L-Thyroxin 150 Berlin-Chemie tabl 150mcg in bl. in pack. №25×4

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L-Thyroxine 150 Berlin-Chemie: A Comprehensive Guide to Thyroid Hormone Replacement Therapy

Find the information you need about L-Thyroxine 150 Berlin-Chemie, a medication used to treat hypothyroidism, goiter, and thyroid cancer. This comprehensive guide covers everything from the medication’s uses and benefits to potential side effects and interactions with other medications.

What is L-Thyroxine 150 Berlin-Chemie?

L-Thyroxine 150 Berlin-Chemie is a medication containing the active ingredient levothyroxine sodium, a synthetic form of the thyroid hormone thyroxine. It is used to replace missing thyroid hormone in individuals with hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone.

L-Thyroxine 150 Berlin-Chemie is used for:

• Hypothyroidism: This includes all forms of hypothyroidism, a condition where the body doesn’t produce enough thyroid hormone.
• Prevention of goiter recurrence: This applies after surgery to remove a goiter (enlarged thyroid gland) in individuals with normal thyroid function.
• Treatment of benign goiter: This is used for goiters with normal thyroid function.
• Treatment of thyroid cancer: It helps suppress the recurrence of thyroid cancer, mainly after surgery, and replaces the missing thyroid hormone.
• Thyroid function studies: It’s used in a thyroid suppression test to assess thyroid function.

L-Thyroxine 150 Berlin-Chemie is used in all age groups, including children.

Important Information:

L-Thyroxine 150 Berlin-Chemie is contraindicated in the following situations:

• Allergy: If you have an allergy to levothyroxine sodium or any other component of the medication.
• Untreated hyperthyroidism: If you have an overactive thyroid gland.
• Untreated adrenal insufficiency: If you have insufficient production of hormones by the adrenal glands.
• Untreated pituitary insufficiency: If you have insufficient production of hormones by the pituitary gland, especially if it has led to adrenal insufficiency that requires treatment.
• Recent acute myocardial infarction: If you have recently had a heart attack.
• Acute inflammation of the heart muscle: If you have acute myocarditis or pancarditis (inflammation of all layers of the heart wall).
• Pregnancy and concomitant use of hyperthyroid medications: If you are pregnant and taking medications for hyperthyroidism (thyreostatics).

Before taking L-Thyroxine 150 Berlin-Chemie:

• Conditions to be excluded or treated: Ensure you have treated or ruled out conditions like coronary artery disease, angina pectoris, high blood pressure, pituitary and/or adrenal insufficiency, and thyroid autonomy.

Warnings and Precautions:

• Heart conditions: If you have a history of heart attack, coronary artery disease, heart failure, or long-term hypothyroidism, monitor your thyroid hormone levels closely.
• Pituitary disease: If hypothyroidism is caused by a pituitary gland problem, treat any accompanying adrenal insufficiency before starting treatment with thyroid hormone.
• Thyroid autonomy: If you suspect thyroid autonomy (areas in the thyroid gland that produce uncontrolled thyroid hormone), consult your doctor for a thyroid function test before starting treatment.
• Postmenopausal women: Monitor thyroid function more frequently in postmenopausal women with an increased risk of osteoporosis.
• Diabetes and anticoagulants: Consult your doctor if you have diabetes or take certain anticoagulants (e.g., dicoumarol).
• Mental disorders: Contact your doctor immediately if you experience mental disorder symptoms as dosage adjustment may be necessary.
• Dialysis patients: If you are on dialysis and taking Sevelamer for elevated blood phosphate levels, your doctor may monitor certain blood parameters.
• Orlistat: If you are taking orlistat (an anti-obesity drug), either stop taking it or consult your doctor for a dose adjustment.
• Soy products: If you consume soy products, your doctor should monitor your thyroid hormone levels more frequently.
• Misuse: Do not take L-Thyroxine 150 Berlin-Chemie for weight loss. It will not help you lose weight if you have normal thyroid hormone levels.
• Changing therapy: Do not switch from L-Thyroxine 150 Berlin-Chemie to another thyroid hormone medication without consulting your doctor and monitoring blood parameters.

Elderly patients: Elderly patients need careful dosage (especially those with heart disease) and more frequent medical supervision.

Interactions with other medications:

• Antidiabetic drugs: Monitor your blood sugar levels regularly, especially at the beginning of thyroid hormone treatment.
• Coumarin derivatives (anticoagulants): Monitor your blood coagulation parameters regularly.
• Blood lipid-lowering and potassium-lowering medications: Take these medications 4-5 hours after taking L-Thyroxine 150 Berlin-Chemie.
• Sevelamer and lanthanum carbonate: Your doctor may monitor certain blood parameters.
• Aluminum-containing antacids, iron and calcium-containing drugs: Take these medications at least 2 hours after taking L-Thyroxine 150 Berlin-Chemie.
• Propylthiouracil, glucocorticoids, beta-blockers: These medications may reduce the effectiveness of L-Thyroxine 150 Berlin-Chemie.
• Amiodarone, iodinated radiopaque agents: Your doctor may adjust the dose of L-Thyroxine 150 Berlin-Chemie.
• Contraceptives or hormone replacement therapy: Your need for levothyroxine may increase.
• Sertraline, chloroquine/proguanil: These medications reduce the effectiveness of levothyroxine.
• Barbiturates, rifampicin, carbamazepine: These medications may reduce the effect of levothyroxine.
• Protease inhibitors, phenytoin: Your doctor should monitor your symptoms and thyroid function.
• Tyrosine kinase inhibitors: You may need a higher dose of levothyroxine.
• Orlistat: Orlistat may reduce the effectiveness of levothyroxine.

