Laferon-PHARMBIOTEK nasal lyophilizate for the preparation of nasal drops 1,000,000 IU No. 1

Name:
Laferon-PharmBiotek naz.lyof.d/app.drop.naz.1 million IU in vial in pack No. 1
Description:
Lyophilized powder or porous mass of white color, hygroscopic. The main active ingredient Interferon alfa-2b Release form Lyophilisate Dosage 1 million IU Special instructions To preserve the immunobiological activity of the drug, only water cooled to room temperature (15 °C to 25 °C) should be used to dissolve the powder. Indications for useLaferon-PharmBiotec® Nasal is used for the treatment and prevention of acute respiratory viral and viral-bacterial infections in adults and children, including newborns. For the purpose of prevention, they are used when there is a threat of infection (during the epidemic period, upon contact with a patient with an acute respiratory viral infection). For therapeutic purposes, it should be used as early as possible – at the first signs of the disease. The effectiveness of the drug is higher, the earlier its use is started. Dosage and administration Open a bottle with a dry powder of the drug and fill it with 5 ml of boiled water cooled to room temperature (from 15 ° C to 25 ° C). A syringe with a volume of at least 5 ml can be used as a dosing device. Carefully close the vial with a rubber stopper and, gently oscillating, completely dissolve the powder. Replace the rubber stopper with the supplied dropper cap. Drops are ready for use. After each use of the drug, close the dropper with a protective cap. After filling the vial, 1 ml of the prepared solution contains about 200 thousand IU of interferon. When using the supplied dropper cap, 1 ml of the prepared solution contains 32 drops. One drop contains 6250 IU of interferon. For the treatment of influenza and other respiratory viral infections, drops are instilled into each nasal passage in the following doses: for infants, including premature babies – 1 drop 4-5 times a day (single dose 12500 IU, daily dose 50000 – 62500 IU); children from 1 to 7 years old – 2-3 drops 4-5 times a day (single dose 25000-37500 IU, daily dose 100000-187500 IU); children over 7 years old – 2-3 drops 5-6 times a day (single dose 25000-37500 ME, daily dose 125000-225000 ME); adults – 4-5 drops 6-8 times a day (single dose 50,000-62,500 IU, daily dose 300,000-500,000 IU). Usually, the course of antiviral treatment with Laferon-PharmBiotec® Nasal is 3-5 days. For the purpose of prevention, upon contact with the patient and in case of hypothermia, Laferon-PharmBiotec® Nasal is used in accordance with age dosages 2 times a day for 5-7 days: – single dose for infants, including premature babies – 12500 IU, daily dose – 25000 IU; – a single dose for children from 1 to 7 years old – 25000-37500 IU, daily dose – 50000-75000 IU; – a single dose for children over 7 years old – 25000-37500 IU, daily dose – 50000-75000 IU; – single dose for adults – 50000-62500 IU, daily dose – 100000-125000 IU; If necessary, preventive courses are repeated. With a single contact, a single application is sufficient. With a seasonal increase in the incidence – once in the morning with an interval of 1-2 days. Use during pregnancy and lactation In pregnant women and nursing mothers, the use of the drug has not been studied. Interferon alfa-2b is able to reduce the activity of P-450 cytochromes and thereby affect the metabolism of cimetidine, phenytoin, chimes, theophylline, diazepam, propranolol, warfarin, and some cytostatics. As a result, the neurotoxic, myelotoxic or cardiotoxic effects of these drugs may be enhanced. Caution should be used simultaneously with narcotic, hypnotic and sedative drugs. Interferons can influence oxidative metabolic processes. This should be taken into account when used simultaneously with drugs that are metabolized by oxidation (including xanthine derivatives – aminophylline and theophylline). With simultaneous use with theophylline, it is necessary to control the concentration of the latter in the blood serum and, if necessary, adjust the dosing regimen. There are no data on negative interactions with complex therapy. Contraindications Established allergy to interferon and excipients of the drug. Active ingredient: human recombinant interferon alpha-2b. The vial contains 1 million International Units (IU) of interferon. Excipients: sodium chloride, dextran 70, potassium dihydrogen phosphate, anhydrous sodium hydrogen phosphate. Overdose Cases of acute overdose of the drug were not observed. Side effects Short courses of treatment with interferon in the form of nasal drops do not cause any side effects. Storage conditionsKeep in a place protected from light, at a temperature of 2 °C to 8 °C. Keep out of the reach of children. After opening the vial and preparing the solution, store the drug for 5 days in the refrigerator or 2 days at room temperature (from 15 ° C to 25 ° C). The prepared solution should be protected from direct sunlight. Buy Laferon-PHARMBIOTEK nasal lyophilisate for the preparation of nasal drops 1,000,000 IU No. 1 Price for Laferon-PHARMBIOTEK nasal lyophilisate for the preparation of nasal drops 1,000,000 IU No. 1