Diclofenac tablets p/o 25mg №10×3

Adverse reactions are classified according to the frequency of occurrence: often (?1/100, <1/10), infrequently ((?1/1000, <1/100), rarely (?1/10000, <1/1000), very rare ( <1/10000), including single messages. From the blood and lymphatic system: very rarely – thrombocytopenia, leukopenia, hemolytic anemia, aplastic anemia, agranulocytosis. From the immune system: rarely – hypersensitivity reactions, anaphylactic reactions, including arterial hypotension and anaphylactic shock very rarely – angioedema (including swelling of the face) Mental disorders: very rarely – disorientation, depression, insomnia, nightmares, irritability, psychotic disorders From the nervous system: often – headache, dizziness, rarely – drowsiness; very rarely – paresthesia, memory impairment, convulsions, anxiety, tremor, aseptic meningitis, taste disorders, cerebrovascular accident.On the part of the organs of vision: very rarely – visual disturbances, for blurred vision, diplopia. On the part of the hearing organs: often – vertigo; very rarely – ringing in the ears, hearing disorders. From the side of the cardiovascular system: very rarely – palpitations, chest pain, heart failure, myocardial infarction, arterial hypertension, vasculitis. On the part of the respiratory system: rarely – asthma (including shortness of breath), bronchospasm; very rarely – pneumonitis. From the gastrointestinal tract: often – nausea, vomiting, diarrhea, dyspepsia, abdominal pain, flatulence, anorexia; rarely – gastritis, gastrointestinal bleeding, vomiting with blood, hemorrhagic diarrhea, melena, stomach or intestinal ulcer (with / without bleeding or perforation); very rarely – colitis (including hemorrhagic colitis and exacerbation of ulcerative colitis or Crohn's disease), constipation, stomatitis, glossitis, esophageal disorders, diaphragm-like intestinal strictures, pancreatitis. From the hepatobiliary system: often – an increased level of transaminases; rarely – fulminant hepatitis, liver necrosis, liver failure. On the part of the skin and subcutaneous tissue: often – a rash; rarely – urticaria; very rarely – bullous rash, eczema, erythema, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), exfoliative dermatitis, hair loss, photosensitivity reactions, purpura, allergic purpura, scabies. From the urinary system: very rarely – acute renal failure, hematuria, proteinuria, nephrotic syndrome, interstitial nephritis, renal papillary necrosis. Clinical studies and epidemiological data suggest that Diclofenac, especially at high doses (150 mg per day) and for a long time, may be associated with a slight increase in the risk of arterial thrombosis (eg, myocardial infarction or stroke).