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Efferalgan solution for pr. inside 30mg/ml in vial 90ml in pack No. 1
Description:
Syrup (for children) 3% transparent, homogeneous, slightly viscous, yellow-brown in color, with caramel-vanilla taste and smell. The main active ingredient Paracetamol Release form Syrup (for children) 3% transparent, homogeneous, slightly viscous, yellow-brown in color, with a caramel-vanilla taste and smell. 1 ml paracetamol 30 mg Excipients: macrogol 6000, sucrose solution, sodium saccharin, sorbic acid, sodium methyl parahydroxybenzoate, sodium propyl parahydroxybenzoate, caramel-vanilla flavor, water. 90 ml – plastic bottles (1) complete with measuring spoon – cardboard boxes. Dosage 30 mg / ml in 90 ml vial in pack No. 1 Special instructions To avoid exceeding the maximum daily dose, Efferalgan should not be used simultaneously with other drugs containing paracetamol. When using the drug for more than 5-7 days, it is necessary to control the pattern of peripheral blood and the functional state of the liver. Paracetamol distorts the results of laboratory studies of glucose and uric acid in blood plasma. If it is necessary to prescribe the drug to patients with diabetes mellitus or to patients on a low sugar diet, it should be borne in mind that 1 ml of the drug contains 0.335 g of sugar. Persons caring for a sick child should be warned about the need to discontinue the drug and consult a doctor in case of adverse reactions. A doctor’s consultation is also required in the absence of a therapeutic effect: continued fever for more than 3 days and pain for more than 5 days. Pharmacological action Analgesic-antipyretic. It has an analgesic and antipyretic effect. Inhibits COX-1 and COX-2 mainly in the central nervous system, affecting the centers of pain and thermoregulation. In inflamed tissues, cellular peroxidases neutralize the effect of paracetamol on COX, which explains the almost complete absence of its anti-inflammatory effect. It does not adversely affect the water-salt metabolism (sodium and water retention) and the gastrointestinal mucosa due to the lack of influence on the synthesis of prostaglandins in peripheral tissues. The possibility of the formation of methemoglobin is unlikely. Pharmacokinetics Data on the pharmacokinetics of Efferalgan are not available. Indications for use For children aged 3 months to 12 years (weighing 6-32 kg): – fever, incl. with acute respiratory infections, influenza, childhood infections, post-vaccination reactions; – moderate or mild pain syndrome, incl. headache, toothache, muscle pain, neuralgia, pain from injuries and burns. Dosage and administration Inside, both without dilution and after dilution (with water, milk or juice). The average single dose of Efferalgan depends on the body weight of the child and is 10-15 mg / kg 3-4 times a day. The maximum daily dose should not exceed 60 mg/kg. The interval between doses of the drug should be 4-6 hours. Regular time intervals between taking the drug should be followed. For convenience and accuracy of dosing, you must use a measuring spoon. On the measuring spoon, divisions indicating the body weight of the child are applied: 4, 6, 8, 10, 12, 14 or 16 kg. Unmarked divisions correspond to intermediate body weight: 5, 7, 9, 11, 13 or 15 kg. Children weighing between 4 and 16 kg: fill the measuring spoon to the mark corresponding to the child’s body weight, or to the mark closest in value to the child’s body weight. For example, if the weight of the child is from 4 to 5 kg, you should fill the measuring spoon to the mark corresponding to 4 kg. Children weighing 16 to 32 kg: fill the measuring spoon to the mark corresponding to 10 kg, then re-fill so as to get the total body weight of the child. For example, if the weight of the child is from 18 to 19 kg, you should fill the measuring spoon to the mark corresponding to 10 kg, then again to the mark of 8 kg. The duration of treatment is 3 days as an antipyretic and up to 5 