Iodine alcohol solution for external use 50mg/ml 10ml №1

Name:
Iodine solution alcohol.dnar.approx.50mgml per vial 10ml per pack No. 1
Description:
Transparent red-brown color liquid with a characteristic odor. Composition One vial (10 ml) contains: active ingredient: iodine – 0.5 g, excipients – potassium iodide, ethyl alcohol, purified water. One bottle (800 ml) contains: active substance: iodine – 40 g, excipients – potassium iodide, ethyl alcohol, purified water. One bottle (900 ml) contains: active substance: iodine – 45 g, excipients – potassium iodide, ethyl alcohol, purified water. Pharmacotherapeutic group Antiseptic agent. ATX code: D08AG03. Pharmacological properties Pharmacodynamics Antiseptic agent. The main active ingredient is molecular iodine, which has antimicrobial and antifungal properties. Iodine is able to oxidize and denature the proteins of microorganisms, causing their death. Molecular iodine preparations are characterized by a pronounced local irritating effect on tissues, and in high concentrations – a cauterizing effect. When absorbed and entering the blood, it can have a systemic effect, participating in the synthesis of thyroid hormones. Pharmacokinetics Upon contact with the skin, 30% is converted to iodides, while the rest remains in the form of elemental iodine. Partially absorbed from the skin surface. The absorbed part can enter tissues and organs, being selectively absorbed by the thyroid gland. Iodine is excreted by the kidneys (mainly), intestines, sweat and mammary glands. Absorption of iodine through damaged skin and mucous membranes can be significant. Indications for use It is used externally as an antiseptic for infectious and inflammatory skin diseases, for the treatment of the surgical field, for the prevention of infection of small damage to the integrity of the skin. ContraindicationsIndividual intolerance (including history of hypersensitivity). Patients with impaired thyroid function (hyperthyroidism and adenoma) or receiving lithium therapy. Skin treatment for furunculosis, acne, hemorrhagic diathesis, urticaria, diabetic trophic ulcers is not allowed. Duhring’s dermatitis herpetiformis. Neonatal period. Method of administration and doses When applied externally, a cotton swab is moistened with an iodine solution, which is used to treat the affected areas of the skin. Do not use the drug for more than 10 days. When processing the surgical field, the skin is wiped twice with a sterile gauze swab dipped in a solution of the drug. The total processing time is 4-6 minutes. Side effect Skin irritation, allergic reactions, including angioedema, urticaria, contact dermatitis, with prolonged use on extensive wound surfaces – “iodism” (lacrimation, hypersalivation, rhinorrhea, bronchorrhea, swelling of the mucous membranes). May cause skin hemorrhages or purpura, fever, arthralgia, lymphadenopathy and eosinophilia. Overdose In case of overdose, iodism, irritation and burns are possible. When inhaling concentrated vapors – damage to the upper respiratory tract (burn, laryngo- and bronchospasm); if concentrated solutions get inside – severe burns of the digestive tract; in case of ingestion – the development of hemolysis, hemoglobinuria; the lethal dose is about 3 g. Treatment: gastric lavage with 0.5% sodium thiosulfate solution, intravenous administration of 30% sodium thiosulfate solution – up to 300 ml. In case of a severe skin reaction to iodine, the drug should be removed immediately with 70% ethyl alcohol. It is also recommended to wash the skin with plenty of water for 15 minutes. In case of accidental swallowing, if the patient is conscious – milk inside every 15 minutes. If the drug is not used to treat large open wounds or is used for no more than 10 days, clinically significant systemic absorption is unlikely. Systemic toxicity can lead to shock, tachycardia, fever, metabolic acidosis, and renal failure. Death can be caused by circulatory failure, epiglottis edema leading to asphyxia, aspiration pneumonia, or pulmonary edema. Precautions It is not recommended to use the drug in children under two years of age due to an increased risk of hypothyroidism. The undiluted drug should not be allowed to come into contact with the mucous membranes of the mouth, eyes, vagina and rectum. It is not recommended for use in deep or puncture wounds, severe burns, as the use of the drug may cause excessive absorption of iodine and tissue irritation. Do not use the drug for more than ten days! It is not recommended to treat large areas of the skin with the drug. The use of the drug may affect the results of thyroid function tests. Pregnancy and lactation The use of the drug during pregnancy and lactation is not recommended due to the possible risk of developing thyroid dysfunction in the fetus or child. Children The use of the drug in newborns is contraindicated and the use of the drug in children under two years of age is not recommended due to the high probability of systemic absorption of iodine when applied topically. Topical application in children can lead to severe skin reactions to iodine, iodism, transient hypothyroidism. Interaction with other drugs Pharmaceutical incompatible with essential oils, ammonia solutions, white precipitated mercury (an explosive mixture is formed), with disinfectants containing enzymes. Alkaline or acidic environment, the presence of fat, pus, blood weaken the antiseptic activity. When combined with yellow mercury ointment, the formation of mercury iodide, which has a cauterizing effect, is possible. Upakovka10 ml in a bottle of dark glass. A bottle with a leaflet for use in a pack of cardboard (packaging No. 1). For medical hospitals: 800 ml or 900 ml in a polymer bottle. 6 bottles, together with instructions for use in an amount equal to the number of bottles, in a cardboard box (packaging No. 6). Storage conditions In a place protected from light, at a temperature not exceeding 25 ° C. Keep out of the reach of children. Keep away from fire. Shelf life 2 years. Do not use after the expiry date stated on the package. Conditions for dispensing from pharmacies A bottle of 10 ml (in package No. 1) – without a prescription. Bottles 800 ml or 900 ml – for medical hospitals. Buy Iodine alcohol solution for external use 50mg/ml 10ml No. 1 Price for Iodine alcohol solution for external use 50mg/ml 10ml No. 1