Ruferon-Rn suppositories 250000m №5×2

Name Ruferon-Rn supp. Color heterogeneity in the form of marbling, the presence of a funnel-shaped recess, an air or porous rod is allowed. The main active ingredient Interferon alfa-2b Release form Suppositories Dosage 250,000 IU Special instructions With prolonged use of Ruferon-Rn suppositories, peripheral blood parameters, biochemical markers of liver, kidney, and thyroid function are monitored. Indications for use Ruferon-Rn is used as part of the complex therapy of various infectious and inflammatory diseases in children: SARS, influenza, including those complicated by a bacterial infection, pneumonia (bacterial, viral, chlamydial), sepsis, intrauterine infection. Dosage and administration Ruferon-Rn suppositories are used rectally. In the complex therapy of infectious and inflammatory diseases in infants: 150,000 IU 2 times a day for 5 days. In the complex therapy of viral and bacterial infections: in children 1-7 years old – 250,000 IU 2 times a day for 5 days. Studies have not been conducted in children under 6 months of age. If necessary, courses can be repeated with an interval of 5 days. Use during pregnancy and lactation Not used. The ability to influence the reaction rate when driving vehicles or working with other mechanisms Not used. Precautions In the treatment of primary or recurrent herpes infection, it is not recommended to use the drug Ruferon-Rn, rectal suppositories, in the following cases: – with common, atypical and generalized forms of herpes infection; – in the presence of clinical signs of atopic dermatitis, eczema, seborrheic dermatitis, benign Gougereau-Hailey familial pemphigus; – with skin tumors; – with mental disorders requiring therapy with antidepressants, tranquilizers or hospitalization; – with neutropenia less than 1.5×109/µl; – with thrombopenia less than 90,000/µl; – in diseases associated with impaired function of the immune system. Use in the elderly Not used. Interaction with other drugsRuferon-Rn, rectal suppositories, is compatible and well combined with most drugs used in the treatment of diseases listed in the indications for the use of the drug (antibiotics, glucocorticosteroids, immunosuppressants, etc.). Interferon alpha-2b is able to reduce the activity of P-450 cytochromes and thereby affect the metabolism of cimetidine, phenytoin, chimes, theophylline, diazepam, propranolol, warfarin, and some cytostatics. As a result, the neurotoxic, myelotoxic or cardiotoxic effects of these drugs may be enhanced. Caution should be used simultaneously with narcotic, hypnotic and sedative drugs. Interferons can influence oxidative metabolic processes. This should be taken into account when used simultaneously with drugs metabolized by oxidation (including xanthine derivatives – aminophylline and theophylline). With simultaneous use with theophylline, it is necessary to control the concentration of the latter in the blood serum and, if necessary, adjust the dosing regimen. Contraindications – hypersensitivity to interferon alpha-2b or another component of the drug; – allergic and autoimmune diseases in the acute stage; – severe broncho-obstructive syndrome requiring course use of glucocorticosteroids; – chronic diseases in the stage of decompensation, as well as congenital malformations, metabolic diseases, hereditary diseases; – diseases of the thyroid gland; – severe violations of the function of the kidneys, liver; – severe cardiovascular diseases; – epilepsy and other diseases of the central nervous system; – HIV infection, congenital immunodeficiency; – inhibition of the myeloid germ of hematopoiesis: neutropenia, thrombocytopenia. Composition 1 suppository Ruferon-Rn 250,000 IU contains: active ingredient: human recombinant interferon alpha-2b with an activity of 250,000 IU, excipients: ascorbic acid, glycerol monostearate, solid fat. Overdose Not described. Side effects In rare cases – allergic reactions, namely, skin rashes and itching. These phenomena are reversible and disappear 72 hours after discontinuation of the drug. Storage conditionsKeep in a place protected from light, at a temperature of 2 to 8 °C. Keep out of the reach of children! Buy Ruferon-Rn suppositories 250000me No. 5×2 Price for Ruferon-Rn suppositories 250000me No. 5×2