Thioctacid 600BV tablets p/o 600mg №100 №1

Name:
Thioctacid 600 bv.
Description:
One coated tablet contains: Active ingredient: 600 mg of alpha-lipoic acid Excipients: low-substituted hydroxypropyl cellulose, hydroxypropyl cellulose, magnesium stearate, hypromellose (hydroxypropyl methylcellulose), macrogol-6000, talc, titanium dioxide E171, quinoline yellow E104 aluminum hydroxide varnish , indigo carmine (indigotin) E132 aluminum hydroxide varnish. The main active ingredient is thioctic acid. Release form Tablets. Dosage 600 mg. Special instructions Pharmacological group Other drugs used to treat diseases of the digestive tract and metabolic disorders. Thioctic acid ATC code: A16AX01. Pharmacological propertiesThioctic acid (α-lipoic acid) is similar in pharmacological properties to B vitamins. It acts as a coenzyme in the oxidative decarboxylation of α-keto acids. α-Lipoic acid helps to reduce the end products of glycosylation, improve endoneural blood flow, increase the level of glutathione in patients with diabetes mellitus. In preclinical studies of α-lipoic acid, an improvement in trophic processes in neurons has been shown. In clinical studies in patients with diabetic polyneuropathy, the administration of α-lipoic acid led to a decrease in sensory disorders that accompany diabetic polyneuropathy (pain, paresthesia, dysesthesia, numbness). Indications for use Treatment of symptoms of peripheral (sensory-motor) diabetic polyneuropathy. Dosage and Administration Unless otherwise prescribed, take 1 Thioctacid 600 BV film-coated tablet equivalent to 600 mg alpha-lipoic acid once daily as a single dose, approximately 30 minutes before the first meal. Take on an empty stomach, without chewing and drinking plenty of water. Combination with food intake may reduce the absorption of alpha lipoic acid. Therefore, it is recommended to take the entire daily dose half an hour before breakfast, especially in patients with signs of slow digestion. Duration of treatment Since diabetic neuropathy is a chronic disease, it may be necessary to take Thioctacid 600 BV for an extended period of time. The attending physician selects the treatment in each individual case. The basis of the treatment of diabetic polyneuropathy is the optimal treatment of diabetes mellitus. Application during pregnancy and lactation Due to the lack of adequate clinical data, the drug is not recommended for women during pregnancy. There are no data on the penetration of the drug into breast milk. The drug is not recommended for use by women during breastfeeding. Influence on the ability to drive vehicles and other mechanisms In case of signs of adverse reactions from the nervous system (dizziness), it is necessary to refrain from driving vehicles and working with moving mechanisms. PrecautionsAfter the use of Thioctacid 600 BV, a change in the smell of urine is possible, which has no clinical significance. Interaction with other drugs A decrease in the effectiveness of cisplatin was noted when administered simultaneously with Thioctacid 600 BV. Thioctacid 600 BV binds metals. For general reasons, it should not be administered simultaneously with drugs containing metals (for example, iron, magnesium, calcium-containing dairy products). If Thioctacid 600 BV is taken 30 minutes before breakfast, preparations containing iron or magnesium can be taken at lunch or in the evening. The effect of insulin or oral antidiabetic agents in lowering blood sugar levels may be enhanced. Therefore, especially at the beginning of treatment, frequent monitoring of sugar levels is necessary. In some cases, it may be necessary to reduce the dose of insulin and / or oral antidiabetic agents to avoid symptoms of low sugar (hypoglycemia). Caution: Regular alcohol consumption is a significant risk factor for the development and progression of the clinical picture of neuropathy and therefore may adversely affect the process of treatment with Thioctacid 600 BV. Patients with diabetic polyneuropathy are advised to abstain from alcohol. The restriction of alcohol consumption also applies to breaks between courses of treatment. Contraindications Thioctacid 600 BV is absolutely contraindicated in patients with known hypersensitivity to alpha-lipoic acid or any of the excipients. Caution: Thioctacid 600 BV is contraindicated in children and adolescents due to the lack of clinical data on use in this age group. One coated tablet contains: Active ingredient: 600 mg of alpha-lipoic acid Excipients: low-substituted hydroxypropyl cellulose, hydroxypropyl cellulose, magnesium stearate, hypromellose (hydroxypropyl methylcellulose), macrogol-6000, talc, titanium dioxide E171, quinoline yellow E104 aluminum hydroxide varnish , indigo carmine (indigotin) E132 aluminum hydroxide varnish. Overdose In some cases, especially when combined with alcohol, when taking more than 10 g of alpha-lipoic acid, serious, even life-threatening signs of intoxication were observed (such as generalized convulsive seizures, severe acid-base balance disorders leading to lactic acidosis, severe blood clotting disorders) . After taking large doses of alpha-lipoic acid, shock, acute skeletal muscle necrosis, hemolysis, disseminated intravascular coagulation (DIC), bone marrow depression and multiple organ failure can develop. At the slightest concern about possible intoxication with Thioctacid 600 BV (for example, when taking more than 10 tablets of 600 mg for adults or more than 50 mg per kilogram of child weight), immediate hospitalization is indicated with general therapeutic detoxification measures (for example, artificial induction of vomiting, gastric lavage, activated charcoal, etc.), in the treatment of possible consequences and signs, it is necessary to be guided by the principles of modern intensive care and a symptomatic approach. Side effect The frequency of occurrence of adverse reactions is indicated as: very often (≥1 / 10); often (from ≥1/100 to <1/10); infrequently (from ≥1/1000 to <1/100); rarely (from ≥1/10000 to <1/1000); very rarely (<1/10000). From the gastrointestinal tract: often - nausea, very rarely - gastrointestinal disorders such as vomiting, pain in the stomach and intestines, diarrhea. Allergic reactions: very rarely - allergic reactions such as skin rash, urticaria, itching. From the nervous system: often - dizziness; very rarely - a change in taste sensations. Metabolic disorders: very rarely - a decrease in blood sugar levels due to improved glucose uptake. In such cases, symptoms similar to those of hypoglycemia have been described, including dizziness, sweating, headache, and blurred vision. In the event of adverse reactions, including those not listed in the instructions for use, you must stop taking the drug and consult a doctor. Storage conditionsStore at a temperature not exceeding 25 °C. Keep out of the reach of children! Buy Thioctacid 600BV tablets p/o 600mg №100 №1 Price for Thioctacid 600BV tablets p/o 600mg №100 №1