Efferalgan rectal suppositories 300mg №5×2

Name:
Efferalgan supp. 300mg №10
Description:
Rectal suppositories for children, smooth, glossy, white. The main active ingredient is Paracetamol. Release form Rectal suppositories for children, smooth, glossy, white. Dosage 300 mg No. 10 Special instructions When using the drug for more than 7 days, it is necessary to control the pattern of peripheral blood and the functional state of the liver. Paracetamol distorts the results of laboratory studies of glucose and uric acid in blood plasma. Pharmacological action Analgesic-antipyretic. It has an analgesic and antipyretic effect. Inhibits COX-1 and COX-2 mainly in the central nervous system, affecting the centers of pain and thermoregulation. It has a weak anti-inflammatory effect. Pharmacokinetics Data on the pharmacokinetics of the drug Efferalgan in the form of rectal suppositories are not provided. Indications for use For children aged 3 months to 10 years – acute respiratory infections, influenza, childhood infections, post-vaccination reactions, other infectious and inflammatory diseases and conditions accompanied by fever; – moderate or mild pain syndrome, incl. headache, toothache, muscle pain, neuralgia, pain from injuries and burns. Dosage and administration The drug is used rectally. After releasing the suppository from the package, insert into the child’s anus (preferably after a cleansing enema or spontaneous bowel movement). The average single dose of Efferalgan depends on the body weight of the child and is 10-15 mg / kg 3-4 times / day. The maximum daily dose is 60 mg/kg. Children aged 5 to 10 years (weighing 20 to 30 kg) are administered 1 rectal suppository (300 mg) 3-4 times / day with an interval of 4-6 hours. Do not use more than 4 suppositories per day. Children aged 6 months to 3 years (weighing 10 to 14 kg) are administered 1 rectal suppository (150 mg) 3-4 times / day with an interval of 4-6 hours. Do not use more than 4 suppositories per day. Children aged 3 to 5 months (weighing 6 to 8 kg) are administered 1 rectal suppository (80 mg) 3-4 times / day with an interval of 4-6 hours. Do not use more than 4 suppositories per day. The duration of treatment is 3 days when used as an antipyretic and up to 5 days as an analgesic. Interaction with other drugs With the simultaneous use of Efferalgan with barbiturates, anticonvulsants, rifampicin, the risk of hepatotoxic action is significantly increased. With simultaneous use with levomycetin (chloramphenicol), the toxicity of the latter increases. Paracetamol enhances the effects of indirect anticoagulants. Before testing for uric acid and blood glucose levels, you should inform your doctor about the use of Efferalgan. Contraindications – severe liver dysfunction; – severe renal dysfunction; – blood diseases; – deficiency of glucose-6-phosphate dehydrogenase; – recent inflammation or bleeding in the rectum; – children’s age up to 3 months (for rectal suppositories containing 80 mg of paracetamol); – children’s age up to 6 months (for rectal suppositories containing 150 mg of paracetamol); – children’s age up to 5 years (for rectal suppositories containing 300 mg of paracetamol); – Hypersensitivity to paracetamol. With caution, the drug should be used for violations of the liver or kidneys of mild and moderate degree, with Gilbert’s syndrome. Do not use the drug for diarrhea in a child. Application for violations of liver function With caution, the drug should be used for violations of liver function of mild to moderate degree. Contraindicated in severe liver failure. Application for violations of renal function With caution, the drug should be used for violations of renal function of mild to moderate degree. Contraindicated in severe renal failure. Ingredients paracetamol 300 mg Excipients: semi-synthetic glycerides (up to a suppository weight of 1.3 g). 5 pieces. – blister packs contour (2) – cardboard boxes. Overdose Symptoms: nausea, vomiting, stomach pain, sweating, pallor of the skin. After 1-2 days, signs of liver damage appear. In severe cases, liver failure, hepatonecrosis, encephalopathy and coma develop. Treatment: stop the drug, patients need to consult a doctor. Side effects Allergic reactions: rarely – skin rash, itching, urticaria, Quincke’s edema. From the digestive system: rarely – nausea, vomiting; with prolonged use in high doses, hepatotoxic effects, irritation of the rectal mucosa, tenesmus are possible. On the part of the hematopoietic system: extremely rarely – anemia, thrombocytopenia, leukopenia. Others: with prolonged use in high doses, nephrotoxic effects are possible. The drug is well tolerated at recommended doses. With the development of adverse reactions, it is necessary to stop using the drug and consult a doctor. Storage conditions The drug should be stored out of the reach of children at a temperature not exceeding 30°C. Shelf life – 3 years. Buy Efferalgan rectal suppositories 300mg No. 5×2 Price for Efferalgan rectal suppositories 300mg No. 5×2