Moxifloxacin Eye Drops 5mg/ml: Effective Treatment for Bacterial Eye Infections
This comprehensive guide provides detailed information about Moxifloxacin eye drops, a powerful antibiotic used to treat bacterial infections of the eye.
Product Details:
- Name: Moxifloxacin eye drops 5mg/ml
- Packaging: 5ml bottle, pack of 1
- Active ingredient: Moxifloxacin hydrochloride monohydrate 5.45 mg (equivalent to 5.00 mg moxifloxacin)
- Excipients: Sodium chloride, Boric acid, Sodium hydroxide, Purified water
Description:
Moxifloxacin eye drops are a clear, greenish-yellow solution. This potent antibiotic belongs to the fluoroquinolone family and is effective against a wide range of bacteria commonly responsible for eye infections.
How it Works:
Moxifloxacin works by inhibiting the activity of DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication, repair, and recombination. This action effectively stops the growth and multiplication of bacteria, allowing the body to fight off the infection.
Usage:
- For topical use in the eye only.
- Not for injection.
- Do not administer under the conjunctiva or directly into the anterior chamber of the eye.
Dosage:
- Adults (including the elderly): 1 drop in the affected eye(s) three times a day.
- Improvement: Typically observed within 5 days. Continue treatment for an additional 2-3 days.
- No improvement after 5 days: Consult your doctor for diagnosis and/or treatment reevaluation.
- Duration: Depends on the severity of the infection, clinical presentation, and bacteriological response.
- Children: No dosage adjustment necessary.
- Patients with liver and kidney impairment: No dosage adjustment necessary.
Administration:
- Wash hands thoroughly before instillation.
- Tilt your head back.
- Pull down the lower eyelid and look up.
- Drop 1 drop into the space between the eyelid and the eyeball by pressing on the bottom of the vial.
- Avoid touching the tip of the bottle to the eyelids, eyelashes, or hands.
- Close your eye and blot excess drops with a dry cotton swab.
- Lightly press the inner corner of your eye for 3-5 minutes without opening it. This enhances the effectiveness of the drops.
Precautions:
- To prevent microbial contamination of the dropper and solution: Avoid touching the dropper to eyelids, surrounding areas, or other surfaces.
- To prevent absorption through the nasal mucosa: Close the lacrimal-nasal canals for 2-3 minutes after application, especially in newborns and children.
- When using multiple ophthalmic medications: Maintain a minimum 5-minute interval between applications. Apply eye ointments last.
Contraindications:
- Hypersensitivity to moxifloxacin, other quinolones, or any of the excipients listed in the Composition section.
Side Effects:
- Most common: Eye irritation and eye pain (1-2% of cases).
- Severity: Mild in 96% of patients experiencing side effects, treatment discontinued in only 1 patient.
Adverse Reactions (by system organ class and frequency):
- Very often (≥1/10): None reported.
- Often (≥1/100 – <1/10): Taste disorders.
- Infrequently (≥1/1,000 – <1/100): Headache, vomiting, increased ALT and GGT levels.
- Rarely (≥1/10,000 – <1/1,000): Decreased hemoglobin, paresthesia, nasal/pharyngo-laryngeal pain, dyspnea, corneal epithelial injury, corneal injury, conjunctivitis, blepharitis, eye edema, conjunctival edema, blurred vision, decreased visual acuity, asthenopia, eyelid erythema.
- Very rare (<1/10,000): Palpitations, redness, rash, itching, urticaria.
- Frequency not known: Hypersensitivity reactions, bleeding, eye flushing, eye itching, eyelid edema, eye discomfort, endophthalmitis, ulcerative keratitis, corneal erosion, corneal thinning, increased intraocular pressure, corneal clouding, corneal infiltrate, corneal deposits, eye allergy, keratitis, corneal edema, photophobia, increased lacrimation, secretion from the eyes, foreign body sensation in the eye, foreign body sensation in the throat, nausea.
Always consult your healthcare professional before using Moxifloxacin eye drops or any other medication. This information is for educational purposes only and should not be considered medical advice.
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