Omeprazole capsules 20mg №10×3

Name Omeprazole caps. The main active ingredient omeprazole in the form of omeprazole pellets Release form Capsules Dosage 20 mg Indications for use – peptic ulcer of the stomach and duodenum (treatment and prevention of relapses); – Helicobacter pylori eradication therapy in infected patients with gastric ulcer and duodenal ulcer (only as part of combination therapy); – peptic ulcer of the stomach and duodenum associated with the use of non-steroidal anti-inflammatory drugs (NSAIDs), stress ulcers (treatment and prevention in patients at risk of their occurrence); – reflux esophagitis; – gastroesophageal reflux (including symptomatic); – Zollinger-Ellison syndrome. Children: Children over 1 year old and weighing at least 10 kg: – treatment of reflux esophagitis; – symptomatic treatment of heartburn and acid regurgitation in gastroesophageal reflux disease. Children over 4 years of age: – duodenal ulcer caused by Helicobacter pylori (as part of complex therapy). Dosage and administration It is recommended to take the capsules in the morning, preferably before meals, swallowing whole and half a glass of water, without chewing or crushing the capsule. For patients with swallowing disorders or children, you can open the capsule and take the contents, after mixing it with a small amount of still water or a slightly acidic liquid (fruit juice, applesauce), drink a little water. The contents of the capsule are mixed with liquid immediately before use or no more than 30 minutes before taking the drug. Dosage in adults Treatment of duodenal ulcer in the acute phase The recommended dose is 20 mg / day. The course of treatment averages 2 weeks. In cases where complete scarring does not occur after the first course of taking omeprazole, a second two-week course of therapy is usually prescribed. In case of duodenal ulcer resistant to therapy, 40 mg / day is prescribed; scarring occurs within 4 weeks. Prevention of exacerbations of peptic ulcer of the stomach and duodenum The recommended dose is 20 mg / day. If necessary, the dose can be increased to 40 mg / day. Treatment of gastric ulcer in the acute phase The recommended dose is 20 mg / day. The course of treatment averages 4 weeks. In cases where, after the first course of taking the drug, the ulcer has not completely healed, a repeated 4-week course of treatment is usually prescribed, during which a cure is achieved. With gastric ulcer resistant to therapy, the drug is prescribed at 40 mg / day; recovery usually occurs within 8 weeks. Elimination of Helicobacter pylori in gastric ulcers Various treatment regimens can be used with the choice of antibiotics for a particular patient. Selection should be made in accordance with national, regional and local resistance data and treatment guidelines. Triple therapy: Omeprazole 20 mg + clarithromycin 500 mg + amoxicillin 1000 mg each twice a day for one week, or Omeprazole 20 mg + clarithromycin 250 mg or 500 mg + metronidazole 400 mg (or 500 mg or tinidazole 500 mg), each taken 2 times a day for one week, or omeprazole 40 mg + amoxicillin 500 mg + metronidazole 400 mg (or 500 mg or tinidazole 500 mg), each taken 3 times a day for one week. After the elimination of Helicobacter pylori, further treatment of gastric ulcer in the acute phase should be carried out according to the standard treatment regimen. In cases where the test for Helicobacter pylori remains positive after therapy, the course of treatment can be repeated. Treatment of NSAID-related gastric and duodenal ulcers The recommended dose is 20 mg/day. Most patients heal within four weeks. In cases where, after the first course of treatment, the ulcer has not completely healed, a repeated 4-week course is usually prescribed. To prevent NSAID-related gastric and duodenal ulcers in patients at risk (age over 60 years, history of gastric and duodenal ulcers, history of gastrointestinal bleeding), the recommended dose is 20 mg / day. Treatment of reflux esophagitis The recommended dose is 20 mg/day. Most patients heal within 4 weeks. In cases where, after the first course of treatment, the ulcer has not completely healed, a repeated 4-week course is usually prescribed. In patients with severe reflux esophagitis, a dose of 40 mg / day is recommended, the course of treatment is an average of 8 weeks. For long-term treatment of patients with healed reflux esophagitis (in remission), 10 mg / day is prescribed as long-term maintenance therapy. If necessary, the dose can be increased to 20-40 mg. For symptomatic treatment of gastroesophageal reflux disease, the dosing regimen is set individually. Assign 10-20 mg / day. The course of treatment is 4 weeks. If after the end of therapy the symptoms do not disappear, it is recommended to change the treatment regimen. Treatment of Zollinger-Ellison syndrome In Zollinger-Ellison syndrome, the dosage regimen is selected individually and treatment is continued according to clinical indications for as long as necessary. The recommended starting dose is 60 mg/day. All patients with severe disease, as well as in cases where other therapeutic methods have not led to the desired result, should be effectively monitored and more than 90% of patients are maintained on a dose of 20-120 mg / day. In cases where the daily dose of omeprazole exceeds 80 mg, the dose should be divided into two doses per day. Dosage in children Clinical experience with omeprazole in children is limited. Treatment should be under the supervision of a specialist. In the case of severe reflux esophagitis resistant to other types of therapy, children over 2 years of age weighing more than 20 kg are prescribed 20 mg / day (equivalent to about 1 mg / kg / day). The duration of treatment is 4-8 weeks. Children aged 1 to 2 years are prescribed at a dose of 10 mg / day. At the same time, the contents of the capsule are poured into 50 ml of drinking water, after mixing, half of this volume of liquid is measured and given to the child to drink. The dose may be increased to 40 mg once daily if necessary. For the treatment of Helicobacter pylori duodenal ulcer in children and adolescents, the choice of treatment regimen should be made in accordance with national, regional and local guidelines regarding bacterial resistance, duration of treatment (usually 7 days, but sometimes up to 14 days), and appropriate the use of antibacterial agents. Children weighing 15-30 kg: omeprazole 10 mg + amoxicillin 25 mg/kg + clarithromycin 7.5 mg/kg body weight, each drug 2 times a day for one week. Children weighing 31-40 kg: omeprazole 20 mg + amoxicillin 750 mg + clarithromycin 7.5 mg / kg body weight, each drug 2 times / day for one week. Children weighing more than 40 kg: omeprazole 20 mg + amoxicillin 1000 mg + clarithromycin 500 mg, each drug 2 times / day for one week. Special Populations In patients with impaired renal function and elderly patients (over 65 years), no dosage adjustment is required. In patients with impaired liver function, the dose should not exceed 10-20 mg / day. Contraindications Hypersensitivity to omeprazole or any excipients, children under 1 year of age (body weight less than 10 kg). Omeprazole, like other proton pump inhibitors (PPIs), should not be co-administered with nelfinavir. Composition 1 capsule contains: active ingredient – omeprazole in the form of omeprazole pellets 8.5% – 20 mg; excipients: mannitol, sucrose, calcium carbonate, lactose, disodium hydrogen orthophosphate, sodium lauryl sulfate, hydroxypropyl methylcellulose, methacrylic acid L30D, propylene glycol, cetyl alcohol, sodium hydroxide, polysorbate 80, povidone S-630, titanium dioxide (E 171). Capsule composition: titanium dioxide (E 171), methyl parahydroxybenzoate, propyl parahydroxybenzoate, gelatin. Buy Omeprazole capsules 20mg No. 10×3 Price for Omeprazole capsules 20mg No. 10×3