Ascorbic acid with glucose chewable tablets 50mg/438mg №10

NameAscorbic acid with gluc.tablet.zhev.50mg/438mg in kont.b/cell pack No. 10 The main active ingredient Ascorbic acid + dextrose Release form Tablets Dosage 50 mg / 438 mg Indications for use Prevention and treatment of hypo- and avitaminosis C. Conditions of increased need for ascorbic acid: a period of intensive growth, unbalanced nutrition, increased mental and physical stress, a period of convalescence after serious illness, feverish conditions against the background of acute respiratory diseases, acute respiratory viral infections, long-term chronic infections. Dosage and administration Inside after a meal, pre-chew. With a preventive purpose for adults? – 1 tablet (100-200 mg of ascorbic acid) per day. For medicinal purposes: adults 1 – 2? tablets (200 – 500 mg of ascorbic acid) per day, which are divided into 2-5 doses, for children from 14 years old, 1 – 1? tablets (200 – 300 mg of ascorbic acid) per day, which are divided into 2-3 doses. The course of treatment depends on the nature and course of the disease and is determined by the doctor. The maximum daily dose of ascorbic acid for adults is 700 mg. Application during pregnancy and lactation During pregnancy and lactation, they are used only if the intended benefit to the mother outweighs the risk to the fetus and child. Theoretically, there is a danger to the child when the mother uses high doses of ascorbic acid. The minimum daily requirement for ascorbic acid in the II – III trimesters of pregnancy is about 60 mg. The minimum daily requirement during breastfeeding is 80 mg. A mother’s diet containing an adequate amount of ascorbic acid is sufficient to prevent vitamin C deficiency in an infant (it is recommended that the nursing mother not exceed the maximum daily requirement for ascorbic acid). Precautions Simultaneous use of the drug with alkaline drink (mineral water) reduces the absorption of vitamin C. Ascorbic acid can affect the results of various laboratory tests, for example, when determining blood glucose, bilirubin, transaminase activity, lactate dihydrogenase. Patients with high iron content in the body should use ascorbic acid in minimal doses. Appointment of ascorbic acid to patients with rapidly profiling and intensively metastasizing tumors can aggravate the course of the process. In connection with the stimulating effect of ascorbic acid on the synthesis of corticosteroid hormones, it is necessary to monitor kidney function and blood pressure. With prolonged use of large doses, inhibition of the function of the insular apparatus of the pancreas is possible, therefore, in the course of treatment, it must be regularly monitored. Interaction with other drugs Ascorbic acid reduces the toxicity of sulfanilamide drugs, reduces the effect of heparin and indirect anticoagulants, increases the absorption of penicillin, iron, enhances the side effect of salicylates (the risk of crystalluria). The use of oral contraceptives reduces the level of vitamin C in the body. With the simultaneous use of low doses of vitamin C and vitamins B1, B2, and Bc, a mutual enhancement of the therapeutic effect is determined. Vitamin P (rutin) significantly improves the absorption of vitamin C. Simultaneous use of ascorbic acid with therapeutic doses of vitamins B12, PP, B6, with aminophylline, iron and copper preparations should be avoided. Acetylsalicylic acid, oral contraceptives, fresh juices and alkaline drinks reduce the absorption and absorption of ascorbic acid. Ascorbic acid slows down the excretion of acids by the kidneys, increases the excretion of drugs that have an alkaline reaction (including alkaloids), and reduces the concentration of oral contraceptives in the blood. Increases the overall clearance of ethanol, which in turn reduces the concentration of ascorbic acid in the body. When used simultaneously, it reduces the chronotropic effect of isoprenaline. With prolonged use or use in high doses, the interaction of disulfiram-ethanol can be disrupted. In high doses, it increases the excretion of mexiletin by the kidneys. Barbiturates and primidone increase the excretion of ascorbic acid in the urine. Reduces the therapeutic effect of antipsychotic drugs (neuroleptics) – phenothiazine derivatives, tubular reabsorption of amphetamine and tricyclic antidepressants. Contraindications Hypersensitivity to the components of the drug, thrombophlebitis, a tendency to thrombosis, diabetes mellitus. Deficiency of glucose-6-phosphate dehydrogenase, glucose-galactose malabsorption. With caution: Hyperoxaluria, renal failure, hemochromatosis, thalassemia, polycythemia, leukemia, sideroblastic anemia, progressive malignant diseases. Composition Each tablet contains ascorbic acid – 200 mg, glucose monohydrate – 1754 mg; excipients: potato starch, talc, calcium stearate. Overdose Overdose contributes to increased thrombosis. Prolonged, uncontrolled use of the drug can lead to inhibition of the insular apparatus of the pancreas, causing a significant change in metabolism. This must be taken into account when prescribing ascorbic acid to patients with diabetes mellitus. Overdose symptoms: when using more than 1000 mg – headache, increased excitability of the central nervous system, insomnia, nausea, vomiting, diarrhea, hyperacid gastritis, ulceration of the gastrointestinal mucosa, inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria), hyperoxaluria, nephrolithiasis, damage to the glomerular apparatus of the kidneys, moderate pollakiuria (when taking a dose of more than 600 mg / day), a decrease in capillary permeability (possible worsening of tissue trophism, increased blood pressure, hypercoagulability, development of microangiopathies). Side effects If any side effects occur, you should stop taking the drug and consult a doctor. From the side of the central nervous system (CNS): headache, fatigue, with prolonged use of large doses – increased excitability of the central nervous system, sleep disturbances. From the digestive system: irritation of the gastrointestinal mucosa, nausea, vomiting, diarrhea, stomach cramps. From the endocrine system: inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria). From the urinary system: when used in high doses, hyperoxalaturia and the formation of urinary stones and calcium oxalate. From the side of the cardiovascular system: thrombosis, when used in high doses, an increase in blood pressure, the development of microangiopathies, myocardial dystrophy. Allergic reactions: skin rash, rarely – anaphylactic shock. Laboratory indicators: thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia. Others: hypovitaminosis, sensation of heat, with prolonged use of large doses – sodium (Na +) and fluid retention, impaired metabolism of zinc (Zn2 +), copper (Cu2 +). Storage conditions In a place protected from light and moisture at a temperature not exceeding 25 ° C. Keep out of the reach of children. Buy Ascorbic acid with glucose chewable tablets 50mg/438mg №10