Name:
Tailolfen Hotpor. d/prep. r-ra d / ingestion in a pack. 15g per pack №12 Main active ingredient Paracetamol + phenylephrine + chlorphenamine Product form powder Composition 1 package contains: paracetamol 325 mg, chlorpheniramine maleate 4 mg, phenylephrine hydrochloride 10 mg; excipients: anhydrous citric acid, tartaric acid, sodium bicarbonate (sodium bicarbonate), anhydrous sodium carbonate, lemon flavor (maltodextrin, flavoring part, gum arabic (E 414), silicon dioxide (E 551) alpha-tocopherol (E 307), sucrose , polyvinylpyrrolidone K30 (Povidone K30), quinoline yellow (E 104)
Description:
White to light yellow powder with lemon flavor May include yellow granules Dosage 15g Indications pain, sore throat, muscle and joint pain, nasal congestion, rhinorrhea Contraindications – hypersensitivity to the ingredients of the drug; – severe diseases of the liver, kidneys, heart, lungs; – angle-closure glaucoma; – diabetes mellitus; – pregnancy and lactation; – children under 12 years of age – concomitant use of MAO inhibitors – alcoholism – deficiency of glucose ozo-6-phosphate dehydrogenase. Use with caution in arterial hypertension, bronchial asthma, thyrotoxicosis, pheochromocytoma, difficulty urinating with prostate adenoma, blood diseases, congenital hyperbilirubinemia (Gilbert, Dubin-Johnson and Rother syndromes). The patient should stop taking MAO inhibitors 2 weeks before starting Tylolfen Hot. Use during pregnancy and lactation Use during pregnancy is contraindicated. Women should stop breastfeeding while taking the drug. Dosing and Administration Tylolfen Hot is taken orally. Assign 1 package with an interval of 6 hours. The recommended maximum daily dose is 4 packets. The contents of the package are dissolved in 160 ml of hot water and drunk immediately. Children: Children 12 years of age and older are given the adult dose. Tailolfen Hot is not recommended for children under 12 years of age. Side effects In most cases, the drug is well tolerated. In rare cases, the following side effects may occur: Blood and lymphatic system disorders – anemia, sulfhemoglobinemia and methemoglobinemia (cyanosis, shortness of breath, heart pain), thrombocytosis, thrombocytopenia. Gastrointestinal disorders – heartburn, nausea, vomiting, dry mouth, epigastric discomfort and pain, hypersalivation, loss of appetite, constipation, diarrhea, flatulence. On the part of the hepatobiliary system – an increase in the activity of liver enzymes, as a rule, without the development of jaundice, hepatonecrosis (dose-dependent effect); Endocrine system disorders – hypoglycemia up to hypoglycemic coma. Immune system disorders – hypersensitivity reactions, anaphylaxis. Nervous system disorders – headache, weakness, dizziness, agitation and disorientation, anxiety, anxiety, sleep disturbance, drowsiness, insomnia, dyskinesias, behavioral changes, irritability or nervousness, tremor, confusion, depression, tingling sensation and heaviness in the extremities, tinnitus, epileptic seizures, coma. Kidney and urinary tract disorders – renal colic, ??? nephritis, urinary retention and difficulty urinating, aseptic pyuria. On the part of the organs of vision – visual impairment and accommodation, dry eyes, mydriasis. Skin and subcutaneous tissue disorders – itching, rash on the skin and mucous membranes (erythema, urticaria), angioedema, erythema multiforme (including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell’s syndrome). Cardiovascular system disorders – tachycardia, reflex bradycardia, shortness of breath, heart pain, increased blood pressure, arrhythmia, with prolonged use in high doses, myocardial dystrophy is possible. Respiratory system disorders – bronchospasm in patients sensitive to acetylsalicylic acid and other NSAIDs. Overdose If an overdose is suspected, the patient should be immediately hospitalized regardless of the severity of the symptoms. Symptoms: paracetamol can have a hepatotoxic effect in case of overdose. For 12-48 hours, there may be an increase in the level of liver enzymes, prolongation of prothrombin time; however, clinical symptoms become apparent 1-6 hours after taking the drug. A total of 10 g of paracetamol may be toxic in adults; when paracetamol is taken by children at a dose of at least 150 mg / kg, a toxic effect may not be observed. Early symptoms of hepatotoxicity are nausea, vomiting, increased sweating, and malaise. Treatment: it is recommended to prescribe acetylcysteine as soon as possible after an overdose of paracetamol, without waiting for the results of paracetamol in the blood, as well as gastric lavage and induction of vomiting. Monitoring may also include the determination of the content of paracetamol in plasma 4 hours after taking an excess dose. Perform liver tests at 24-hour intervals for at least 96 hours after an overdose if paracetamol plasma levels indicate hepatotoxicity. Since the metabolism of paracetamol in children differs from that in adults, cases of severe toxicity, including death, are rare. If the overdose exceeds 150 mg/kg of weight, then it is necessary to determine the concentration of paracetamol in the blood, it is recommended to wash the stomach and induce vomiting, the appointment of acetylcysteine. If the determination of the plasma concentration of paracetamol is not possible, and the total dose exceeds 150 mg / kg of body weight, then treatment with acetyl cysteine is also started. The toxicity of chlorpheniramine becomes apparent several hours after