Metformin LONG 500 Tablets: Control Type 2 Diabetes with Extended Release
Description:
Metformin LONG 500 tablets are a long-acting, extended-release formulation of metformin hydrochloride, a medication used to manage type 2 diabetes in adults. This comprehensive guide provides detailed information on its uses, dosage, potential side effects, and essential safety precautions.
How Metformin LONG 500 Works:
Metformin is a biguanide, a class of drugs that work by reducing both basal and postprandial blood glucose levels. It achieves this without stimulating insulin secretion, making it a safe option for patients without hypoglycemia risk. Metformin enhances the sensitivity of peripheral receptors to insulin, promoting efficient glucose utilization by cells. Additionally, it reduces glucose production by the liver and delays glucose absorption from the intestines.
Key Benefits of Metformin LONG 500:
- Extended Release for Consistent Blood Sugar Control: The long-acting formula helps maintain stable blood sugar levels throughout the day, reducing the need for frequent dosage adjustments.
- Low Hypoglycemia Risk: Unlike insulin and certain other diabetes medications, Metformin does not cause low blood sugar (hypoglycemia) when used alone.
- Potential for Weight Management: Metformin can promote weight loss by improving insulin sensitivity and reducing glucose production.
Dosage and Administration:
The recommended starting dose is one tablet of Metformin LONG 500 per day, taken once a day with meals, typically in the evening. Dosage can be gradually increased every 10-15 days, based on blood glucose monitoring results. The maximum recommended dose is 4 tablets per day (2000 mg).
Important Safety Information:
- Renal Function: Metformin is excreted by the kidneys, so it’s crucial to have regular kidney function assessments before starting treatment and throughout.
- Lactic Acidosis: A rare but serious complication, lactic acidosis, can occur with metformin use, particularly in patients with compromised renal function. Consult your doctor immediately if you experience symptoms such as muscle cramps, fatigue, abdominal pain, or rapid breathing.
- Alcohol Consumption: Avoid alcohol intake while taking Metformin LONG 500, as it can increase the risk of lactic acidosis.
- Pregnancy and Breastfeeding: Metformin is not recommended for use during pregnancy or breastfeeding.
Potential Side Effects:
The most common side effects are gastrointestinal, such as nausea, vomiting, diarrhea, and abdominal pain. These side effects are more frequent at the start of treatment and often resolve on their own. To minimize these, it’s advisable to take metformin with meals and gradually increase the dosage.
Interactions with Other Medications:
Metformin can interact with various medications, including:
- Iodine-containing contrast agents
- Alcohol
- Danazol
- Chlorpromazine
- Glucocorticosteroids
- Diuretics
- Beta-2 sympathomimetics
- Angiotensin-converting enzyme (ACE) inhibitors
- Drugs affecting organic cation transporters (OCTs)
- Sulfonylurea derivatives
- Insulin
- Acarbose
- Salicylates
- Nifedipine
It is crucial to inform your doctor about all medications and supplements you’re taking, both prescription and over-the-counter.
Before Starting Metformin LONG 500:
Consult your doctor if you have any of the following:
- Pre-existing kidney or liver problems
- History of lactic acidosis
- Heart failure
- Upcoming surgery
- Plan to undergo a radiological examination with iodine-containing contrast agents
Always consult your healthcare professional for personalized advice on managing type 2 diabetes and using Metformin LONG 500. This information should not be considered medical advice and does not substitute professional medical guidance.
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