Panzinorm forte 20000 tablets p/o №10×3

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Panzinorm forte 20000 tablets coated. in bliss. in pack. №10×3
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Smooth, round, biconvex, flavored, white or light gray film-coated tablets. The main active ingredient Pancreatin Release form tablets Dosage The dose and duration of therapy is determined individually depending on the age and degree of pancreatic insufficiency. Adults Panzinorm® forte 20,000 is recommended to take (in the absence of other prescriptions) at the beginning of treatment, 1 table. 3 times a day, during each main meal. It is possible to take Panzinorm® forte 20,000 tablets while taking a light snack. If necessary, a single dose is increased by 2 times. The average daily dose is 1-2 tablets. 3 times. Special instructions The tablet shell prevents damage to the oral mucosa by active pancreatic enzymes and protects the enzymes from the effects of gastric juice. Tablets should be swallowed whole and not chewed. The safety of use in children has not been established. Special information about the excipients of the drug Panzinorm forte 20,000 contains lactose. Patients with rare hereditary problems of galactose intolerance, lactase enzyme deficiency or glucose-galactose malabsorption should not take the drug. Pharmacological action Digestive aids, including enzymatic agents. enzyme preparations. Pharmacodynamics Panzinorm forte 20,000 restores the deficiency of pancreatic enzymes, increases catabolic metabolism and improves the clinical picture of maldigestion. The drug increases the absorption of all types of food, improves the nutrition of the patient, prevents or reduces steatorrhea and symptoms caused by maldigestion. Pancreatin helps to reduce pain in chronic pancreatitis. Pharmacokinetics Enzymes are natural compounds that provide food digestion. The film coating of the tablets protects the active enzymes from the effects of gastric juice. Enzymes are proteins, they are synthesized in the body, inactivated and degraded, mainly in the intestine by autolysis and proteolysis. A small part of the digestive enzymes is excreted in the feces. Indications for use Insufficiency of the exocrine function of the pancreas. Method of administration and doses The dose is selected individually. Treatment begins with low doses: 1 tablet three times a day during the main meals. If symptoms of pancreatic enzyme deficiency persist, the dosage may be gradually increased. Usually a dose of 1-2 tablets during the main meals (3 times a day) is sufficient. If necessary, 1 tablet may be taken with light meals. The dosage may be higher, however, the lowest dose necessary to prevent symptoms should be taken, which is especially important for patients with cystic fibrosis. Children usually need smaller doses. Use during pregnancy and lactation There are no data on harmful effects during pregnancy and lactation. Enzymes are not absorbed from the gastrointestinal tract, however, a risk cannot be ruled out. In accordance with the FDA classification during pregnancy, pancreatin is classified as category C. Use is indicated if the potential benefit justifies the risk. Interaction with other drugs Pancreatic enzymes interfere with the absorption of folic acid. With the simultaneous use of drugs that have a similar effect (such as bicarbonate and cimetidine), and with long-term treatment with high doses of pancreatic enzymes, the concentration of folate in the blood serum should be periodically monitored and / or compensate for the lack of folic acid. Pancreatic enzymes may reduce the effectiveness of acarbose and miglitol. Pancreatic enzymes may reduce iron absorption, but this interaction has not been shown to be clinically significant. The acid-resistant shell of Panzinorm forte 20,000 tablets is destroyed in the duodenum. If the pH in the duodenum is significantly reduced, then pancreatic enzymes are not released in time. Concomitant treatment with H2 receptor inhibitors and proton pump inhibitors enhances the action of pancreatic enzymes, which allows you to prescribe lower doses of Panzinorm forte 20,000. Patients with acute pancreatitis or exacerbation of chronic pancreatitis should not take Panzinorm forte 20,000. Do not prescribe the drug to children under 15 years of age suffering from cystic fibrosis. Composition 1 tablet contains porcine pancreatin with enzymatic activity of lipase 20,000 IU EF, amylase 12,000 IU EF, protease 900 IU EF. Excipients: lactose monohydrate, microcrystalline cellulose, crospovidone, anhydrous colloidal silicon dioxide, magnesium stearate, hypromellose, methacrylic acid and ethyl acrylate copolymer (1: 1), triethyl citrate, titanium dioxide (E 171), talc, simethicone – emulsion, flavoring vanillin 54 286 C, bergamot flavor 54 253 T, macrogol 6000, carmellose sodium and polysorbate 80. Overdose There is no evidence that overdose causes systemic intoxication. Symptoms. Overdose can cause nausea, vomiting, diarrhea, hyperuricemia and hyperuricosuria, perianal irritation, and, exclusively in patients with cystic fibrosis, fibrous colonopathy. Treatment. If these effects occur, you should stop taking the drug, drink plenty of water and consult a doctor. Side effects Like all medicines, Panzinorm forte 20,000 can cause side effects in some cases. Rare adverse reactions (in 1-10 patients out of 10,000) include nausea, vomiting, abdominal pain, soft stools or constipation, perioral or perianal skin irritation. These reactions occur when taking high doses of the drug. As a rule, they are mild and do not require discontinuation of treatment. Also, when using high doses of the drug, hyperuricemia and hyperuricosuria can be observed. Very rare adverse reactions (in less than 1 patient in 10,000) include allergic reactions and fibrous colonopathy. In the event of a rash, itching, difficulty breathing, bloating, abdominal pain or intestinal cramps, stop taking the drug and consult a specialist. If you experience any of the side effects described, or any side effects not listed in this leaflet, please tell your doctor. Storage conditions The medicinal product does not require special storage conditions. Keep out of the reach of children. Buy Panzinorm forte 20000 tablets p/o No. 10×3 Price for Panzinorm forte 20000 tablets p/o No. 10×3