Mildrocard solution for intravenous injection 100mg/ml in ampoules 5ml №5×2

Name Mildrocard solution for intravenous administration 100 mg/ml in 5 ml amp. Main active ingredient Meldonium (trimethylhydrazinium propionate) Release form Solution Dosage 100 mg/ml Pharmacological action The active substance of MILDROCARD is meldonium. Meldonium is a structural analogue of gamma-butyrobetaine, a substance found in every cell of the human body. Under conditions of increased load, MILDROCARD restores the balance between the delivery and demand of cells for oxygen, eliminates the accumulation of toxic metabolic products in cells, protecting them from damage; It also has a tonic effect on the central nervous system. As a result of its use, the body acquires the ability to withstand the load and quickly restore energy reserves. Due to these properties, MILDROCARD is used to treat various disorders of the cardiovascular system, blood supply to the brain, as well as to increase physical and mental performance and eliminate functional disorders of the nervous system. Method of administration and doses MILDROCARD is administered intravenously. The dose, mode of administration and duration of the course of treatment will be determined by your attending physician, depending on the indications and your condition. MILDROCARD can have a stimulating effect, so it is recommended to administer the drug in the morning. Dose and duration of treatment As part of complex therapy, 0.5-1.0 g of meldonium (5-10 ml of MILDROCARD) is administered intravenously per day, at a time or by dividing the dose into 2 injections for 10-14 days, followed by switching to oral dosage form of meldonium. The general course of treatment is 4-6 weeks. The course of treatment can be repeated 2-3 times a year. Use in children and adolescents Due to the lack of data on the efficacy and safety of the use of meldonium in children and adolescents, the use of MILDROCARD in children and adolescents under 18 years of age is contraindicated. If you have taken MILDROCARD more than you should have In case of an overdose of MILDROCARD, you may experience a decrease in blood pressure, accompanied by headache, palpitations, dizziness and general weakness. If you have injected more MILDROCARD than you should, you should consult a doctor. If you miss an injection of MILDROCARD If you miss an injection of MILDROCARD, the drug should be given as soon as possible. But if it is almost time for the next injection, you must enter the usual dose of the drug. Do not take a double dose to make up for a missed one. If you stop using MILDROCARD early When you stop using MILDROCARD early, no adverse effects were observed. If you have any questions about the use of the drug, contact your doctor. Use during pregnancy and lactation If you are pregnant or breastfeeding, think you may be pregnant, or plan to become pregnant, tell your doctor before starting treatment with MILDROCARD. MILDROCARD is contraindicated during pregnancy and lactation. If the mother needs to use MILDROCARD, breast-feeding should be discontinued. Driving and using machines There are no data on the adverse effects of MILDROCARD on the ability to drive and use machines. Precautions: Talk to your doctor before using MILDROCARD if you have ever had liver or kidney disease. In this case, you need regular monitoring of the function of these organs. Interactions with other drugs Talk to your doctor if you are taking, have recently taken or may start taking any other medicines. This applies to any herbal preparations and over-the-counter preparations. Talk to your doctor if you are taking: nitroglycerin, nifedipine, beta-blockers, or other drugs that lower blood pressure or dilate blood vessels. The use of MILDROCARD in combination with these drugs may cause an increase in heart rate and a decrease in blood pressure. Cyclophosphamide or ifosfamide – MILDROCARD may increase the negative effect of these drugs on the heart. Other drugs that contain meldonium – in this case, the risk of adverse reactions increases. MILDROCARD can be combined with cardiac glycosides, drugs that are used to treat angina pectoris (severe pain in the heart area), heart rhythm disturbances, reduce blood viscosity and reduce the risk of blood clots, diuretics and drugs that eliminate bronchospasm. MILDROCARD in combination with lisinopril can be used to treat chronic heart failure. MILDROCARD in combination with orotic acid can be used to repair damage that occurs when blood circulation is disturbed and its subsequent renewal. MILDROCARD in combination with iron preparations can be used to treat anemia caused by iron deficiency. MILDROCARD may be used in combination with azidothymidine and other drugs for the treatment of AIDS. MILDROCARD reduces the toxic effects of indinavir on the heart, efavirenz on the nervous system. MILDROCARD with food, drink and alcohol MILDROCARD does not interact with food, drink or alcohol. Contraindications Do not use the drug If you have one of the following contraindications: Allergy to meldonium; Increased intracranial pressure; Serious problems with the liver and / or kidneys; Children under 18 years of age (safety and effectiveness of use have not been established); You are pregnant or think you might be pregnant; you are breast-feeding. If you are not sure if any of the above apply to you, tell your doctor before taking MILDROCARD. Composition The active substance of the drug MILDROCARD is meldonium. 1 ml of solution contains 100.0 mg of meldonium. Each ampoule contains 500.0 mg of meldonium. Excipient: water for injections. Side effects Like all medicines, MILDROCARD can cause side effects, although not everybody gets them. The following adverse reactions may occur: Common (may affect up to 1 in 10 people): allergic reactions, headaches, dyspepsia (indigestion). Rare (may affect up to 1 in 1,000 people): hypersensitivity, allergic dermatitis, urticaria, angioedema, anaphylactic reaction; spontaneously occurring sensations of burning, tingling, crawling; trembling of the fingers; numbness of various parts of the body and loss of skin sensitivity; tinnitus, dizziness, gait disturbances, lightheadedness, loss of consciousness; heart rhythm disturbances, palpitations, chest discomfort/chest pain; increased/lower blood pressure, excessive increase in blood pressure, reddening of the skin, pallor of the skin; sore throat , cough, shortness of breath, difficulty breathing; metallic taste in the mouth, loss of appetite, gagging, nausea, vomiting, accumulation of gases, diarrhea, abdominal pain; rashes, itching; back pain, muscle weakness, muscle spasms; frequent urination; general weakness, trembling, swelling, swelling of the face, swelling of the legs, sensation of heat, sensation of cold, cold sweat; abnormal electrocardiogram, increased heart rate, increased blood eosinophils. Reporting of adverse reactions If you experience any adverse reactions, consult with a doctor. This recommendation applies to any possible adverse reactions, including those not listed in the package insert. You can also report adverse reactions to the information database on adverse reactions (actions) to drugs, including reports of drug inefficiencies identified in the state (UE “Center for Expertise and Testing in Health Care”, website rceth.by). By reporting adverse reactions, you help to get more information about the safety of the drug. Storage conditions Keep the drug out of the reach of children. Store the drug in a place protected from light at a temperature not exceeding 25 ° C. Do not freeze. Do not use the drug after the expiration date indicated on the package. The expiry date is the last day of the month. Shelf life – 3 years. Do not dispose of the drug down the drain or with household waste. Ask your pharmacist how to dispose of drugs you no longer need. These measures will help protect the environment. Buy Mildrocard solution for intravenous injection 100mg/ml in ampoules 5ml No. 5×2 Price for Mildrocard solution for intravenous injection 100mg/ml in ampoules 5ml No. 5×2 5×2