Name Bioflor solution. Release formSuspension. MNN coli. FTGMibp-eubiotic. General characteristicsSuspension of grayish-white color with a specific smell and taste. During storage, the formation of a loose amorphous precipitate is allowed, which breaks when shaken. CompositionIngredients per 100 ml: Active substance: E. coli M-17* – not less than 100×108 live cells at the time of manufacture and not less than 100×107 live cells at the end of the expiration date Excipients: Sodium chloride – 0.7 g (GF RB II volume 2, p. 740) Purified water – up to 100 ml (GF RB II volume 2, p. 309) A mixture of vegetable extracts (soybeans, – 0.8 g of dill, beets, mint, garlic, parsley, cabbage) and propolis (STP-OS-029) *100 ml of an aqueous solution of sodium chloride and a mixture of extracts of vegetables and propolis maintain the viability of E. coli M-17 in the amount of at least 100 × 107 living cells at the end of the expiration date Composition per 250 ml: Active substance : E. coli M-17 *- not less than 250×108 live cells at the time of manufacture and not less than 250×107 live cells at the end of the expiration date 740) Purified water – up to 250 ml (SF RB II volume 2, p. 309) A mixture of extracts of vegetables (soybeans, – 2.1 g of dill, beets, mint, garlic, parsley, cabbage) and propolis (STP-OS-029 ) *250 ml of an aqueous solution of sodium chloride and a mixture of extracts of vegetables and propolis ensure the maintenance of the viability of E. coli M-17 in the amount of at least 250×107 living cells at the end of the shelf life. Pharmacotherapeutic group Antidiarrheal microorganisms. Pharmacological properties Pharmacological properties of Bioflora are determined by living Escherichia coli contained in it – strain E. coli M-17. Escherichia coli E. coli M-17 have antagonistic activity against a wide range of pathogenic and opportunistic microorganisms, including shigella, salmonella, proteus, staphylococcus, klebsiella, which in turn contributes to the normalization of intestinal microflora. Indications for use Bioflor is used in complex therapy for: chronic diseases of the gastrointestinal tract (nonspecific and specific chronic colitis and enterocolitis accompanied by diarrheal syndrome); gastrointestinal disorders caused by an imbalance in the intestinal microflora; in convalescents after acute intestinal infections. Use in children Liquid dosage form Bioflor is intended for use in children from 6 months of age. Method of application and dosage The drug can be used in a mixture with water or liquid food (50-100 ml). The greatest effect is achieved when Bioflora is used separately 30 minutes before a meal or 1.5 hours after a meal. To achieve a therapeutic effect, the drug should be taken for at least 3-5 days. 1 dose is 10 ml of the drug and contains about 109 live bacteria of Escherichia coli E. coli M-17. For dosing, graduated syringes or spoons should be used. The volume of one dessert spoon is 10 ml; The volume of one teaspoon is 5 ml. Children: from 6 months to 1 year – 1 dose per day (10 ml) in 2-3 doses; from 1 year to 3 years – 2 doses per day (20 ml) in 2-3 doses; from 3 years to 6 years – 4 doses per day (40 ml) in 2-3 doses. Due to the presence of herbal extracts in the medicinal product, intake in children should be started with small amounts, gradually increasing the dose. When used against the background of antibiotic therapy, a 2-3 hour interval between the use of antibacterial agents and Bioflor solution is recommended. The use of the drug in children over 6 years of age and in adults is possible after a medical consultation to clarify the single, daily doses and duration of treatment, depending on the severity of symptoms of dyspepsia. If the symptoms persist for a long time and / or the patient’s condition worsens, and / or the appearance of new symptoms, it is necessary to stop taking the Bioflor solution and consult a doctor. Side effects In rare cases, there may be a slight increase in the severity of dyspeptic disorders, which usually stop on their own and do not require discontinuation of treatment. In case of a severe reaction, the use of the drug should be discontinued. There is a risk of developing an allergic reaction to the components of the drug. If you experience undesirable effects that are not described in the instructions, you should consult your doctor. Contraindications Hypersensitivity to the components of the drug; specific and nonspecific ulcerative colitis; children up to 6 months. Overdose There are currently no reports of adverse effects in case of overdose. Precautions The presence of a severe allergy in the patient. If the allergy is caused by an imbalance in the gastrointestinal microflora, then the use of Bioflora will help to eliminate it. However, it is difficult to identify all allergenic factors. Therefore, taking Bioflora should be started with a small amount of the drug and, in the absence of allergic reactions, gradually increase it to the recommended dose. In very rare cases, with severe symptoms of dyspepsia, the use of Bioflor solution in the first days can increase gas formation and the resulting intestinal pain. In this case, it is advisable to discontinue the drug until the symptoms have ceased or treatment with the drug has been discontinued if these symptoms recur. In case of dysfunctions and diarrhea, against the background of helminthic invasions, parasitic diseases caused by protozoa (amoeba, Giardia, etc.), specific treatment as prescribed by a doctor must be carried out. Use in children Use in children from 6 months of age is allowed. Influence on the ability to drive vehicles and work with mechanisms Does not affect the ability to drive vehicles and work with dangerous mechanisms. Use during pregnancy and lactation The safety of the drug during pregnancy and lactation has not been studied in controlled clinical trials. Interaction with other medicinal products With the simultaneous use of Bioflor and oral antimicrobials, the clinical efficacy of Bioflor is reduced. Storage conditions Store in a place protected from light at a temperature of 2 ° C to 8 ° C. Shelf life 1 year. Do not use after the expiry date stated on the package. Keep out of the reach of children. After opening the bottle, use the drug within 10 days. Holiday conditions Without a prescription. Buy Bioflor oral solution 100ml №1 Price for Bioflor oral solution 100ml №1Instruction for use for Bioflor oral solution 100ml №1
INN | OTHER |
---|---|
The code | 129 952 |
Barcode | 4 814 405 001 663 |
Dosage | 100ml |
Active substance | Escherichia coli |
Manufacturer | Ferein SOAO, RB, Belarus |
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