Taking L-Thyroxine 150 Berlin-Chemie with food and drink:

• Avoid calcium-rich foods: Do not take the medication with foods high in calcium, milk, or dairy products.
• Empty stomach: Take the medication in the morning on an empty stomach at least half an hour before breakfast.

Pregnancy, breastfeeding, and fertility:

• Consult your doctor: Talk to your doctor before taking L-Thyroxine 150 Berlin-Chemie if you are pregnant, breastfeeding, or planning to become pregnant.
• Importance of thyroid therapy: Maintaining proper thyroid hormone therapy is essential during pregnancy and breastfeeding.
• Monitoring thyroid function: Monitor thyroid function both during and after pregnancy.
• Increased need for levothyroxine: You may need a higher dose of levothyroxine during pregnancy due to increased estrogen levels.
• Thyroid suppression test: Do not perform a thyroid suppression test during pregnancy or breastfeeding.
• No known fertility problems: There is no evidence that L-Thyroxine 150 Berlin-Chemie causes fertility problems in men or women.

Effects on driving and using machines:

No known effects: Since levothyroxine is identical to the natural thyroid hormone, it is not expected to affect your ability to drive or use machines.

How to take L-Thyroxine 150 Berlin-Chemie:

• Follow your doctor’s instructions: Take the medication strictly as prescribed by your doctor.
• Individualized dosage: The daily dose is determined by your doctor based on your individual needs and test results.
• Swallow whole: Swallow the tablets whole with plenty of liquid, preferably water.
• Morning on an empty stomach: Take the medication in the morning on an empty stomach, at least half an hour before breakfast.

Dosage:

• Adults: Start with 25-50 mcg of levothyroxine sodium daily. Your doctor may increase the dose every 2-4 weeks.
• Children: The dosage is based on body surface area and individual needs.

Duration of use:

• Hypothyroidism and thyroid cancer: Usually taken for life.
• Benign goiter: May be taken for months, years, or a lifetime.

What to do in case of overdose:

• Contact your doctor: Contact your doctor if you suspect an overdose.
• Symptoms of overdose: Symptoms of overdose include hyperthyroidism, acute psychosis, palpitations, heart rhythm disturbances, chest pain, muscle weakness, heat intolerance, sweating, tremors, restlessness, insomnia, diarrhea, weight loss, headache, and menstrual irregularities.

If you forget to take L-Thyroxine 150 Berlin-Chemie:

• Do not take a double dose: If you miss a dose, do not take a double dose to make up for it. Take the next dose at the usual time.

If you stop taking L-Thyroxine 150 Berlin-Chemie:

• Do not stop without consulting your doctor: Do not change, interrupt, or stop treatment without consulting your doctor.

Possible side effects:

• Intolerance to dose level and overdose: Symptoms may include palpitations, heart rhythm disturbances, chest pain, muscle weakness, heat intolerance, sweating, tremors, restlessness, insomnia, diarrhea, weight loss, headache, and menstrual irregularities.
• Hypersensitivity: Allergic reactions may include skin rashes and respiratory problems.

Reporting side effects:

• Tell your doctor: Report any side effects you experience to your doctor or pharmacist.

Storage:

• Keep out of reach of children: Store L-Thyroxine 150 Berlin-Chemie out of reach of children.
• Store at a cool temperature: Store at a temperature not exceeding 25°C.
• Do not use after the expiry date: Do not use the medication after the expiry date stated on the blister and carton.

Composition:

• Active ingredient: Levothyroxine sodium
• Other components: Calcium hydrogen phosphate dihydrate, microcrystalline cellulose, sodium starch glycolate (type A), dextrin

Appearance:

• Round, slightly convex tablets: Almost white to slightly beige, with a notch for dividing on one side and embossed “150” on the other.

Packaging:

• Aluminum-aluminum blister: Contains 25 tablets per blister.
• One original package: Contains 100 tablets (4 blisters of 25 tablets) and leaflet.

Release conditions:

• Prescription only: L-Thyroxine 150 Berlin-Chemie is available only by prescription.

Price:

• Varies by pharmacy: The price of L-Thyroxine 150 Berlin-Chemie may vary depending on the pharmacy.

Instruction for use:

• Read carefully: Read the full instruction for use for detailed information on how to take L-Thyroxine 150 Berlin-Chemie correctly.

Remember, this information is for general knowledge and should not be considered a substitute for professional medical advice. Always consult your doctor for personalized medical guidance and treatment plans.