Depantol vaginal suppositories №5х2

Name:
Depantol supp. No. 10
Description:
Suppositories of white or white color with a grayish or yellowish tint, torpedo-shaped. Marbling is allowed. The main active ingredient Dexpanthenol + chlorhexidine Release form suppositories Pharmacological propertiesPharmacodynamicsDepantol® is a combined topical preparation that has a regenerating, antiseptic, metabolic effect. Chlorhexidine, which is part of the drug, is active against gram-positive and gram-negative bacteria: Treponema pallidum, Chlamidia spp., (Jreaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis, Escherichia coli, Staphylococcus spp. (Trichomonas vaginalis). Some strains of Pseudomonas spp., Proteys spp. are slightly sensitive to the drug, acid-resistant forms of bacteria, bacterial spores are resistant. Chlorexidine is moderately active against mycobacteria, dermatophytes and fungi. Dexpanthenol, which is part of the drug, stimulates the regeneration of mucous membranes, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers.The active components of Depantol® (vaginal suppositories) – chlorhexidine and dexpanthenol – in the applied concentrations do not have a significant inhibitory effect on the normal microflora of the vagina.Depantol® retains activity (although somewhat reduced ) in the presence of blood, pus. Pharmacokinetics Not described. Indications for use Treatment of acute and chronic vaginitis; endo / exocervicitis, including those complicated by ectopia of the epithelium of the cervix. Treatment of true erosions of the cervix of a specific etiology (as part of complex therapy). The drug is used to improve the regeneration of the mucous membrane of the vagina and cervix after destructive methods of treatment (diathermocoagulation, cryodestruction, laser destruction), in the postoperative, postpartum periods. Dosage and administration Apply intravaginally. Before use, the suppository is released from the contour packaging. Enter 1 suppository 2 times a day for 7-10 days. If necessary, it is possible to extend the course of treatment up to 20 days. Use during pregnancy and lactation Special clinical studies on the use of Depantol® in pregnant women and during breastfeeding have not been conducted. Studies in laboratory animals have not demonstrated harmful effects of dexpanthenol and chlorhexidine on pregnancy, fetal development, childbirth or the postpartum period. Use during pregnancy and lactation is permissible in the case when the expected benefit outweighs the possible risk. Precautions Use in pediatric practice There are no data on the use of the drug in children. Use in elderly patients (over 65 years) There are no data on the use of the drug in elderly patients. Use in patients with impaired renal function There are no data on the use of the drug in patients with impaired renal function. Use in patients with impaired liver function There are no data on the use of the drug in patients with impaired liver function. Influence on the ability to drive vehicles or other mechanisms Does not affect. Contraindications Hypersensitivity to the components of the drug. One suppository contains: active ingredients: dexpanthenol – 100 mg, chlorhexidine bigluconate – 16 mg (in the form of chlorhexidine bigluconate solution 20% – 85.2 mg); excipients: a mixture of macrogols: macrogol 400 – 2%, macrogol 1500 – 98% – 2814.8 mg. Overdose Information on cases of overdose of the drug Depantol® vaginal suppositories have not been reported. Interaction with other drugs Depantol® is incompatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally. Side effects The frequency of side effects is classified according to the recommendations of the World Health Organization: very often -? 10/100 often – from ? 1/100 to < 1/10 sometimes - ? 1/1000 to <1/100 rare - from ? 1/10000 to < 1/1000 very rare - < 1/10000. Rarely: in rare cases, an intolerance reaction manifests itself as a local allergic reaction. Very rare: topical application of chlorhexidine may lead to generalized allergic reactions. Sometimes: short-term burning and / or itching in the vagina. In the event of adverse reactions, including those not listed in this leaflet, you should stop using the drug and consult a doctor. Storage conditions In a place protected from light, at a temperature not exceeding 20 ° C. In a place inaccessible to children. Buy Depantol vaginal suppositories No. 5x2 Price for Depantol vaginal suppositories No. 5x2