Name:
Castor oil internal approx. in fl 30g in pack №1 Borisovsky ZMP
Description:
Transparent, thick, viscous, colorless or slightly yellowish liquid with a specific odor. The main active ingredient Castor oil Release form oil Dosage 30 g Pharmacological properties Pharmacodynamics Laxative. When ingested, it is cleaved by lipase in the small intestine to form ricinoleic acid, which causes irritation of the intestinal receptors throughout its entire length and a reflex increase in peristalsis. The laxative effect usually occurs after 5-6 hours. When taking castor oil, there is also a reflex contraction of the muscles of the uterus. Pharmacokinetics After oral administration in the alkaline environment of the duodenum in the presence of bile, under the influence of lipase, ricinoleic acid is formed from the oil. The absorption of ricinoleic acid is inversely proportional to the dose taken. With the introduction of oil at a dose of 4 g, the absorption of ricinoleic acid is about 100%, when administered at a dose of 50 g, only 36% is absorbed (the rest of the acid is excreted with feces within 24 hours), when administered at a dose of 60 g, the proportion of absorbed acid is only ten %. The absorption rate of ricinoleic acid is half that of oleic acid. For the development of a laxative effect, it is necessary to take at least 10 g of oil. The absorbed part of ricinoleic acid undergoes β-oxidation in the liver and skeletal muscles and is included in metabolic processes. Indications for use short-term symptomatic treatment of constipation; bowel preparation before diagnostic procedures. Dosage and administration Inside. Adults: 15-30 g (1-2 tablespoons) once a day. For children from 12 to 18 years old, the drug is prescribed by a doctor at 10-15 g (1 dessert – 1 tablespoon) once a day. Duration of application – no more than 3 days. Use during pregnancy and lactation The use of the drug during pregnancy is contraindicated. If necessary, the use of the drug during lactation should stop breastfeeding for the entire period of treatment. Influence on the ability to drive vehicles and control mechanisms While taking castor oil, it is not recommended to drive a vehicle, you should refrain from other operator activities due to a possible violation of concentration during the onset of the effect. Precautions The drug can only be used if the desired effect is not obtained by changing the diet or the use of laxatives that increase the volume of intestinal contents. Patients with unstable fluid balance (eg, patients with impaired renal function, elderly patients) are at increased risk of dehydration, the symptoms of which are oliguria and thirst. Before prescribing laxatives, it is necessary to restore the water balance, ensure the intake of a sufficient amount of fluid. In case of bleeding from the rectum or lack of bowel movements after taking a laxative, you should consult a doctor. It is not recommended to use castor oil as a laxative for more than 3 days, since digestion may be disturbed, as well as the absorption of vitamins A and D, with the development of corresponding hypovitaminosis. It is unacceptable to use castor oil in the treatment of drugs obtained from the male fern, because. at the same time, their systemic absorption and the development of a neurotoxic effect are possible. The use of the drug in children under 12 years of age is contraindicated. Consult a physician before use in children over 12 years of age. Interaction with other drugs When used simultaneously, it reduces the absorption of fat-soluble vitamins A, D and K. In doses up to 4 g / day, it increases the absorption of fat-soluble drugs – male fern extract, mebendazole, griseofulvin, probucol. With simultaneous use with saline laxatives, a sharp increase in the laxative effect is possible. M-anticholinergic agents (atropine sulfate, platifilin, pirenzepine), antispasmodics (papaverine, drotaverine) weaken the effect of castor oil. Enhances the effect of agents that stimulate the contractile activity of the myometrium (methylergometrine, ergometrine, oxytocin, prostaglandins) up to the threat of uterine rupture during childbirth. Chronic, spastic constipation, constipation of neurogenic and endocrine origin; acute inflammatory bowel disease (including appendicitis), intestinal stenosis and atony; peptic ulcer of the stomach and duodenum; inflammatory bowel disease (ulcerative colitis, Crohn’s disease, irritable bowel syndrome, enteritis, colitis); severe dehydration with loss of electrolytes; acute febrile states; cachexia; mechanical intestinal obstruction; abdominal pain of unknown origin; intestinal and uterine bleeding; acute and chronic glomerulonephritis; tubulointerstitial nephritis; poisoning with fat-soluble poisons (including gasoline, tetrachloride carbon, male fern extract); pregnancy; lactation; children’s age (up to 12 years). Composition Castor oil – 30 g. Overdose Develops when taking castor oil at a dose of more than 7 g / kg of body weight. Characterized by the appearance of diarrhea, sharp pains of a spastic nature in the abdomen, impaired renal function, dizziness, hallucinations, loss of consciousness. Specific antidotes are atropine sulfate and loperamide. Helpful measures include drug withdrawal, replenishment of fluid and electrolyte losses (preferably combined oral and intravenous administration), supportive and symptomatic therapy aimed at eliminating the disorders that have arisen. With the development of neurotoxic effects, diazepam 5–10 mg is administered intravenously. Side effectsAfter taking the drug, allergic reactions, flatulence, abdominal pain, nausea, diarrhea, and water and electrolyte imbalance are possible. With prolonged use – digestive disorders, enterocolitis, hypovitaminosis A and D, the development of addiction, intestinal atony. Storage conditions In a place protected from light, at a temperature not exceeding 25? Keep out of the reach of children. Buy Castor oil for oral administration 30g №1 Price for Castor oil for oral administration 30g №1Instruction for use for Castor oil for oral administration 30g №1
INN | CASTOR OIL |
---|---|
The code | 69 259 |
Barcode | 4 810 201 002 156 |
Dosage | 30g |
Active substance | Castor oil |
Manufacturer | Borisovsky ZMP, Belarus |
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