Argosulfan cream 20mg/g 40g №1

Argosulfan Cream 20mg/g 40g: Effective Wound Healing & Infection Control

Discover the Power of Argosulfan Cream for Effective Wound Care

Argosulfan Cream 20mg/g is a topical antimicrobial agent that provides effective treatment for a range of wound infections, including burns, bedsores, and leg ulcers. This high-quality cream, available in a 40g tube, offers a convenient and reliable solution for promoting wound healing and controlling infection.

Key Features & Benefits:

• Active Ingredient: Silver sulfathiazole, a potent antimicrobial agent that effectively combats bacterial infections.
• Wide Range of Applications: Treats skin burns (all degrees, including radiation), bedsores, and trophic ulcers of the legs.
• Easy Application: Apply topically, both openly and with occlusive dressings, for complete wound coverage.
• Proven Efficacy: Demonstrated effectiveness in promoting wound healing and preventing infection.

How It Works:

Argosulfan Cream works by inhibiting bacterial growth, preventing further infection and promoting a healthy healing environment. Its unique formula allows for effective penetration into the wound, ensuring optimal therapeutic action.

Safe and Effective for Most Patients:

While Argosulfan is generally safe and effective, it’s important to consult with your healthcare professional for personalized guidance and to ensure suitability for your specific situation.

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Explore the detailed information below for comprehensive insights into Argosulfan Cream’s usage, safety, and potential side effects.

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Product Description:

Argosulfan Cream 20mg/g is a white or off-white, homogeneous soft cream. It contains silver sulfathiazole as the active ingredient.

Indications for Use:

Argosulfan is used topically to treat wound infections, including:

• Skin burns of all degrees (including radiation)
• Bedsores (pressure ulcers)
• Trophic ulcers of the legs (venous or arterial ulcers)

Dosage and Administration:

• External use only.
• Cleansing and Surgical Treatment: Before applying Argosulfan, cleanse and surgically treat the wound under sterile conditions.
• Application: Apply a layer of cream 2-3 mm thick to the wound 2-3 times daily. Ensure complete wound coverage.
• Occlusive Dressings: While optional, occlusive dressings can be used.
• Duration: Continue application until the wound is completely healed or prepared for skin grafting.
• Infected Wounds: Exudate may appear in infected wounds.
• Wound Cleansing: Wash the wound with 0.1% chlorhexidine solution, 3% boric acid solution, or other antiseptic before applying the cream.

Special Considerations:

• Children and Adolescents: Not for use in premature infants, newborns, or infants under 2 months due to kernicterus risk. Dose adjustment is not necessary for older children.
• Renal Insufficiency: Use with caution. Monitor serum sulfonamide concentrations in patients with severe renal impairment.
• Hepatic Insufficiency: Use with caution due to lack of clinical trials in patients with hepatic insufficiency.
• Pregnancy and Lactation: Avoid use during pregnancy and breastfeeding, except in situations where the potential benefit to the mother outweighs the risk to the fetus or infant.

Precautions:

• Cross-Hypersensitivity: Possible cross-sensitivity to sulfonylurea derivatives, benzothiazine, and para-aminobenzoic acid. Thorough allergic history is essential, especially related to sulfonamides.
• Eye and Mucous Membrane Contact: Avoid contact. Wash thoroughly with water if contact occurs.
• Shock and Burns: Use with caution in patients in shock after extensive burns or with burns that make maintaining contact difficult.
• Liver and Kidney Impairment: Potential for drug accumulation and systemic adverse reactions. Monitor liver and kidney function.
• Long-Term Use: Avoid prolonged use (over 60 days) to minimize the risk of systemic effects. Monitor blood serum sulfathiazole levels.
• Excipients: Cetostearyl alcohol may cause local reactions (contact dermatitis). Methyl parahydroxybenzoate and propyl parahydroxybenzoate may cause allergic reactions.

Drug Interactions:

• Folic Acid and Para-Aminobenzoic Acid Derivatives: May weaken the antibacterial effect of silver sulfathiazole.
• Other Topical Drugs: Not recommended for simultaneous use to avoid potential interactions.

Contraindications:

• Allergy: Allergy to sulfathiazole, other sulfonamides, or any component of the cream.
• Breastfeeding: Not for use in breastfeeding women.
• Premature Infants, Newborns, Infants under 2 Months: Risk of kernicterus.
• Glucose-6-Phosphate Dehydrogenase Deficiency: Risk of hemolytic anemia.

Overdose:

No cases of overdose have been reported. Absorption of silver sulfathiazole through damaged skin is possible.

Side Effects:

• Local Reactions: Skin irritation, burning, itching, erythema at the application site.
• Systemic Side Effects: Possible with prolonged use, including kidney and liver damage, hematological disorders (agranulocytosis, anemia), hypersensitivity reactions (Stevens-Johnson syndrome, exfoliative dermatitis).

Storage Conditions:

• Store at a temperature not exceeding 25°C.
• Do not freeze.
• Keep out of reach of children.

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This information is for general knowledge purposes only and does not substitute professional medical advice. Consult with your healthcare provider for personalized guidance and to ensure the safety and suitability of Argosulfan Cream for your specific needs.