days as an analgesic. If you need to continue taking the drug, you need to consult a doctor. Precautions The use of the drug is contraindicated in severe liver dysfunction. With caution, the drug should be used for mild to moderate liver dysfunction, with Gilbert’s syndrome. The use of the drug is contraindicated in severe violations of kidney function. With caution, the drug should be used for mild to moderate renal impairment. The use of the drug in children under the age of 1 month is contraindicated. Interaction with other drugs With the simultaneous use of Efferalgan with barbiturates, tricyclic antidepressants, anticonvulsants (phenytoin), zixorine, phenylbutazone, rifampicin, ethanol, the risk of developing a hepatotoxic effect is significantly increased. When taken together with salicylates, the risk of nephrotoxicity increases significantly. With simultaneous use with levomycetin (chloramphenicol), the toxicity of the latter increases. Paracetamol enhances the effect of indirect anticoagulants. Paracetamol reduces the effectiveness of uricosuric drugs. Contraindications – severe liver dysfunction; – severe renal dysfunction; – blood diseases; – deficiency of glucose-6-phosphate dehydrogenase; – children’s age up to 1 month; – hypersensitivity to the components of the drug, especially parabens (methyl and propyl parahydroxybenzoate). With caution, the drug should be used for violations of the liver or kidneys of mild and moderate degree, with Gilbert’s syndrome. Composition 1 ml paracetamol 30 mg Excipients: macrogol 6000, sucrose solution, sodium saccharin, sorbic acid, sodium methyl parahydroxybenzoate, sodium propyl parahydroxybenzoate, caramel-vanilla flavor, water. 90 ml – plastic bottles (1) complete with measuring spoon – cardboard boxes. Overdose Symptoms: nausea, vomiting, stomach pain, sweating, pallor of the skin. After 1-2 days, signs of liver damage appear – pain in the liver, increased activity of hepatic transaminases in the blood, an increase in prothrombin time. In severe cases, liver failure, hepatonecrosis, encephalopathy and coma develop. Treatment: stop the drug, it is recommended gastric lavage, taking enterosorbents (activated carbon, polyphepan), intravenous administration of N-acetylcysteine antidote, taking methionine, clinical monitoring of the patient’s condition. Side effects Allergic reactions: possible – skin rash, itching, Quincke’s edema. From the digestive system: possible – nausea, vomiting, abdominal pain; with prolonged use in high doses, a hepatotoxic effect is possible. From the hemopoietic system: rarely – anemia, leukopenia, agranulocytosis, thrombocytopenia; with prolonged use in high doses, the development of methemoglobinemia and pancytopenia is possible. Others: with prolonged use in high doses, nephrotoxic effects are possible. Storage conditions The drug should be stored out of the reach of children, in a dry place at a temperature not exceeding 30°C. Buy Efferalgan oral solution 30mg/ml 90ml №1 Price for Efferalgan oral solution 30mg/ml 90ml №1
Efferalgan oral solution 30mg/ml 90ml №1
$24.00
INN | PARACETAMOL |
---|---|
The code | 4 494 |
Barcode | 3 585 553 246 954 |
Dosage | 30mg/ml |
Active substance | Paracetamol |
Manufacturer | UPSA SAS, France |
Importer | "VitPharmMarket" LLC Vitebsk, Republic of Belarus, 210004 Vitebsk, 5th Kooperativnaya st., 8; ALC "Dominantafarm", Minsk, 220140 Minsk, Dombrovskaya st., 15, room 10a, room 10a-41; Closed joint-stock company "Unipharm", 223060, Minsk region, Novodvorsky s / council, 40-1, room. 36, area of the village of Bolshoye Stiklevo; Foreign unitary trade and manufacturing enterprise "Belinvestfarma", Minsk, Leshchinskogo st., 8/4-2; ODO "TISHAS", Minsk, 220028 Belarus, Minsk, Mayakovsky st., 144, room 7; LLC "LIGMATON", Republic of Belarus, Minsk region, Minsk district, Senitsky s / s, 68/3-3, Senitsa district., 223056; SOOO "Brititrade", 223021, Minsk district, Shchomyslitsky s / s, 18 |
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