Amprilan tablets 5mg №10×3

Name:
Amprilan.
Description:
Amprilan® tablets 5 mg: oval, flat pink tablets with visible inclusions, with bevelled edges, without a shell. The main active ingredient is ramipril. Release form Tablets. Dosage 5 mg. Pharmacological action Amprilan® contains the active substance ramipril. It belongs to a group of drugs called ACE inhibitors (angiotensin converting enzyme inhibitors). The action of Amprilan® is based on: – reducing the body’s production of substances that can increase blood pressure; – relaxation and expansion of blood vessels; – facilitating the work of the heart to move blood through the vessels. Amprilan® is intended for: – treatment of high blood pressure (hypertension); – reduce the risk of myocardial infarction or stroke; – reducing the risk of developing kidney disease (regardless of whether you have diabetes or not); – treatment of heart disease when it cannot move enough blood through the vessels (heart failure); – treatment of conditions after a heart attack (myocardial infarction), complicated by heart failure. Dosage and administration Always take the drug in full accordance with the recommendations of your doctor. Check with your doctor if you are unsure. How to use – Take Amprilan® orally at the same time every day. – Swallow the tablets whole with plenty of liquid. – Do not crush or chew the tablets. Dosage Treatment of High Blood Pressure The usual starting dose is 1.25 mg or 2.5 mg once daily. Your doctor may adjust the dose you are taking until your blood pressure is under control. The maximum daily dose is 10 mg once a day. If you are already taking diuretics (water pills), your doctor may cancel or reduce the amount of diuretic you are taking before starting treatment with Amprilan. Reducing the risk of myocardial infarction or stroke The usual starting dose is 2.5 mg once daily. Your doctor may subsequently increase the dose you are taking. The usual dose is 10 mg once a day. Kidney disease risk warnings You can start at 1.25 mg or 2.5 mg once a day. Your doctor may change the dosage. The usual dose is 5 mg or 10 mg once a day. Treatment of heart failure The usual starting dose is 1.25 mg once daily. Your doctor may change the dosage you are taking. The maximum dose is 10 mg per day. It is preferable to divide the dose into two doses per day. Treatment after myocardial infarction The usual starting dose is 1.25 mg once daily to 2.5 mg twice daily. Your doctor may change the dose you are taking. The usual dose is 10 mg per day. It is preferable to divide the dose into two doses per day. Elderly patients Your doctor will reduce your starting dose and adjust your treatment more slowly. If you have taken more Amprilan® than you should have. If you have taken more than the prescribed dose, seek medical attention immediately. Do not drive! Have someone drive you or call an ambulance. If possible, take the tablets or box with you to show your doctor what you have taken. If you forget to take Amprilan® Do not take a double dose to make up for the missed one. If you forget to take a tablet, take your regular dose when it’s time for your next dose. If you stop taking Amprilan® Continue taking the drug until your doctor asks you to stop treatment. Do not stop taking Amprilan® just because you feel better. The disease may return if treatment is stopped. Use during pregnancy and lactation If you are pregnant or breastfeeding, suspect that you are pregnant or are planning a pregnancy, consult your doctor before taking Amprilan®. Pregnancy You must tell your doctor if you think you are (or might become) pregnant. Your doctor will usually advise you to stop taking Amprilan® before pregnancy or immediately after you find out that you are pregnant, and will advise you to take another drug instead of Amprilan®. Amprilan® is not recommended for early pregnancy, it should not be taken during pregnancy for more than 3 months, as it can cause serious harm to your baby. Breastfeeding Tell your healthcare provider if you are breastfeeding or about to start breastfeeding. Amprilan® is not recommended for the treatment of mothers who are breastfeeding, and your doctor may suggest a different treatment for you if you wish to breastfeed, especially if your baby is a newborn or was born prematurely. Driving vehicles and working with mechanisms You may feel dizzy while taking Amprilan®. This is more likely when you are just starting to take Amprilan® or when you increase the dose. If this happens, refrain from driving and operating machinery. PrecautionsConsult your doctor before taking Amprilan®: – if you have heart, liver or kidney disease; – if you have significant salt or fluid loss (have had vomiting, diarrhea, increased sweating, being on a low-salt diet, long-term use of diuretics (water pills), dialysis treatment); – if you are taking medicines at the same time to reduce allergies to bee or wasp stings (desensitization); – if you are going to take pain medication. This may be necessary for a surgical or dental operation. You may need to stop treatment with Amprilan® the day before. Consult your doctor on this matter; – if you have high levels of potassium in your blood (according to the results of a blood test); – if you are taking drugs or are exposed to conditions that can lower your sodium levels in your blood. Your doctor may order regular blood tests, especially to check your sodium levels in your blood, especially if you are an older person; – if you are taking medicines called mTOR inhibitors (eg temsirolimus, everolimus, sirolimus) or vildagliptin, as these may increase your risk of angioedema, a