Carveland tablets 6.25mg №10×3

Name Carveland Pharmland tab. 6, 25 mg in a cell. pack No. 10×3 Release form Tablets 6.25 mg: white or almost white, flat, round, with a chamfer and a risk mark on one side, marbling is allowed. Tablets 12.5 mg: light yellow with light patches, flat, round, with a chamfer and a risk on one side, marbling is allowed. The risk on the tablet is not intended to divide it into equal doses, but serves to make it more convenient to take the drug. The main active ingredient Carvedilol Dosage 6.25 mg Indications for use Essential hypertension (mild to moderate). Chronic angina pectoris for the prevention of attacks. Treatment of stable symptomatic mild, moderate and severe chronic heart failure of ischemic or cardiomyopathic origin in addition to standard therapy (diuretics, digoxin, ACE inhibitors ). Dosage and administration Carveland should be taken with meals, starting with small doses, gradually increasing the dose until the optimal effect is achieved. After the first dose and after each dose change, it is recommended to measure blood pressure in the “standing” position 1 hour after taking the drug, to exclude possible hypotension. Therapy is canceled gradually, reducing the dose within 1-2 weeks. Essential hypertension The recommended starting dose is 12.5 mg once daily for the first 2 days. After 7-14 days of treatment (if necessary – after 2 days) 25 mg once a day. If necessary, the dose can be increased at intervals of no more than 2 weeks, reaching the highest recommended dose of 50 mg 1 time per day (or divided into 2 doses). Chronic angina The recommended starting dose is 12.5 mg twice daily. If necessary, the dose can be increased at intervals of at least 2 weeks, leading up to the highest daily dose of 100 mg, divided into 2 doses. For elderly patients, the highest daily dose is 50 mg divided into 2 doses. Chronic heart failure The dose is selected individually. In patients receiving cardiac glycosides, diuretics and ACE inhibitors, doses should be adjusted before starting treatment with Carveland, the drug is also prescribed for intolerance to ACE inhibitors. The dose of 6.25 mg twice daily is intended for continued treatment of chronic heart failure and not for initiation. With good tolerance, the dose is gradually (with an interval of 2 weeks) increased to the optimal value: then – 12.5 mg twice a day and finally – 25 mg twice a day. The highest tolerated dose is recommended to the patient. The maximum recommended dose is 25 mg 2 times a day. If body weight exceeds 85 kg, then the dose may be increased to 50 mg 2 times a day. If treatment with Karveland is interrupted for more than 2 weeks, then Karveland 6.25 mg tablets should not be taken in the initial period, because they do not provide the 3.125 mg dose necessary for starting. Further, if it is necessary to increase the dose to 6.25 mg and above, Carveland can be used, as previously indicated, the dose should be increased at two-week intervals. Dosage in special groups of patients Impaired renal function. Dose adjustment is not required. Impaired liver function. Carveland is contraindicated in patients with evidence of hepatic impairment. Elderly patients. The initial dose is 12.5 mg 1 time per day. In case of insufficient effectiveness, the dose can be gradually increased at intervals of at least 2 weeks up to a maximum dose of 50 mg per day. Treatment is usually long-term, canceled gradually (within 1-2 weeks), the dose is reduced by half every 3 days. It is necessary to inform the doctor about any change in well-being while taking Karveland (changes in heart rate, blood pressure, body weight)! It may be necessary to adjust the dose of the medications taken. If you take more than the recommended dose of Carveland: If you take more tablets per day than your doctor recommended, or your child has swallowed the tablets, call your doctor or call 911! An overdose is likely to cause a pronounced decrease in blood pressure, heart rate, heart failure; possible cardiac arrest, respiratory failure, vomiting, confusion and convulsions. Stop taking the medicine. As a first aid, it is necessary to lie on your back so that the head is lowered and the legs are raised, rinse the stomach or induce vomiting. Use during pregnancy and lactationCarveland should not be used during pregnancy, in case of emergency, it is used as prescribed by a doctor; contraindicated during lactation, if necessary, breastfeeding should be discontinued. PrecautionsCarveland should not be used in children; with unstable or secondary hypertension; unstable angina; complete interventricular blockade; the final stage of peripheral arterial circulatory disorders; fresh myocardial infarction; tendency to lower blood pressure; concomitant treatment with alpha1 receptor antagonists. Termination of therapy. The drug should be discontinued within 1-2 weeks with limited physical activity. If the condition worsens, consult a doctor. Chronic heart failure. During the period of dose