pyridoxine requirements may be increased. The simultaneous use of estrogens, hydralazine, isoniazid and penicillamine may increase the need for pyridoxine. The combined use of levodopa with pyridoxine is not recommended, since the antiparkinsonian effects are leveled even by 5 mg of pyridoxine; this problem does not occur when combined with carbidopa-levodopa or with peripheral decarboxylase inhibitors. Large doses of pyridoxine may lead to a decrease in serum concentrations of phenytoin and phenobarbital in some patients. Colchicine, cimetidine, calcium preparations, ethyl alcohol, neomycin, para-aminosalicylic acid, biguanides, cholestyramine, potassium chloride and methyldopa reduce the absorption of vitamin B12. Chloramphenicol and vitamin C affect the absorption of vitamin B12. Serum concentrations of cyanocobalamin may be reduced by oral contraceptives. Precautions Not recommended for use with other vitamin preparations to avoid overdose and side effects. Care must be taken when taking the drug in patients with a history of liver dysfunction or disease, diabetes mellitus, gout, arrhythmias, migraines, alcohol abuse, gastric ulcer in the acute stage. The drug is not intended for prophylactic use. Increased use of ascorbic acid over a long period can lead to an increase in renal clearance of ascorbic acid and its deficiency with rapid cancellation. Large doses are associated with the formation of calcium oxalate kidney stones. Vitamin C can interfere with test results for urine glucose, uric acid, and serum creatinine. High doses of vitamin C can lead to false negative results from occult blood tests. Use during pregnancy or lactation Doses of some vitamins in the medicinal product exceed the average daily requirement for them for pregnant or lactating mothers. Vitamins B1, B6 and B12 pass into breast milk. High doses of vitamin B6 may inhibit milk production. The use of this drug during pregnancy or lactation is possible only on the prescription of a doctor after a thorough assessment of the risk/benefit ratio. The ability to influence the reaction rate when driving motor transport or other mechanisms suggests that the drug may have a negative effect when driving a car or working with complex equipment. Children The drug in this dosage form is not used for children under the age of 14 years. Dosage and administrationComplexaps should be taken orally during meals with plenty of water. Adults and adolescents over 14 years old: 1-2 capsules 1 time per day, the course of treatment is 20 days. If necessary, repeat the course after 2 months. In severe diseases of the liver and kidneys, the possibility of using the drug should be agreed with the doctor. OverdoseSymptoms: In case of an overdose of the drug, dyspepsia (nausea, vomiting, diarrhea, epigastric pain), allergic reactions (itching, skin rash), skin and hair changes, liver dysfunction, headache, drowsiness, lethargy, flushing of the face can be observed. , irritability. Symptoms of chronic overdose: formation of oxalate kidney stones, renal failure, peripheral neuropathy, hyperglycemia, symptoms characteristic of excess uric acid (gout), duodenal ulcers, arrhythmias, skin hyperpigmentation, hypothyroidism, damage to the optic nerve, exacerbation of existing mental disorders, inhibition of effects pyridoxine. In such cases, the drug is stopped. Treatment: treatment includes gastric lavage, the introduction of activated charcoal, the use of symptomatic agents. Isoniazid is an antidote for vitamin B6. Side effects The recommended doses are usually well tolerated. Some individuals may experience adverse reactions: From the immune system: possible hypersensitivity reactions to the components of the drug, including anaphylactic shock, bronchospasm. From the side of metabolism and digestion: hypercalcemia. From the nervous system: headache, dizziness, drowsiness. On the part of the organs of vision: blurred vision. From the digestive tract: dyspepsia, nausea, vomiting, belching, stomach pain, constipation, diarrhea, increased secretion of gastric juice. From the skin and subcutaneous tissue: rash, urticaria, itching, redness. From the side of the kidneys and urinary tract: discoloration of urine, hypercalciuria. General disorders: hyperthermia, irritability, hyperhidrosis, back pain. During long-term use of high doses, the following adverse reactions may occur. From the side of metabolism and digestion: hyperuricemia, impaired glucose tolerance, hyperglycemia. From the nervous system: paresthesia, peripheral neuropathy. From the side of the heart: arrhythmias. From the digestive tract: gastrointestinal disorders, stomach cramps. sides of the skin and subcutaneous tissue: hair loss, seborrhea. From the side of the kidneys and urinary tract: renal failure, increased urination, hyperoxaluria. From the blood and lymphatic system: hemolytic anemia (in some patients with glucose-6-phosphate dehydrogenase deficiency). Laboratory indicators: a temporary increase in aspartate aminotransferase, alkaline phosphatase, lactate dehydrogenase. In case of any adverse events or negative reactions, consult your doctor regarding the further use of the drug. Storage conditions Store in the original packaging at a temperature not exceeding 25 °C. Keep out of the reach of children! Buy Complexcaps capsules No. 10×2 Price for Complexcaps capsules No. 10×2
INN | POLYVITAMIN+MULTIMINERAL |
---|---|
The code | 84 791 |
Barcode | 4 820 011 184 560 |
Active substance | Vitamin and mineral complex |
Manufacturer | Kyiv Vitamin Plant PJSC, Ukraine |
Importer | UE "MedPharmInvest", Minsk, Republic of Belarus, Minsk region, Minsk district, Papernyansky village, 50/1-1 district, Dubovlyany village |
Be the first to review “Complexcaps capsules №10х2” Cancel reply
Related products
Vitamin - mineral complexes
$28.00
Vitamin - mineral complexes
Swiss Energy Magnesium + B complex effervescent tablets No. 20
$32.00
Vitamin - mineral complexes
Doppelherz Active from A to Zinc with peach and passion fruit flavor effervescent tablets №15
$24.00
Reviews
There are no reviews yet.