serious allergic reaction; – if you have a collagenous vascular disease such as scleroderma or systemic lupus erythematosus; – if you are taking any of the following medicines used to treat high blood pressure: angiotensin II receptor blockers (ARB II) (also known as “sartans” – for example, valsartan, telmisartan, irbesartan), especially if you have impaired function kidney associated with diabetes; aliskiren. Your doctor may regularly check your kidney function, blood pressure, and the amount of electrolytes (such as potassium) in your blood. See also the information under the heading “Contraindications”. You must tell your doctor if you think you are (or are planning to become) pregnant. Amprilan® is not recommended for early pregnancy. The drug should not be taken if you are in the second or third trimester of pregnancy, as this can cause serious harm to your baby (see section “Pregnancy and breast-feeding”). Interactions with other drugs Tell your doctor if you are taking, have recently taken or may start taking any other medicines. Amprilan® may affect the effect of some other drugs. Also, some drugs may affect the work of Amprilan®. Please tell your doctor if you are taking any of the following medicines. They can reduce the effect of Amprilan®: – drugs used to relieve pain and inflammation (for example, non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or indomethacin and acetylsalicylic acid), – drugs used for low blood pressure, shock, heart failure , asthma, or allergies such as ephedrine, norepinephrine, or epinephrine. Your doctor will need to check your blood pressure. Please tell your doctor if you are taking any of the following medicines. They may increase the chance of side effects if you take them with Amprilan®: – medicines used to relieve pain and inflammation (for example, non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or indomethacin and acetylsalicylic acid), – medicines to treat cancer (chemotherapy) – temsirolimus (to treat cancer) – drugs to prevent organ rejection after transplantation such as cyclosporine – sirolimus, everolimus (to prevent transplant rejection) diuretics (diuretics) such as furosemide – medicines that can increase the amount of potassium in your blood, such as spironolactone, triamterene, amiloride, potassium salts, and heparin (to thin the blood) – hormonal medicines to treat inflammation, such as prednisone, – allopurinol (used to lower uric acid levels) in the blood), – procainamide (for cardiac arrhythmias), – tr imethoprim and cotrimoxazole (used to treat infections caused by bacteria), vildagliptin (used to treat type 2 diabetes). Please tell your doctor if you are taking any of the following medicines. Amprilan® may affect their effectiveness: – drugs for the treatment of diabetes, such as oral glucose-lowering drugs and insulin. Amprilan® may lower the amount of sugar in the blood. Check your blood sugar while taking Amprilan®. – lithium (for mental illness). Amprilan® may increase the amount of lithium in the blood. The content of lithium in the blood should be carefully monitored by a doctor. If any of the above applies to you (or you are not sure), consult your doctor before taking Amprilan®. Your doctor may need to change your dosage and/or take other precautions: – if you are taking an angiotensin II receptor blocker (ARB II) or aliskiren (see also information under the headings ‘Contraindications’ and ‘Special instructions and precautions’). Amprilan® with food, drink and alcohol – Drinking alcohol together with Amprilan® may cause dizziness or a state of mental disorder. If you are not sure how much alcohol you can drink while taking Amprilan®, discuss this with your doctor, as drugs used to lower blood pressure and alcohol enhance each other’s effects. – Amprilan® can be taken with or without food. Contraindications Do not take this medicine: – if you are allergic to ramipril, any other angiotensin-converting enzyme inhibitors or any of the other ingredients in this medicine (signs of an allergic reaction may include rash, difficulty swallowing or breathing, swelling of the lips, throat or tongue); – if you have ever had a severe allergic reaction called angioedema (symptoms include itching, hives, red spots on the arms, legs and throat, swelling of the throat and tongue, swelling around the eyes and lips, difficulty breathing and swallowing) ; – if you are undergoing dialysis or any other type of blood filtration (depending on the device used, Amprilan® may not be suitable for you); – if you have a kidney disease that reduces the blood supply to the kidney (renal artery stenosis); – if you are in the second or third trimester of pregnancy. It is also better to avoid taking Amprilan® in early pregnancy (see section “Pregnancy and lactation”). – if your blood pressure is too low or unstable. The doctor should assess your condition. – if you have diabetes or impaired kidney function and are being treated with a blood pressure medicine containing aliskiren. Do not take Amprilan® if any of the above apply to you. If you are not sure, consult your doctor before taking Amprilan®. Amprilan® is not recommended for children and adolescents under 18 years of age, since the safety and efficacy of Amprilan® in children has not yet been established. If any of the above applies to you (or you are not sure), consult your doctor before taking Amprilan®. Composition 1 tablet contains 1.25 mg or 2.5 mg or 5 mg or 10 mg of ramipril. Auxiliary ingredients: Sodium bicarbonate, lactose monohydrate, sodium croscarmellose, pregelatinized starch (Starch 1500), sodium stearyl