NameAmizon tablets p/o 0.25g in blister pack No. 10×1 Minor inclusions are allowed on the surface of the core tablets. The main active ingredient is amizon Release form of the tablet Dosage 1 tablet contains amizon® (enisamium iodide) 125 mg (0.125 g) or 250 mg (0.25 g); PharmacodynamicsAmizon® is an isonicotinic acid derivative with antiviral activity. In animal experiments, it suppresses the action of influenza viruses and other pathogens of acute respiratory viral infections due to a direct inhibitory effect on the process of penetration of viruses through the cell membrane. It has interferonogenic properties, increases the concentration of endogenous interferon (interferon alpha and interferon gamma) in blood plasma. Increases the body’s resistance to viral infections. Reduces acute clinical manifestations of viral intoxication, helps to reduce the duration of the disease. PharmacokineticsAfter oral administration, Amizon quickly enters the bloodstream, its maximum concentration in the blood is observed 2-2.5 hours after administration. The half-life is 13.5-14 hours, it is metabolized in the liver, but is rapidly excreted from the tissues (the half-life is 2-3 hours). It is excreted from the body by 90-95% with urine in the form of metabolites. Indications for use Treatment and prevention of diseases: influenza and other acute respiratory viral infections in adults and children over 6 years of age. Dosage and administrationAmizon® is administered orally after meals, without chewing. The maximum single dose is 1000 mg, the daily dose is 2000 mg. The recommended course of treatment, depending on the severity and etiology of the disease, is from 5 to 30 days. Influenza and other respiratory viral infections Treatment. Adults and children over 12 years of age are prescribed 250-500 mg 2-4 times a day for 5-7 days; children from 6 to 12 years old are prescribed 125 mg 2-3 times a day for 5-7 days. Prevention. Adults and children over 16 years old – 250 mg per day for 3-5 days, then – 250 mg 1 time in 2-3 days for 2-3 weeks; children 6-12 years old – 125 mg every other day for 2-3 weeks; children from 12 to 16 years old – 250 mg every other day for 2-3 weeks. Use during pregnancy and lactation The drug is contraindicated for use in the first trimester of pregnancy. Use in the II and III trimester of pregnancy is possible only on prescription. Data on the use of women who are breastfeeding are not available. Precautions It is necessary to prescribe the drug with caution in patients with thyroid diseases, especially with hyperthyroidism. The drug contains lactose, so patients with rare hereditary forms of galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome should not use the drug. Use during pregnancy or lactation. The drug is contraindicated for use in the first trimester of pregnancy. Use in the II and III trimester of pregnancy is possible only on prescription. Data on the use of women who are breastfeeding are not available. Children. The drug in this dosage form is not used to treat children under 6 years of age. The ability to influence the reaction rate when driving vehicles or working with other mechanisms. Taking the drug Amizon® does not affect the ability to drive vehicles or work with other mechanisms. Interaction with other drugsAmizon® enhances the effect of antibacterial and immunomodulatory agents. It is advisable to combine this drug with ascorbic acid and other vitamins. Amizon® can also be administered simultaneously with the use of recombinant interferon. Contraindications – Hypersensitivity to any of the components of the drug; – Lactase deficiency, lactose intolerance, glucose-galactose malabsorption; – Pregnancy; – lactation period; – Severe organic lesions of the liver and kidneys. – Children’s age (up to 6 years). Active ingredient: Amizon® (enisamium iodide); 1 tablet contains Amizon® (enisamium iodide) 125 mg (0.125 g) or 250 mg (0.25 g); excipients: lactose monohydrate, microcrystalline cellulose, povidone, croscarmellose sodium, calcium stearate; sheath: OPADRY II Clear 85F19250 (polyvinyl alcohol, talc, polyethylene glycol, polysorbate 80). Overdose No cases of overdose with Amizon have been reported. In case of an overdose, it is possible to increase the manifestations of adverse reactions: staining of the mucous membranes in brown, vomiting, abdominal pain and diarrhea. The development of edema, erythema, acne-like and bullous rashes, and fever may occur. Treatment: gastric lavage, symptomatic treatment. Side effects Allergic reactions: hypersensitivity reactions, including skin rashes, urticaria, angioedema, itching. From the digestive system: dryness and bitter taste in the mouth, swelling of the oral mucosa, hypersalivation, yellow staining of the tongue, nausea, vomiting, heartburn, abdominal pain, heaviness in the right hypochondrium, diarrhea, bloating. From the respiratory system: shortness of breath, irritation of the throat. In the post-registration period, in isolated cases, the following adverse reactions were noted: headache, dizziness, weakness, fluctuations in blood pressure. Storage conditions Store in a place protected from light at a temperature not exceeding 25 ° C. Keep out of the reach of children. Buy Amizon tablets p/o 0.25g No. 10×1 Price for Amizon tablets p/o 0.25g No. 10×1
The code | 17220 |
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Barcode | 4 823 002 214 338 |
Dosage | 0.25g |
Active substance | Amizon |
Manufacturer | Farmak PAO, Ukraine |
Importer | IOOO Interfarmaks 223028 Minsk region, Minsk district, Zhdanovichsky s / s, ag. Zhdanovichi, st. Star, 19a-5, room. 5-2 |
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