Name:
Nicergolin-LF caps. 10 mg in a cell. pack No. 10×5
Description:
Hard gelatin capsules No. 1 of a cylindrical shape with hemispherical ends of white color. The main active ingredient is Nicergoline. Release formCapsules. Dosage 10mg Indications Nicergoline-LF is indicated for the symptomatic treatment of mild to moderately severe dementia for the correction of cognitive and behavioral disorders. Method of administration and doses For oral administration. 5 mg – 10 mg three times a day with the same intervals between doses for a long period of time (up to several months). In vascular dementia, the use of 30 mg 2 times a day is indicated (with every 6 months it is recommended to consult a doctor about the advisability of continuing therapy). Dose, duration of therapy and route of administration depend on the nature of the disease. In patients with impaired renal function (serum creatinine ≤ 2 mg/dl), nicergoline is recommended at lower therapeutic doses. Use during pregnancy and lactation There are no special studies on the use during pregnancy. Nicergoline-LF should be used only if clearly needed and under the direct supervision of a physician. At the time of taking the drug, it is necessary to abandon breastfeeding, because nicergoline and its metabolic products penetrate the mother’s milk. Influence on the ability to drive vehicles and control mechanisms Despite the fact that the drug improves the reaction and concentration of attention, its effect on the ability to drive a car and use complex equipment has not been specifically studied. Care should be taken, given the nature of the underlying disease. Precautions In therapeutic doses, nicergoline, as a rule, does not affect blood pressure, however, in patients with arterial hypertension, it can cause a gradual decrease. The drug acts gradually, so it should be taken for a long time, while the doctor should periodically (at least every 6 months) evaluate the effect of treatment and the advisability of continuing it. Nicergoline-LF should be used with caution in patients with a history of hyperuricemia or gout and / or in combination with drugs that interfere with the metabolism or excretion of uric acid. Against the background of the use of drugs containing ergot derivatives, including nicergoline, there is a risk of developing fibrosis and ergotism. Interaction with other drugs Nicergoline may enhance the effect of antihypertensive drugs. Nicergoline is metabolized under the influence of cytochrome CYP450 2D6, therefore, the possibility of its interaction with drugs that are metabolized with the participation of the same enzyme is not excluded. Contraindications Recent myocardial infarction, acute bleeding, severe bradycardia, orthostatic dysregulation, hypersensitivity to nicergoline or other components of the drug. Composition One capsule of Nicergoline-LF contains: Active ingredient: nicergoline – 10 mg. Excipients: microcrystalline cellulose, magnesium stearate, sodium carboxymethylcellulose, calcium hydrogen phosphate dihydrate. The composition of the shell of a gelatin capsule containing nicergoline 10 mg: Gelatin, titanium dioxide E-171, purified water. Overdose Symptoms: transient marked decrease in blood pressure. Treatment: special treatment is usually not required, it is enough for the patient to take a horizontal position for several minutes. In exceptional cases, with a sharp violation of the blood supply to the brain and heart, it is recommended to administer sympathomimetic drugs under constant monitoring of blood pressure. Side effects When taking the drug, there is a possibility of developing adverse reactions, which are classified by organ systems and by frequency of occurrence: very often> 1/10, often from> 1/100 to <1/10, infrequently from> 1/1000 to <1/100 , rarely from ? 1/10,000 to < 1/1,000, very rare < 1/10,000, not known (frequency cannot be determined from current data). Rarely: From the side of the cardiovascular system: a pronounced decrease in blood pressure (BP), mainly after parenteral administration; From the gastrointestinal tract: dyspeptic phenomena; From the side of the central nervous system: dizziness, drowsiness or insomnia; From the skin and subcutaneous tissues: skin rashes; General disorders: sensation of heat. It is possible to increase the concentration of uric acid in the blood, and this effect does not depend on the dose and duration of therapy. Side effects are usually mild or moderate. Storage conditions In a place protected from moisture and light at a temperature not exceeding 25 ° C. Keep out of the reach of children. Buy Nicergolin-LF capsules 10mg No. 10x3 Price for Nicergolin-LF capsules 10mg No. 10x3
INN | NICERGOLIN |
---|---|
The code | 81 176 |
Barcode | 4 812 608 005 921 |
Dosage | 10mg |
Active substance | Nicergoline |
Manufacturer | Lekpharm, Belarus |
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