fumarate. The composition of the 2.5 mg tablets additionally includes the PB22886 Yellow pigment mixture (lactose monohydrate, iron oxide yellow (E172)). The composition of the 5 mg tablets additionally includes a pigment mixture PB24899 Pink (lactose monohydrate, iron oxide red (E172), iron oxide yellow (E172)) Stop taking Amprilan® and contact your doctor immediately if you notice any of the following serious side effects. you may need urgent treatment for: – Swelling of the face, lips or throat, difficulty swallowing or breathing, and itching and rash. This may be a sign of a severe allergic reaction to Amprilan®. – Severe skin reactions including rash, mouth ulcers, worsening of pre-existing skin disease, redness, swelling or peeling of the skin (eg Stevens-Johnson syndrome, toxic epidermal necrolysis or erythema multiforme). Tell your doctor right away if you experience: – fast heart rate, irregular or strong heartbeat (palpitations), chest pain, chest tightness, or more serious conditions, including heart attack and stroke. – shortness of breath or cough. These may be signs of lung disease. – bruising, bleeding longer than usual, any signs of bleeding (such as bleeding gums), purple dots and spots on the skin, infections more than usual, sore throat and fever, feeling tired, weak, dizzy or pale skin. These signs can signal diseases of the bone marrow. – Severe pain in the stomach, radiating to the back. This may be a symptom of pancreatitis (inflammation of the pancreas). – fever, chills, tiredness, loss of appetite, stomach pain, nausea, yellowing of the skin or eyes (jaundice). These may be symptoms of liver disease such as hepatitis (inflammation of the liver) or damage to the liver. Other side effects: Please tell your doctor if any of the following symptoms are severe or last longer than a few days. Frequent (may affect up to 1 in 10 people) – headache or feeling tired; – dizziness (the occurrence is more likely at the beginning of treatment with Amprilan® or when the dose is increased); – fainting, an abnormal drop in blood pressure (hypotension), especially if you get up or sit down suddenly; – dry irritating cough, inflammation of the paranasal sinuses (sinusitis) or bronchitis, shortness of breath; – pain in the stomach or intestines, diarrhea, indigestion, nausea or vomiting; – a rash that rises and above the surface of the skin or is smooth; – chest pain; – muscle cramps or pain; – increased levels of potassium in the blood (based on a blood test). Uncommon (may affect up to 1 in 100 people) – imbalance (vertigo); – itching and unusual skin sensitivity, such as numbness, tingling, burning or tingling sensation on the skin (paresthesia); – loss or change in taste sensations; – problems with sleep; – depression, anxiety, nervousness or anxiety; – nasal congestion, difficulty breathing or exacerbation of asthma; – swelling in the intestines called “intestinal angioedema” with symptoms such as abdominal pain, vomiting and diarrhea; – heartburn, constipation or dry mouth; – frequent urination during the day; – increased sweating; – loss or decrease in appetite (anorexia); – fast or irregular heartbeat, swelling of the arms and legs. This may be a sign of fluid retention in the body; – hyperemia; – blurred vision; – joint pain; – fever; – impotence in men, decreased libido in men or women; – an increase in the number of a certain type of white blood cells (eosinophilia), based on a blood test; – changes in the functioning of the liver, pancreas and kidneys, based on the results of laboratory tests. Rare (may affect up to 1 in 1,000 people) – trembling and confusion; – red, swollen tongue; – severe exfoliation or peeling of the skin, itching, pityriasis rash; – changes in the nails (for example, softening or separation of the nail plate from the nail bed); – skin rash or bruising; – spots on the skin and cold extremities; – redness, itching, swelling or watery eyes; – hearing impairment and tinnitus; – feeling of weakness; – a decrease in the number of red blood cells, white blood cells or platelets or hemoglobin levels based on the results of a blood test. Very rare (may affect up to 1 in 10,000 people) – hypersensitivity to sunlight. Frequency unknown (frequency cannot be estimated from the available data) – concentrated urine (dark in color), nausea or vomiting, muscle cramps, confusion and convulsions, which may be caused by abnormal secretion of ADH (antidiuretic hormone). If you have these symptoms, see your doctor as soon as possible. Other side effects: Please tell your doctor if any of the following symptoms become severe or last more than a few days: – difficulty concentrating; – swelling of the mouth; – a blood test shows that there are too few blood cells in the blood; – a blood test shows that there is too little sodium in the blood; – fingers and toes change color in the cold, followed by tingling and soreness in the heat (Raynaud’s phenomenon); – an increase in the mammary glands in men; – slowing down or impaired reactions; – burning sensation; – change in sense of smell; – hair loss. Reporting Adverse Reactions If you experience any adverse reactions, please consult your physician. This recommendation applies to any possible adverse reactions, including those not listed in this package insert. By reporting adverse reactions, you help to get more information about the safety of the drug. Storage conditionsStore at a temperature not exceeding 25°C. Store in the original packaging in a place protected from moisture. Keep out of the reach of children. Buy Amprilan tablets 5mg No. 10×3 Price for Amprilan tablets 5mg No. 10×3