Synthomycin-FT liniment 50mg/g 30g №1

Name:
Synthomycin-FT linim.d/nar.prim.50mg/g in tubes 30g in pack No. 1
Description:
Liniment is white or white with a yellowish tinge of color with a slight specific odor. The main active ingredient DL-chloramphenicol Release form Liniment Dosage 30 g Special instructions and precautions Avoid contact with the eyes of liniment. Uncontrolled treatment with the drug in pediatric practice should not be allowed, it is necessary to use the drug only as directed by a doctor. Antibacterial agents for external use can lead to skin sensitization, and therefore the development of hypersensitivity reactions is possible in the future (when prescribing these drugs externally or in the form of a dosage form with a systemic effect). The composition of the drug includes castor oil, cetostearyl alcohol, sorbic acid, which can cause local skin reactions (for example, contact dermatitis). Liniment is recommended to be used with caution in young children, patients who have previously received cytostatic agents or radiation therapy. Due to the lack of osmotic activity (base – oil, emulsifier), liniment is not recommended for use in the first phase of the wound process (profuse suppuration, pronounced tissue edema, pain and the presence of necrotic tissues). In the course of treatment, regular monitoring of the general blood test is recommended. When applied to large areas of the skin surface at the same time as taking ethanol, a disulfiram-like reaction may develop (skin hyperemia, nausea, vomiting, reflex cough, convulsions). Pharmacological action The mechanism of action of chloramphenicol is due to a violation of protein synthesis in a bacterial cell due to inhibition of peptidyl transferase. Acts bacteriostatically. The drug has a wide spectrum of action: it is active against gram-positive and gram-negative, aerobic and anaerobic microflora: staphylococci, streptococci, Escherichia coli, Pseudomonas aeruginosa, Proteus, clostridia, peptostreptococci, etc., including hospital strains of bacteria with increased resistance to other antibiotics. Drug resistance develops relatively slowly and, as a rule, there is no cross-resistance to other chemotherapeutic agents. Indications for use Local treatment of purulent-inflammatory skin lesions (carbuncles, boils), infected wounds in the II phase of the wound process (absence of pus, necrotic tissues), long-term non-healing trophic ulcers and burns of II-III degree, when the infection is caused by sensitive microorganisms, local treatment of cracks nipples in lactating women. Method of administration and doses It is applied externally. After the primary surgical treatment, the liniment is applied directly to the affected areas of the skin, after which a sterile gauze bandage is applied (or the liniment is applied to the dressing material, and then to the damaged area of the skin). Dressings are carried out depending on the indications every 1-3 days. The duration of treatment is determined individually. With nipple cracks after feeding the child, the mammary gland is carefully washed and 5% liniment is applied on a sterile napkin. The term of application is 2-5 days. Application during pregnancy and lactation Since the pharmacokinetics of synthomycin has not been studied, during periods of pregnancy and breastfeeding, the drug is used with caution and only when, in the opinion of the doctor, the expected benefit to the mother outweighs the potential risk to the fetus. During the treatment of nipple cracks in lactating women, it is not necessary to stop breastfeeding. Before breastfeeding, the remnants of the drug from the nipple and the skin around it should be removed with a clean cloth, and the mammary gland should be thoroughly and gently washed. Interaction with other drugs Simultaneous use of the drug with oleandomycin, nystatin and levorin – increases the antibacterial activity of liniment, and with benzylpenicillin salts and cephalosporins – reduces. The simultaneous use of chloramphenicol with erythromycin and lincosamides is not recommended due to their antagonism. The drug is incompatible with cytostatics, sulfonamides, diphenyl, barbiturates, pyrazolone derivatives, ethanol. Contraindications Individual hypersensitivity to the components of the drug, psoriasis, eczema, fungal skin diseases, hematopoiesis suppression, acute intermittent porphyria, glucose-6-phosphate dehydrogenase deficiency, liver and / or kidney failure, children under 4 weeks of age (neonatal period). Children The drug Synthomycin-FT is contraindicated in children in the first 4 weeks of life (the neonatal period). Composition 1 g of the drug contains 50 mg and 100 mg of DL-chloramphenicol as an active ingredient, respectively. Excipients: unrefined castor oil, cetostearyl alcohol, macrogolglycerol hydroxystearate, sorbic acid, sodium carmellose, purified water. OverdoseSymptoms There may be signs similar to the adverse reactions described in the “Side Effects” section, but to a more pronounced extent. Treatment Treatment is symptomatic. Side effects Like all medicines, this medicine can cause side effects, although not everyone gets them. The frequency is unknown (based on the available data, the frequency of occurrence cannot be determined): allergic reactions (including skin rashes, itching, burning, hyperemia, swelling). Rare – may affect up to 1 in 1,000 people: thrombocytopenia, reticulocytopenia, granulocytopenia, aplastic anemia, erythropenia, agranulocytosis, leukopenia. Reporting Adverse Reactions The patient is advised to consult a physician if they experience any adverse reactions. This recommendation applies to any possible adverse reactions, including those not listed in the instructions for use of the drug. You can also report adverse reactions to the adverse drug reactions (actions) information database, including reports of drug failures. By reporting adverse reactions, you help to get more information about the safety of the drug. Storage conditionsKeep in a place protected from light at a temperature of 8°C to 15°C. Keep out of the reach of children. Buy Synthomycin-FT liniment 50mg/g 30g №1 Price for Synthomycin-FT liniment 50mg/g 30g №1