selection, there may be an increase in symptoms of chronic heart failure or fluid retention. It is necessary to consult a doctor. Bronchospasm diseases. If you have chronic bronchitis, emphysema, you should not take the drug. Carveland is used as prescribed by a doctor in cases where the effect of the use of other antihypertensive drugs has not been obtained. If shortness of breath or the first symptoms of bronchospasm appear, you should consult a doctor. Diabetes. If you have diabetes, care should be taken as Carveland may mask or relieve symptoms of hypoglycemia (especially tachycardia). Blood glucose monitoring is recommended, especially when changing the dose or stopping carvedilol. Diseases of the peripheral vessels. If you have peripheral vascular disease (including Raynaud’s syndrome), you should be careful because Carveland may exacerbate the symptoms of arterial insufficiency. thyrotoxicosis. Carveland may reduce the symptoms of thyrotoxicosis. General anesthesia and major surgery. If it is necessary to perform a surgical intervention using general anesthesia, it is necessary to warn the anesthetist about taking Carveland. Bradycardia. Karveland can cause a decrease in heart rate. It is necessary to consult a doctor. Hypotension. The drug can cause a decrease in blood pressure of varying severity. Prescribing low doses at the beginning of treatment, taking the drug during meals and gradually increasing doses reduce the likelihood of this phenomenon. At the initial stage of treatment, driving a vehicle or performing tasks that require increased attention should be avoided. Increased sensitivity. Caution should be exercised when taking Carveland if you have had severe hypersensitivity reactions in the past or are undergoing desensitization. Severe adverse skin reactions. You should not take Carveland if you have had a severe adverse skin reaction in the past. Psoriasis. If you have psoriasis, Carveland should only be used on the advice of a doctor. Simultaneous reception of blockers of “slow” calcium channels. If you are simultaneously taking drugs such as verapamil or diltiazem, as well as other antiarrhythmic drugs, it is recommended to monitor the ECG and blood pressure. Pheochromocytoma. Caution should be exercised when taking Carveland if you have or suspect a pheochromocytoma. Prinzmetal’s angina. It is used with caution due to the possible occurrence of pain. Intraoperative syndrome of atonic iris. If cataract surgery is necessary, inform the doctor about taking the drug to select the operation technique. Contact lenses. Against the background of the reception, a decrease in the amount of lacrimal fluid is possible. Liver damage. Undesirable reactions from a liver are possible, as a rule, reversible. When the first symptoms of liver dysfunction appear (itching, dark urine, loss of appetite, jaundice, pressing pain in the right hypochondrium), you must stop taking the drug and consult a doctor. During the period of treatment, the use of alcohol is excluded. The medicinal product contains lactose and sucrose and should not be used in patients with fructose/galactose intolerance, Lapp lactase deficiency, glucose-galactose/sucrose-isomaltose malabsorption. Interaction with other drugs When prescribing Carveland, be sure to inform your doctor if you are taking any of the following medicines. Perhaps, when they are taken together, a dose adjustment or additional examinations will be necessary: Digoxin – both drugs slow down the conduction of the heart, the concentration of digoxin in the blood increases, more frequent monitoring of the level of digoxin in the blood is recommended. Insulin and hypoglycemic agents taken orally – their ability to lower sugar levels is enhanced, regular monitoring of blood glucose levels is recommended. Rifampicin, cimetidine – affect the concentration of carvedilol in the blood. Drugs that reduce the level of catecholamines (reserpine and MAO inhibitors) – a sharp decrease in blood pressure or heart rate is possible, control of blood pressure and heart rate is recommended. Cyclosporine – it is possible to increase the concentration of cyclosporine, it is necessary to adjust its dose. Verapamil, diltiazem or other antiarrhythmic drugs – increased risk of cardiac conduction disorders. Amiodarone, fluconazole – a decrease in heart rate or cardiac conduction is possible, monitoring of heart rate, ECG is recommended. Quinidine, fluoxetine, paroxetine and propafenone – it is possible to increase the level of carvedilol metabolites in the blood. Clonidine – a decrease in blood pressure and heart rate is possible, control of blood pressure and heart rate is recommended. Verapamil, diltiazem – Conduction disturbances are possible, ECG and blood pressure monitoring is recommended. Antihypertensive drugs – it is possible to potentiate their effect or a sharp decrease in blood pressure, blood pressure control is recommended. Anesthetic drugs – possible decrease in heart rate and blood pressure. Non-steroidal