Title: Phosphatelyte: 120 Capsules (480mg) for Phosphate Kidney Stones

Product Description:

Phosphatelyte is a comprehensive dietary supplement formulated to support kidney health and specifically address the formation of phosphate kidney stones. This powerful blend of carefully selected ingredients works synergistically to promote urinary tract health and reduce the risk of stone recurrence.

Key Ingredients and Their Benefits:

• Bergenia Extract (Bergenia ligulata): This extract has been shown to significantly reduce the growth rate of calcium phosphate crystals in urine. Studies indicate it also increases urinary magnesium excretion, a key mineral for preventing stone formation, and possesses anti-inflammatory properties to protect kidney cells. Furthermore, its diuretic effect aids in flushing out urinary waste. [1, 2, 3, 4, 5]
• Calcium Carbonate: A naturally occurring mineral, calcium carbonate is clinically proven to lower blood phosphorus and phosphate levels, particularly beneficial for individuals with chronic kidney disease. Studies demonstrate a significant reduction in phosphate levels after 2 and 24 months of consistent use. [6, 7]
• Nicotinamide (Vitamin B3): This essential B vitamin plays a crucial role in multiple metabolic processes. Research indicates nicotinamide effectively reduces blood phosphate levels by inhibiting phosphate transport in the kidneys and intestines. Its effectiveness, excellent tolerability, and cost-effectiveness make it a valuable component in managing elevated phosphate levels. [8, 9, 10]
• Cranberry Extract (Vaccinium macrocarpon Ait.): Long used in urological practices, cranberry extract helps increase urinary acidity (lowering pH), creating an environment less conducive to phosphate stone formation. It also reduces urinary uric acid levels and offers additional antimicrobial and antioxidant benefits to support overall urinary tract health. [11, 12, 13]

Scientific References:

1. Joshi VS, et al. Journal of Crystal Growth, Feb. 2005, vol. 275, no. 1–2,
2. Joshi VS, et al. Urol Res. 2005 May; 33(2):80-6.
3. Tiselius HG, et al. BJU Int. 2003 May; 91(8):758-67.
4. Singh A, et al. J. Ethnopharmacol. 2021 Jul; 275:114104.
5. Singh N, et al. J. Pharm. Res. 2009; 2:958–960
6. Miller D, et al. ASAIO Trans. 1989 Jul-Sep; 35(3):322-4.
7. Malberti et al. Am J Kidney Dis. 1988; 12(6):487-91.
8. Restrepo Valencia CA, et al. Nefrologia. 2008; 28(1):61-69.
9. Rennick A, et al. Pharmacotherapy. 2013; 33(6):683–690.
10. Lenglet A, et al. Drugs R D. 2013; 13(3):165–73.
11. Raz R. Clin Infect Dis. 2004 May 15; 38(10):1413-9.
12. Gettman MT. J Urol. 2005; 174(2):590-4.
13. Ledda A, et al. Eur Rev Med Pharmacol Sci. 2015; 19(Suppl 1):77-80.

Contraindications:

Individual intolerance to any component, pregnancy, and breastfeeding.

Instructions:

Consult your doctor before use. Adults should take 1 capsule twice daily with meals for one month. The course can be repeated if necessary.

Storage:

Store in a cool, dry place, out of reach of children, below 25°C.

Shelf Life:

2 years.

Keywords:

Phosphate kidney stones, kidney stones, Phosphatelyte, kidney health, urinary tract health, Bergenia extract, calcium carbonate, nicotinamide, vitamin B3, cranberry extract, urinary tract infection, UTI, kidney stone prevention, kidney stone treatment, supplement, dietary supplement, calcium phosphate crystals, magnesium, uric acid, diuretic, anti-inflammatory.