Deep Relief Gel 100g №1

Name:
Deep Relief Gel (5g + 3g) 100g in tubes 100g in pack No. 1
Description:
Transparent gel with menthol smell Main active ingredient Ibuprofen + menthol Product formGel for external use. 15 g, 50 g or 100 g in aluminum tubes. Each tube with instructions for use in a pack of cardboard. Dosage Externally. For adults. A small amount of gel (3-5 cm) is applied in a thin layer to the painful area and rubbed lightly. Hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract, severe liver and kidney dysfunction, chronic heart failure, bronchial asthma, old age. Pharmacological action Other topical agents for joint and muscle pain. ATX code: M02AX10 Ibuprofen inhibits the synthesis of prostaglandins, has anti-inflammatory and analgesic effects. Menthol, when applied topically, has a distracting effect and causes flushing of the skin. It helps to reduce pain in muscles, tendons and joints. Menthol acts on the nerve endings in the skin. The bioavailability of ibuprofen in the form of a gel for external use is about 5% compared with oral administration. The systemic concentration of ibuprofen reaches a maximum of about 0.6 μg / ml two hours after the use of the drug. Levomenthol, which is absorbed through the skin, enters the liver. Metabolism of levomenthol occurs in the liver by hydroxylation and then conjugation with glucuronide. Excretion of metabolic products of levomenthol is carried out by the kidneys. Indications for use Local symptomatic treatment of muscle and joint pain, swelling in light traumatic injuries: sprains, bruises, sports injuries. It is used in the complex treatment of pain in rheumatism. Dosage and administration Externally. For adults. A small amount of gel (3-5 cm) is applied in a thin layer to the painful area and rubbed lightly. Repeat as needed up to 3 times a day, observing an interval of at least 4 hours between each application. The duration of the use of the drug without consulting a doctor is not more than 10 days. If longer use is needed, consult your doctor. Always wash your hands after using Deep Relief unless they are being treated. Use during pregnancy and lactation The safety of ibuprofen during pregnancy has not been sufficiently studied. Animal studies with oral ibuprofen showed no teratogenic effects. When sufficient systemic concentrations of ibuprofen were reached, untimely closure of the ductus arteriosus (ductus arteriosus), an increased risk of postpartum hemorrhage in the mother and newborn, and edema in the pregnant woman were observed. The use of Deep Relief is contraindicated during pregnancy. Ibuprofen and its metabolites are excreted in breast milk. The use of Deep Relief is contraindicated during breastfeeding. Precautions: Before using the drug, you should consult your doctor if you have kidney disease. The gel should be applied to intact skin, avoiding contact with open wounds. After application, do not apply an occlusive (airtight) dressing! Do not apply the drug to inflamed skin. If a rash and irritation of the skin appear during the use of the drug, the use of the drug should be discontinued. Do not allow the drug to come into contact with the eyes and mucous membranes. With prolonged use of large amounts of the drug, there is a risk of developing systemic side effects. Oral ibuprofen may aggravate existing kidney failure or exacerbate peptic ulcers. Patients with a history of impaired renal function or peptic ulcer should consult a physician before taking Deep Relief. Deep Relief contains ibuprofen as an active ingredient, which is a cyclooxygenase inhibitor and may affect fertility if administered systemically. Deep Relief is not recommended for women who have problems getting pregnant or who are undergoing fertility testing. Side effects can be reduced by using the lowest effective dose for the shortest possible duration of treatment. If during the use of the drug any side effects develop, there is no improvement in the condition, or if the condition worsens, you should consult a doctor. This medicinal product contains propylene glycol, which may cause skin irritation. Deep Relief should not be used in children under 18 years of age. Interactions with other drugs Concomitant use of aspirin or other non-steroidal anti-inflammatory drugs may increase the risk of unwanted side effects. The drug may enhance the effect of drugs that cause photosensitivity. Clinically significant interactions with other drugs have not been described. Contraindications Hypersensitivity to ibuprofen or other components of the drug; bronchial asthma provoked by taking acetylsalicylic acid or other NSAIDs; exudative dermatitis, eczema, infected skin lesions, burns; pregnancy, lactation, children’s age (up to 18 years), violation of the integrity of the skin. Simultaneous use on the same area of the skin with other topical drugs is contraindicated. Composition 1 g of gel contains: Active substances: ibuprofen – 50 mg levomenthol (menthol) – 30 mg Excipients: purified water – 445 mg denatured ethanol 96% – 300 mg propylene glycol – 100 mg diisopropanolamine – 55 mg carbomer – 20 mg Overdose When applied topically, an overdose is unlikely. Symptoms caused by ibuprofen: nausea, headache, drowsiness, arterial hypotension. Treatment is symptomatic. Electrolyte balance correction is shown. Side effects Local skin reactions: rash, itching, urticaria, dry skin, redness, burning, contact dermatitis. Systemic side effects associated with ibuprofen: non-specific allergic and anaphylactic reactions; hypersensitivity reactions from the respiratory tract, including asthma, exacerbation of bronchial asthma, bronchospasm and shortness of breath, which may occur in patients suffering from bronchial asthma or allergic diseases at the time of using the drug or have a history of these diseases; various disorders of the skin (rash, itching, urticaria, purpura, Quincke’s edema, rarely bullous dermatoses (toxic epidermal necrolysis, erythema multimorphism), photosensitivity. Other systemic adverse reactions are associated with the penetration of ibuprofen through the skin and depend on the amount of gel used, the magnitude the treated surface, the degree of skin integrity, the duration of treatment and the use of an occlusive dressing.Very rarely, with topical application of ibuprofen, abdominal pain, dyspepsia and renal failure develop.Storage conditionsStore at a temperature not exceeding 25 ° C. Keep out of the reach of children. gel 100g No. 1 Price for Deep Relief Gel 100g No. 1