Totem solution for oral administration in ampoules 10ml №20

Name:
Totem amp. 10 ml №20 Storage conditions The drug should be stored out of the reach of children at a temperature not exceeding 25°C. Expiration date from the date of manufacture2 years
Description:
of goodsSolution for oral administration dark brown, with a characteristic odor; there may be some sediment. Pharmacological action Combined antianemic drug. Contains iron, which is necessary for the synthesis of heme, which is part of hemoglobin, myoglobin, flavoproteins, iron-ferritin and iron-transferrin complexes, various enzymes; participates in a number of redox reactions. Copper and manganese are microelements and are cofactors of some enzymes. The absorption of trace elements is the more intense, the greater the iron deficiency in the body. When taking the drug, there is a gradual regression of the clinical and laboratory symptoms of anemia. Pharmacokinetics Pharmacokinetics Absorption of iron and other trace elements occurs mainly in the duodenum and upper jejunum. Indications for use Treatment and prevention of iron deficiency anemia in adults and children from 3 months of age caused by various causes: bleeding; increased need for iron (pregnancy); insufficient intake of iron from food or impaired absorption. Use during pregnancy and lactation during pregnancy and lactation according to indications in recommended doses. Special instructions Monitoring the effectiveness of treatment should be carried out no earlier than 3 months after the start of treatment. Excessive consumption of tea inhibits iron absorption. In order to avoid darkening of the enamel of the teeth, a long stay of the drug solution in the oral cavity should be avoided. Patients with diabetes should take into account that 10 ml of the drug contains 3 g of sucrose. 1 ampoule of the drug contains 1/4 XE, in the maximum daily dose (in 4 ampoules of the drug) 1 XE. During treatment with iron preparations, patients may experience black stools, however, this does not require medical intervention. During treatment with iron preparations, a fecal occult blood test may give a false positive result. Influence on the ability to drive vehicles and control mechanisms There is no evidence of a negative effect of the drug on the ability to drive vehicles and other mechanisms. With caution (Precautions) With caution, the drug should be prescribed for diabetes mellitus. Contraindications anemia not associated with iron deficiency; hemochromatosis, hemosiderosis; thalassemia; peptic ulcer of the stomach and duodenum in the acute phase; lead intoxication; intoxication with copper or manganese, Wilson-Konovalov’s disease; sucrase / isomaltase deficiency, fructose intolerance, malabsorption syndrome of glucose galactose; children’s age up to 3 months; hypersensitivity to the components of the drug. Dosage and administration For the treatment of anemia, adults are prescribed the drug at the rate of 100-200 mg of iron (2-4 amps) / day; children older than 3 months – at the rate of 5-7 mg / kg body weight / day in 2-4 doses. The use of the drug is carried out under the control of the iron content in the blood serum, the total iron-binding capacity of the serum before the start of treatment and thereafter at intervals of 1 time in 2 months. For prophylactic purposes, adults and pregnant women (starting from the 4th month of pregnancy) are prescribed 50 mg (1 amp.) / day. For children, depending on age, the drug is prescribed at a dose of 1/4 to 1/2 of the daily therapeutic dose of adults. The duration of treatment is determined individually. The average duration of taking the drug is from 3 to 6 months (until the restoration of iron stores in the body). Rules for the use of the drug Shake well before use. You should tear off a piece of cardboard from the pack along the dotted line, bend it in half to safely break the tip of the ampoule. Break the ampoule on both sides, pour the contents of the ampoule into a glass, dissolve in plain or sweetened water. Take orally, before meals. Overdose Symptoms: weakness, hyperthermia, convulsions, nausea, vomiting, constipation, diarrhea, epigastric pain. Cases of necrosis of the walls of the gastrointestinal tract and shock are described. Treatment: gastric lavage with 1% sodium bicarbonate solution (baking soda). With a serum iron concentration of more than 5 μg / ml, deferoxamine is administered intravenously slowly: for children – 15 mg / kg / h, for adults – 5 mg / kg / h (up to 80 mg / kg / day); with mild poisoning in / m: children – 1 g every 4-6 hours, adults – 50 mg / kg (up to 4 g / day); carry out symptomatic therapy; in the event of shock, anti-shock therapy is carried out. Side effect On the part of the digestive system: staining of feces black (is the norm), heartburn, nausea, vomiting, diarrhea, constipation, pain in the epigastric region, darkening of tooth enamel. Other: allergic reactions. Composition 1 amp. iron (elemental, in the form of iron gluconate dihydrate) 50 mg manganese (elemental, in the form of manganese gluconate) 1.33 mg copper (elemental, in the form of copper gluconate) 700 mcg Excipients: glycerol – 2.52 g, dextrose (glucose) – 80 mg, sucrose – 3 g, anhydrous citric acid – 27.4 mg, sodium citrate dihydrate – 30 mg, sodium benzoate – 20 mg, polysorbate 80 – 24 mg, caramel color TPS (E150c) – 50 mg, tutti-frutti flavor – 20 µl , purified water – up to 10 ml. Interaction with other drugs Simultaneous use of the drug Totem leads to a decrease in the absorption of bisphosphonates, ciprofloxacin, tetracyclines when taken orally. Salts, oxides and hydroxides of magnesium, aluminum and calcium disrupt the absorption of iron salts. Totem® should be taken no earlier than 2 hours after taking these drugs. You can not combine the drug with other iron preparations, incl. administered parenterally. Release formSolution for oral administration of dark brown color, with a characteristic odor; there may be some sediment. 1 ml 1 amp. iron (elemental, in the form of iron gluconate dihydrate) 5 mg 50 mg manganese (elemental, in the form of manganese gluconate) 133 mcg 1.33 mg copper (elemental, in the form of copper gluconate) 70 mcg 700 mcg Excipients: glycerol – 2.52 g, dextrose ( glucose) – 80 mg, sucrose – 3 g, anhydrous citric acid – 27.4 mg, sodium citrate dihydrate – 30 mg, sodium benzoate – 20 mg, polysorbate 80 – 24 mg, caramel color TPS (E150c) – 50 mg, tutti flavor -frutti” – 20 µl, purified water – up to 10 ml. 10 ml – two-ended yellow glass ampoules type III (10) – cardboard pallets (2) – cardboard packs. Buy Totem oral solution in ampoules 10ml №20