ingestion; treatment should be initiated as described for antihistamine/anticholinergic overdose. An overdose due to the action of phenylephrine and chlorpheniramine maleate can cause increased sweating, psychomotor agitation or CNS depression, headache, dizziness, drowsiness, impaired consciousness, heart rhythm disturbances, tachycardia, extrasystole, tremor, hyperreflexia, convulsions, nausea, vomiting, irritability, anxiety, increased blood pressure. With an overdose of chlorpheniramine maleate, atropine-like symptoms may occur: mydriasis, photophobia, dry skin and mucous membranes, fever, intestinal atony. CNS depression is accompanied by respiratory disorders and disorders of the cardiovascular system (decrease in heart rate, decrease in blood pressure to vascular insufficiency). In case of overdose, symptomatic therapy is necessary. Interaction with other drugs When used simultaneously with paracetamol, the following types of interactions can be observed: – the rate of absorption of paracetamol can be increased by metoclopramide and domperidone, decreased by cholestyramine; – may slow down the excretion of antibiotics from the body; – barbiturates and ethanol can increase the hepato- and nephrotoxicity of paracetamol, barbiturates reduce the antipyretic effect; – anticonvulsants (phenytoin, barbiturates, carbamazepine), isoniazid can increase the hepatotoxic effect of paracetamol; – tetracycline increases the risk of anemia and methemoglobinemia caused by paracetamol; – the effect of indirect anticoagulants may be enhanced with an increased risk of bleeding with prolonged regular use of paracetamol; – may reduce the effectiveness of diuretics; – Antacids and food reduce the absorption of paracetamol. The simultaneous use of Tylolfen Hot with the following drugs can significantly increase the inhibitory effect of chlorpheniramine maleate: hypnotics, barbiturates, sedatives, antipsychotics; tranquilizers, anesthetics, narcotic analgesics, ethanol-containing drugs. Chlorpheniramine enhances the anticholinergic effect of atropine, antispasmodics, tricyclic antidepressants, antiparkinsonian drugs. Phenylephrine hydrochloride can cause the development of a hypertensive crisis or arrhythmia when used simultaneously with other adrenomimetics or MAO inhibitors, cause severe hypertension when combined with indomethacin and bromocreptine. Rauwolfia alkaloids reduce the therapeutic effect of phenylephrine hydrochloride. Precautions Avoid simultaneous use with other drugs intended for the symptomatic treatment of colds and flu, drugs containing paracetamol. This medicinal product is not recommended for concomitant use with sedative-hypnotics or drinks containing alcohol due to an increased risk of hepatotoxicity. This medicinal product contains paracetamol, which, due to hepatotoxicity, must not be used longer or in higher doses than recommended in the Dosage and Administration section. Long-term use can lead to severe liver complications such as cirrhosis. Acute or chronic overdose can lead to severe liver damage and, in rare cases, death. Patients with liver disease or liver infections such as viral hepatitis should consult their doctor before using this medicine. Patients with mild to moderate hepatic insufficiency (<9 points on the Child-Pugh scale) should use this drug with caution. During the use of paracetamol in therapeutic doses, an increase in ALT is possible. Patients with kidney disease should consult their doctor before using this drug, as dose adjustment may be required. In case of severe renal insufficiency (CC < 10 ml / min), the doctor should evaluate the risk / benefit ratio before starting the drug. Dose adjustment and continuous monitoring are required. Long-term use of paracetamol, especially in combination with other analgesics, can lead to irreversible kidney damage and the risk of kidney failure. The use of paracetamol in patients suffering from Gilbert's syndrome may lead to more severe hyperbilirubinemia and clinical symptoms such as jaundice. Therefore, paracetamol should be used with caution in these patients. The drug should be prescribed by a doctor only after assessing the risk / benefit ratio in the following cases: arterial hypertension; epilepsy; BPH; heart rhythm disturbances; urination disorders. If, on the recommendation of a doctor, the drug is used for a long period, it is necessary to monitor the functional state of the liver and the picture of peripheral blood. Please note that 1 sachet (1 dose) contains sucrose. Do not exceed the indicated dose. Elderly people should use the drug with caution. Storage conditionsKeep in a place protected from light at a temperature not exceeding 25°C. Keep away from children. Buy Tylolfen Hot powder for oral solution in bags 15g #12 Price for Tylolfen Hot powder for oral solution in bags 15g #12 Instructions for use for Tylolfen Hot powder for oral solution in bags 15g #12
Tylolfen Hot powder for solution for oral administration in bags 15g №12
$32.00
SKU: 74668
Category: Medicines for colds and flu
INN | PARACETAMOL + PHENYLEPHRINE + CHLORPHENAMIN + CAFFEINE |
---|---|
The code | 74 668 |
Barcode | 8 699 540 250 024 |
Dosage | 15g |
Active substance | Paracetamol, phenylephrine hydrochloride, chlorphenamine maleate |
Manufacturer | Nobel Ilach Sun. wee tick. A.S., Turkey |
Importer | IOOO Interfarmaks 223028 Minsk region, Minsk district, Zhdanovichsky s / s, ag. Zhdanovichi, st. Star, 19a-5, room. 5-2 |
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