Sanorin emulsion for intranasal use 0.1% 10ml №1

NameSanorin emulsion. Type of drugMedication. Organs and systems Nasal cavity, nasopharynx. PurposeOtitis media, sinusitis, allergic rhinitis, runny nose, infectious rhinitis, acute and chronic sinusitis, eustachitis. Indications for use Reducing swelling of the nasal mucosa, including acute rhinitis of various etiologies, sinusitis, laryngitis, eustachitis, otitis media (as an additional remedy); – to reduce swelling of the mucous membranes of the nose, nasopharynx and paranasal sinuses during diagnostic and therapeutic procedures. Contraindications Hypersensitivity to naphazoline or one of the components of the drug; age up to 15 years; atherosclerosis; arterial hypertension; tachycardia; thyrotoxicosis; chronic atrophic rhinitis; severe eye diseases; angle-closure glaucoma; diabetes; simultaneous use of monoamine oxidase inhibitors (MAO) and a period of up to 14 days after the end of their use. Composition 10 ml of the drug contains: active substance: naphazoline nitrate 0.010 g; excipients: boric acid 0.300 g, ethylenediamine qs (about 0.0004 g), cetyl alcohol 0.004 g, methyl paraben 0.010 g, eucalyptus oil 0.00025 g, polysorbate 80 0.055 g, cholesterol 0.008 g, liquid paraffin (vaseline oil) 1.150 g, purified water up to 10,000 ml. Active ingredient Nafazolin. Dosage 0.1% Dosage and administrationAdults and children over 15 years of age. Intranasally. 1-3 drops of the drug in each nasal passage 3-4 times a day. The duration of treatment is not more than 5-7 days. If necessary, treatment can be resumed after a few days. The drug is instilled into each nasal passage with the head slightly thrown back. When instilled into the left nasal passage, the head should be tilted to the right, and when instilled into the right nasal passage, to the left. Side effects At recommended doses, naphazoline is generally well tolerated. On the part of the respiratory system: dryness of the nose, reactive hyperemia of the mucous membrane of the nasal cavity, irritation and swelling of the mucous membrane of the nasal cavity when used for more than 1 week, atrophic rhinitis. From the nervous system: irritability, headache, tremor. From the side of the cardiovascular system: increased blood pressure (BP), hot flashes, tachycardia. Other: increased sweating. Pharmacological actionNafazolin refers to alpha2-adrenergic agonists with a direct stimulating effect on the alpha-adrenergic receptors of the sympathetic nervous system. When administered intranasally, it has a rapid, pronounced and prolonged vasoconstrictor effect on the vessels of the mucous membranes of the nose, nasopharynx and paranasal sinuses – it reduces swelling and hyperemia, which improves the patency of the nasal passages and facilitates nasal breathing. The therapeutic effect occurs, as a rule, within 5 minutes after administration and lasts for 4-6 hours. Pharmacological group Anticongestive agent – alpha-adrenergic agonist. Release form Drops. Method of application/administration Nasal. The minimum age of use is from 15 years. Storage conditionsStore at a temperature of 10 to 25 ° C, protected from light. Keep out of the reach of children. Overdose Symptoms: irritability, headache, tremor, palpitations, tachycardia and increased blood pressure. Possible symptoms of an overdose may include nausea, cyanosis, fever, convulsions, acute heart failure, pulmonary edema, respiratory failure, mental disorders, bradycardia, weakness, drowsiness, decreased body temperature, increased sweating, decreased blood pressure, and coma is extremely rare. Treatment: symptomatic. Application during pregnancy and lactation There is no data on the penetration of naphazoline through the placental barrier, as well as into breast milk. In this regard, when prescribing naphazoline, it is necessary to evaluate the ratio of benefit to the mother and risk to the fetus and infant. Influence on the ability to drive vehicles and mechanisms At the recommended dose, the drug does not affect the ability to drive vehicles or control mechanisms section “Side Effects”). The use of the drug for more than 5 days can lead to swelling and swelling of the nasal mucosa, nasopharynx and sinuses. Long-term use of the drug leads to damage to the mucous membrane, a decrease in ciliary activity and irreversible disorders leading to the occurrence of chronic atrophic rhinitis. Interaction With the simultaneous use of naphazoline with MAO inhibitors, tricyclic antidepressants, including maprotiline, and even a few days after the end of their use, an increase in blood pressure is possible, due to the release of deposited catecholamines under the action of naphazoline. When conducting general anesthesia with the use of anesthetics that increase the sensitivity of the myocardium to sympathomimetics (halothane), especially in patients with bronchial asthma, care should be taken. Buy Sanorin emulsion for intranasal use 0.1% 10ml №1