Gilart solution for intra-articular injection in 2 ml pre-filled syringes

Name:
Gilart. Release form Solution. MNN sodium hyaluronate. FTGR Tissue regeneration stimulator.
Description:
Transparent colorless viscous solution. Composition 1 ml contains: Active substance: sodium hyaluronate 15 mg. Excipients: sodium chloride, water for injection. Code ATX M09AX01 Action and pharmacological properties Gilart (sodium hyaluronate) is a polysaccharide consisting of repeating disaccharide units of N-acetylglucosamine and sodium glucuronate, with a molecular weight of up to 2900000 Da. Sodium hyaluronate is produced by bacterial fermentation. Sodium hyaluronate is an important component of connective tissue and is present in high concentrations in the synovial fluid, dermis, vitreous and umbilical cord. In the synovial fluid, sodium hyaluronate acts as a lubricant and shock absorber, ensuring painless movement in the joint. With osteoarthritis, the viscosupplementary properties of the synovial fluid deteriorate significantly, which significantly increases the mechanical load on the joint and leads to the progression of degenerative-dystrophic changes in the cartilage tissue. This is manifested by pain and limited mobility of the joint. The high viscosity and shock-absorbing effect of this drug have an analgesic effect and improve joint mobility when used intra-articularly. Gilart normalizes the mechanical interaction of the elements of the joint and is used as a synovial fluid prosthesis. These effects persist for more than 6 months after a single course of treatment. Indications for useGilart is used to improve the viscosupplementary (visco-elastic) properties of synovial fluid in the treatment of osteoarthritis (osteoarthritis): • gonarthrosis, coxarthrosis, osteoarthrosis of the carpometacarpal and temporomandibular joints; • secondary post-traumatic osteoarthritis of large and medium joints; • osteoarthritis on the background of orthopedic anomalies; Dosage and administration Gilart injections are carried out by medical specialists. Gilart should be injected into the affected joint 3-6 times at weekly intervals. The injected volume depends on the size of the joint, but does not exceed 2 ml for the knee joint and other large joints, or 1 ml for small joints. Several joints can be treated at the same time. Depending on the severity of the joint disease, the effect of the drug can last up to six months or more. A second course of treatment cannot be carried out earlier than 6 months for the same joint. Gilart is intended for intra-articular use only. Do not use intravenously. Gilart is available as a pre-filled syringe, the contents of which do not need to be diluted. The contents of the Gilart pre-filled syringe are sterile and should be used immediately after opening the package. Gilart should be introduced into the joint cavity with careful observance of the administration scheme and the rules of asepsis and antisepsis. The finished syringe is removed from the sterile case, the cap is removed, after which a sterile needle is put on, which is fixed with a slight turn. Before the introduction, you need to remove the air from the syringe. Contraindications • individual intolerance (including history of hypersensitivity) to Gilart’s components; • the presence of infected wounds, abrasions in the joint area; • infectious diseases of the joints; • systemic disorders of blood clotting. Special instructions and precautions It is necessary to follow the scheme of administration and the rules of asepsis and antisepsis for intra-articular administration. Do not use sodium hyaluronate in excess. If pain worsens during insertion, the procedure should be stopped. After the injection of sodium hyaluronate, the patient is advised to adhere to a sparing regimen and avoid excessive stress on the joint for several days. To date, there are no data on the use of the drug in children and adolescents. Gilart should not be used simultaneously with other drugs intended for intra-articular administration. Gilart is for single use only. Reuse is not allowed. The use of opened and/or damaged sterile packaging is not allowed. Re-sterilization is not allowed. The introduction of sodium hyaluronate is carried out at room temperature. Do not use after the expiration date. Side effects Local side effects may occur, such as pain, feeling of warmth, redness, swelling. Storage Store at a temperature not exceeding 25°C in a place protected from light in the original packaging. Do not freeze. Keep out of the reach of children. Shelf life Shelf life: 3 years. Packing 2 ml solution for intra-articular injection 15 mg/ml in pre-filled syringes with a capacity of 2.25 ml. One pre-filled syringe in a coated blister pack. 1 or 3 blister packs with needles in a cardboard box along with a leaflet. Buy Gilart solution for intra-articular injection in pre-filled syringes of 2 ml Price for Gilart solution for intra-articular injection in pre-filled syringes of 2 ml