Anzibel lozenges for resorption №10х2

Name:
Anzibel paste. d/rassas. in bl. in pack. №10×2
Description:
Almost white round biconvex lozenges, smooth on one side and engraved with the NOBEL logo on the other side. The main active ingredient Chlorhexidine + benzocaine + enoxolone Form of release lozenges Dosage 1 lozenge for resorption contains: chlorhexidine dihydrochloride 5 mg, benzocaine 4 mg, enoxolone 3 mg; excipients: sorbitol, acesulfame potassium, magnesium stearate. Indications for use Local and temporary relief of symptoms of uncomplicated infectious and inflammatory processes in the mouth, stomatitis and sore throat caused by external irritants such as tobacco, sudden changes in temperature, dust that cause pain without fever. Method of administration and doses Method of application: The drug is placed in the oral cavity for slow resorption. Lozenges for lozenges should not be chewed or swallowed whole. Take after eating and brushing your teeth. It is recommended not to rinse your mouth or drink a lot of liquid for 2 hours after using Anzibel. Recommended doses for adults and children over 12 years old: One lozenge for sucking every 2-3 hours. The maximum daily dose is 8 lozenges. The course of treatment should not exceed 7 days. Seek medical attention if symptoms worsen or persist after 2 days of treatment. Recommended dosage for children over 6 years: One lozenge every 4-5 hours. The maximum daily dose is 6 lozenges. Seek medical attention if symptoms worsen or persist after 2 days of treatment. Use during pregnancy and lactation Do not use during pregnancy or lactation. During pregnancy, it should be borne in mind that enoxolone at high doses (> 60 mg / day) and long-term use can lead to sodium retention, edema and hypertension. There are insufficient data on the use of chlorhexidine and benzocaine in pregnant women. In studies of the effect of chlorhexidine on animals, fertility disorders or manifestations of cytotoxic reactions and peri / postpartum toxicity have not been described. It is not known whether chlorhexidine passes into breast milk. There were no violations during pregnancy or lactation with the use of benzocaine. Precautions Do not take Anzibel at higher than recommended doses. Lozenges for resorption should not be chewed or swallowed whole, as the drug acts only locally, being in direct contact with the affected area. It should be borne in mind that the drug contains benzocaine, which can cause a positive doping test result in athletes. Anzibel contains sorbitol, which can cause stomach irritation and diarrhea. The drug should not be taken by patients with hereditary fructose intolerance. Do not take the drug in patients with intolerance to local anesthetics such as esters (especially derivatives of para-aminobenzoic acid), parabens or para-phenylenediamine, as there may be intolerance to benzocaine. The risk-benefit ratio should be assessed in the following cases: severe damage to the oral mucosa (may increase absorption of the anesthetic); fillings and dentures of the anterior teeth (in some cases, staining with chlorhexidine may become permanent). Due to the increased risk of methemoglobinemia, the drug should be used with caution: in patients with difficulty breathing (for example, asthma, bronchitis); in elderly patients; in patients with heart disease. For patients with reduced renal function or patients on a controlled potassium diet, each lozenge contains 0.50 mg of acesulfame potassium. Children: the efficacy and safety of the drug in children under 6 years of age has not been established, so the drug should not be used in patients of this age group. Interaction with other drugs Anzibel should not be used in combination with other drugs containing antiseptics. There are references to studies in animals, which describe that the joint local administration of enoxolone and hydrocortisone potentiates the effect of the latter on the skin. However, these data are not sufficient to determine whether this also leads to an increase in its systemic absorption and toxicity. Due to the presence of benzocaine: Cholinesterase inhibitors: inhibit the metabolism of local anesthetics, there is a risk of systemic toxicity, Sulfonamides: benzocaine metabolites may reduce the antibacterial activity of sulfonamides. Contraindications Anzibel is not used in patients with hypersensitivity to the components of the drug or other local anesthetics – ether derivatives, as well as in patients with phenylketonuria. Composition 1 lozenge for resorption contains: chlorhexidine dihydrochloride 5 mg, benzocaine 4 mg, enoxolone 3 mg Overdose When taking the recommended dose in the instructions, overdose rarely occurs. However, due to the presence of enoxolone, overdose can occur, which can lead to symptoms of hypermineralocorticism, such as sodium retention and potassium loss, edema, hypertension, and inhibition of the renin-angiotensin-aldosterone system. In overdose of chlorhexidine, especially in children, symptoms of alcohol intoxication (slurred speech, numbness or unsteady gait) appear. Although the absorption of benzocaine is very small, however, in the case of systemic absorption, symptoms such as blurred vision and diplopia (double vision), dizziness, convulsions, tinnitus, agitation (CNS stimulation) followed by drowsiness (CNS depression), increased sweating , low blood pressure or bradycardia (slow and irregular heartbeat), depression of the heart. Treatment for overdose with chlorhexidine: symptomatic therapy. Treatment includes oxygen administration or artificial respiration, and intravenous vasoconstrictor fluids are recommended for circulatory depression. With the manifestation of methemoglobinemia (difficulty breathing, dizziness, malaise, weakness), an antidote is used – methylene blue, and gastrointestinal decontamination is also indicated (gastric lavage, ingestion of activated charcoal). Side effects Chlorhexidine may cause temporary staining of the tongue, teeth, dental fillings and dentures. There have been rare cases of irritation of the oral mucosa and the tip of the tongue, which are usually temporary and disappear after discontinuation of the drug. In patients using a solution of chlorhexidine for rinsing the mouth, adverse reactions such as a change in taste sensations and an increase in tartar were often reported, as well as in rare cases, a local allergic reaction was manifested, accompanied by nasal congestion, itching, rash. Adverse reactions that may occur due to the presence of benzocaine are due to overdose or rapid absorption, as well as patient characteristics, and include allergic contact dermatitis and angioedema. Also burning, itching, swelling or redness of the throat, which were not observed before the start of treatment. Enoxolone in high doses and with prolonged treatment can lead to edema and hypertension. It is unlikely that these adverse reactions will occur at the doses used in Anzibel. However, if adverse reactions are observed, it is necessary to stop treatment and consult a doctor. Storage conditionsStore at a temperature not exceeding 25°C. Keep away from children! Buy Anzibel lozenges for resorption No. 10×2 The price of Anzibel lozenges for resorption No. 10×2 Instructions for use for Anzibel lozenges for resorption No. 10×2