anti-inflammatory drugs (NSAIDs) – the combined use of NSAIDs and beta-blockers can lead to an increase in blood pressure and a decrease in blood pressure control. Beta-adrenergic antagonists – since non-cardioselective beta-blockers interfere with the bronchodilator effect of bronchodilators, which are beta-adrenergic stimulants, careful monitoring of your condition is necessary. Contraindications Do not take carveland If you have: Hypersensitivity to carvedilol or any of the excipients. Chronic heart failure in the stage of decompensation. Chronic obstructive respiratory disease or bronchial asthma. Allergic rhinitis, laryngeal edema. Pulmonary heart. Sick sinus syndrome (including sinoauricular block), atrioventricular (AV) block II and III degree. Severe arterial hypotension (systolic blood pressure < 85 mm Hg). Severe bradycardia (less than 45-50 beats / min at rest). Cardiogenic shock. Myocardial infarction with complications. Clinical manifestation of liver failure. metabolic acidosis. Established belonging to the number of slow metabolizers of debrisoquine and mephenytoin. Fructose or galactose intolerance, Lapp lactase deficiency, glucose-galactose or sucrose-isomaltose malabsorption. Breastfeed. Under 18 years old. Composition Each Karveland tablet contains the active substance carvedilol - 6.25 mg or 12.5 mg and excipients: lactose monohydrate, sucrose, povidone K-30, crospovidone, anhydrous colloidal silicon dioxide, magnesium stearate, iron oxide yellow E 172 (for a dosage of 12.5 mg). Belongs to the group of drugs - adrenoblockers. Expands peripheral vessels and reduces their resistance, which leads to a decrease in blood pressure (BP). Moderately reduces conductivity, strength and heart rate (HR). If you overdosed on a dose of Karveland greater than the doctor recommended: If the number of tablets per day that you have taken exceeds the amount recommended by your doctor, or your child has swallowed the tablets, consult a doctor or call an ambulance! An overdose is likely to cause a pronounced decrease in blood pressure, heart rate, heart failure; possible cardiac arrest, respiratory failure, vomiting, confusion and convulsions. Stop taking the medicine. As a first aid, it is necessary to lie on your back so that the head is lowered and the legs are raised, rinse the stomach or induce vomiting. Side effects Like all medicines, Carveland can cause side effects, although not everybody gets them. Classification of the incidence of side effects according to WHO: very often (? 1/10), often (? 1/100 to 1/<10), infrequently (? 1/1000 to < 1/100), rarely (? 1/10000 to < 1/1000), very rare (< 1/10000), frequency not known (cannot be estimated from available data). Very common: dizziness, headache; progression of heart failure; arterial hypotension; asthenia, fatigue. Often: bronchitis, pneumonia, upper respiratory tract infections, urinary tract infections; anemia; weight gain, increased cholesterol, abnormal blood glucose levels (hyperglycemia, hypoglycemia) in patients with a history of diabetes, hyperuricemia, hyponatremia, increased alkaline phosphatase, glycosuria, hypervolemia, diabetes mellitus, increased GGTP (GGT), weight loss body, hyperkalemia, elevated creatinine; nervousness, depression, depressed mood, decreased concentration, pathological thinking, nightmares, emotional instability; blurred vision, dry eyes, irritation of the mucous membrane of the eyes, blurred vision; tinnitus, hearing loss; bradycardia, edema, hypervolemia, fluid retention; orthostatic hypotension, impaired peripheral circulation (cold extremities, peripheral vascular disease, intermittent claudication, Raynaud's syndrome); dyspnea, pulmonary edema, asthma (in predisposed patients); nausea, diarrhea, vomiting, dyspepsia, abdominal pain, tarry stools, periodontitis; pain in the limbs, cramps; acute renal failure and impaired renal function in patients with widespread peripheral vascular disease and / or impaired renal function, the presence of blood or protein in the urine; frequent urination; pain sensations. Uncommon: sleep disorder, drowsiness; syncope, vertigo, hypesthesia, paresthesia, hypokinesia, dry mouth, increased sweating; atrioventricular blockade, angina pectoris; skin reactions (allergic dermatitis, urticaria, itching, exacerbation of psoriatic rashes, a reaction similar to lichen planus), alopecia; erectile dysfunction. Rarely: a decrease in the number of platelets, prothrombin, purpura; nasal congestion. Very rarely: a decrease in the number of leukocytes; allergic reactions; changes in liver blood tests; involuntary urination in women. If you experience any side effects, talk to your doctor, pharmacist or nurse. This recommendation applies to any possible side effects not even listed in this package insert. Storage conditionsKeep in a place protected from light at a temperature not exceeding 25°C. Keep out of the reach of children. Buy Karveland tablets 6.25 mg No. 10x3 Price for Karveland tablets 6.25 mg No. 10x3