Framinazin nasal spray 12.5 mg (8000 IU)/1ml 10ml №1

Name:
Framinazin spray 12.5 mg (8000 IU) 1 ml in vial 10 ml in pack No. 1
Description:
Transparent or slightly opalescent, colorless or yellowish solution. The main active ingredient Framycetin Release form spray Dosage 10ml Before using the drug, you should consult with your doctor. After opening the vial and after the first use of the drug, microbial contamination is possible. The vial with the drug should be thrown away after stopping treatment. Pharmacological properties Pharmacodynamics Framycetin sulfate is an antibacterial agent from the group of aminoglycosides for topical use in otolaryngology. The prevalence of acquired resistance of microorganisms to antibacterial agents may vary geographically and over time for individual species of microorganisms. Therefore, it is necessary to have information about the resistance of microorganisms in this region, especially in the treatment of severe infections. The information in this section indicates the probable sensitivity of the bacterial strain to framycetin. Susceptible organisms: gram-positive: Corynebacterium, Listeria monocytogenes, Staphylococcus meti-S; gram-negative: Acinetobacter (especially Acinetobacter baumanii), Branhamella catarrhalis, Campylobacter, Citrobacter freundii, Citrobacier koseri, Enterobacter aerogenes, Enterobacter cloacae, Escherichella coli, Morganophilus influenzae, Haemusus morganii, Proteus mirabilis, Proteus vulgaris, Providencia rettgeri, Salmonella, Serretia, Shigella, Yersinia Moderately susceptible organisms: Gram-negative: Pasteurella Resistant organisms: Gram-positive: Enterococci, Nocardia asteroides, Staphylococcus meti-R*, Streptococcus; Flavobacterium sp, Providencia stuartii, Pseudomonas aeruginosa, Stenotrophomonas maltophilia; anaerobic: certain anaerobic bacteria; others: Chlamydia, Mycoplasma, Rickettsia. ** The level of resistance to methicillin is about 30-50% of all staphylococci in general and is the most common in a hospital setting. Note: This spectrum corresponds to an antibacterial agent in dosage forms intended for systemic use. The concentration created locally with topical application is higher than in the systemic circulation. Data on the kinetics of framycetin when applied topically, local physico-chemical conditions that can affect the activity and stability of the drug in situ, are limited. Pharmacokinetics No pharmacokinetic data available. Indications for use As part of complex therapy for the local treatment of infectious and inflammatory diseases of the nasopharyngeal mucosa. When prescribing this drug, the doctor should be guided by official recommendations regarding the appropriate use of antibacterial drugs. Dosage and administration Adults: one injection in each nostril 4-6 times a day. Children: one injection in each nostril 3 times a day. Duration of treatment – no more than 7 days. The duration of the course of treatment is determined by the doctor, taking into account the characteristics of the disease, the tolerability of the drug and the effect achieved. When using the bottle should be kept in an upright position. Use during pregnancy and lactation is contraindicated during pregnancy and breastfeeding. Interaction with other drugs Clinically significant interactions of the drug with other drugs have not been identified. Contraindications Pregnancy and lactation (breastfeeding); children under 1 year of age; hypersensitivity to framycetin and other antibacterial agents from the aminoglycoside group, as well as auxiliary components of the drug. The drug should not be used to wash the sinuses. Composition 1 ml of the solution contains 12.5 mg (8000 IU) of framycetin sulfate as an active substance. Excipients: glycerin, sodium chloride, sodium citrate, citric acid monohydrate, methyl parahydroxybenzoate, purified water. Overdose Due to the low degree of absorption into the systemic circulation, an overdose is unlikely. Side effects Possible allergic reactions, local irritation of the mucous membrane, toxidermia, angioedema, anaphylactic shock. In the event of adverse reactions, including those not listed in this leaflet, stop using the drug and consult a doctor. Storage conditionsStore in a place protected from light at a temperature not exceeding 25°C. Keep out of the reach of children. Buy Framinazin nasal spray 12.5mg(8000m)/1ml 10ml №1