Stopdiar oral suspension 220mg/5ml 90ml №1

Name:
Stopdiar susp d / vn.prim. 220mg/5ml in 90ml vial with double scoop (for 2.5 ml and 5 ml) in pack No. 1 Main active ingredient Nifuroxazide Release form Suspension Composition 5 ml of suspension contains: active ingredient: 220 mg nifuroxazide; excipients: carbomer, sucrose, citric acid monohydrate (E330), sodium hydroxide (E524), methyl paraben (E218), 30% simethicone emulsion, banana essence, purified water.
Description:
Suspension of light yellow color, with a banana smell; during storage, it settles slightly, but after shaking it returns to a state of homogeneous suspension, leaving no dense sediment at the bottom of the bottle. Dosage 5 ml Pharmacological properties Nifuroxazide is a derivative of 5-nitrofuran. It has an antibacterial effect in the intestinal lumen against certain types of gram-positive bacteria of the genus Staphylococcus and some types of gram-negative bacteria of the Enterobacteriaceae family from the genus Yersinia spp., Escherichia spp., Citrobacter spp., Enterobacter spp., Klebsiella spp., Salmonella spp. Nifuroxazide does not show antibacterial activity against bacteria of the species Proteus vulgaris, Proteus mirabilis and Pseudomonas aeruginosa. Nifuroxazide does not destroy the saprophytic intestinal flora. Does not cause the emergence of strains resistant to nifuroxazide. The exact mechanism of action is not known. Nifuroxazide can inhibit the activity of dehydrogenases and disrupt protein synthesis in bacterial cells. Efficacy does not depend on pH in the intestinal lumen. Nifuroxazide after oral administration is practically not absorbed from the gastrointestinal tract. It is excreted unchanged in the feces. Indications for use – treatment of acute diarrhea of bacterial origin caused by susceptible strains of Staphylococcus spp., Salmonella spp., Escherichia coli in the absence of signs of invasion (for example, deterioration in general condition, fever, toxic infection, etc.). The dose and method of rehydration (oral or intravenous) are determined depending on the severity of diarrhea, age, condition of the patient, the presence of concomitant diseases. Contraindications Nifuroxazide is contraindicated for use in case of hypersensitivity to any of its components, as well as in case of allergy to 5-nitrofuran derivatives. The drug should not be used in premature babies and in children under the age of 2 months. Use during pregnancy and lactation Use of nifuroxazide during pregnancy: There are no clinical data on the use of nifuroxazide during pregnancy. Animal studies do not show any direct or indirect effect on the course of pregnancy, the development of the embryo or fetus, the course of childbirth, or the development of the child after childbirth. Nifuroxazide is preferably not used in pregnant women. Before prescribing the drug, the attending physician should carefully weigh the expected benefits / risks of its use. The use of nifuroxazide during lactation: Nifuroxazide is not absorbed in the gastrointestinal tract. However, due to the lack of sufficient clinical data, caution should be exercised when prescribing nifuroxazide to women who are breastfeeding. Women who are breastfeeding should consult their doctor before taking nifuroxazide. Dosage and administrationSuspension of the drug Stopdiar is used orally. Before use, the vial should be shaken thoroughly until a homogeneous suspension is obtained. If necessary, the suspension can be washed down with water. The drug is taken regardless of the meal. Doses for children: – from 2 to 6 months – 1-2 measuring spoons per 2.5 ml 2 times a day, every 12 hours; – from 7 months to 6 years – 1 measuring spoon per 5 ml 3 times a day, every 8 hours; – adults and children over 7 years old – 1 measuring spoon per 5 ml 4 times a day, every 6 hours. Without consulting a doctor, nifuroxazide should not be taken for more than 3 days. If the symptoms persist after this, a more thorough diagnosis is needed to determine the cause of the symptoms, and antibiotic therapy should also be considered. During the treatment of acute diarrhea, constant oral replenishment of fluid deficiency in the body is mandatory, depending on the general condition of the patient. A 2.5 ml measuring spoon contains 110 mg of nifuroxazide. A 5 ml measuring spoon contains 220 mg of nifuroxazide. Side effect From the side of the hematopoietic and lymphatic system: One case of granulocytopenia is described. From the gastrointestinal tract: In cases of individual hypersensitivity to nifuroxazide, abdominal pain, nausea and exacerbation of diarrhea may occur. In the event of the appearance of such symptoms of low intensity, there is no need for special therapy or discontinuation of the use of nifuroxazide. With the development of the above symptoms of significant intensity, you should stop taking the medication. In the future, the patient should not take nitrofuran derivatives. On the part of the skin and subcutaneous tissue: Rarely, skin reactions appear in the form of a skin rash (from ? 1/10,000 to < 1/1,000). One case of pustulosis in an elderly person and one case of nodular pruritus as a result of contact allergy to nifuroxazide are described. Usually nifuroxazide is well tolerated, practically does not show side effects. In case of any undesirable effects, you should consult your doctor! Overdose One case of an overdose of nifuroxazide oral suspension in a child aged 2 years who took an unspecified amount of the drug has been described. Overdose was manifested by drowsiness and diarrhea, which passed on their own. In case of overdose, gastric lavage and symptomatic treatment are recommended. Interaction with other drugs Alcohol consumption during treatment with nifuroxazide may cause disulfiram-like reactions. While taking nifuroxazide, the simultaneous administration of other oral agents should be avoided due to the strong adsorption properties of the drug. Precautions In case of persistent diarrhea after 3 days of treatment, you should consult your doctor. The physician should determine the cause of the symptoms and consider antibiotic therapy. The drug is used with the obligatory observance of the diet, excluding juices, raw vegetables and fruits, as well as spicy and indigestible foods. During treatment with nifuroxazide, the use of alcoholic beverages is contraindicated, because. the drug increases the body's sensitivity to alcohol and can provoke a reaction expressed by exacerbation of diarrhea, vomiting, abdominal pain, skin flushing, a feeling of heat in the face and upper body, noise in the head, shortness of breath, tachycardia, a feeling of fear. Due to the presence of sucrose in the medicinal product, patients with rare hereditary diseases associated with fructose intolerance, glucose-galactose malabsorption or sucrose-isomaltose deficiency should not take this drug. Storage conditionsStore at temperatures from ±15 °С to ±25 °С Keep out of the reach of children. Buy Stopdiar oral suspension 220mg/5ml 90ml №1