Anuzol rectal suppositories №5х2

Name:
Anuzol supp. rect. in a box No. 5×2
Description:
Torpedo-shaped suppositories of greenish-yellow or greenish-yellow with a brownish tint or light brown color with a xeroform odor. The appearance of white plaque on the surface of the suppository is allowed. Release form suppositories Pharmacological properties Pharmacodynamics Antihemorrhoidal combined agent. Anuzol has antispasmodic, anti-inflammatory, antiseptic, analgesic, local anti-inflammatory, astringent and drying effects. Pharmacokinetics Not described. Indications for useHemorrhoids, anal fissures in adults. Dosing and Administration Rectally. 1 suppository 1-3 times a day after a cleansing enema or spontaneous bowel movements. The maximum daily dose of the drug is 7 suppositories. The duration of treatment is determined by the doctor, taking into account the course and severity of the disease, the therapeutic effect achieved. Use during pregnancy and lactation There are no data on the use of the drug in pregnant women. Anuzole should not be used during pregnancy. If necessary, the use of the drug Anuzol during lactation should stop breastfeeding. Precautions Use with caution in patients with prostatic hyperplasia without urinary tract obstruction, Down’s syndrome, cerebral palsy; with reflux esophagitis, hernia of the esophageal opening of the diaphragm, combined with reflux esophagitis, ulcerative colitis, megacolon, xerostomia; elderly or debilitated patients; in chronic lung diseases without reversible obstruction, in chronic lung diseases occurring with low production of thick sputum, which is difficult to separate, especially in debilitated patients; with autonomic (autonomous) neuropathy. Use in children The use of the drug is contraindicated in children (under 18 years of age). Influence on the ability to drive vehicles and work with mechanisms Given the possibility of such adverse reactions as dizziness, hallucinations, disturbance of accommodation, when using the drug, you should refrain from driving vehicles or working with mechanisms. Interaction with other drugs When using the drug with monoamine oxidase inhibitors, cardiac arrhythmia occurs; with quinidine, novocainamide – synergism of the anticholinergic effect; with preparations of lily of the valley, tannin, a physical and chemical interaction is observed, leading to a mutual weakening of the effects. Anuzole reduces the duration and depth of the effects of narcotic drugs, weakens the analgesic effect of opiates. With simultaneous use with diphenhydramine or diprazine, the effect of atropine is enhanced; with nitrates, haloperidol, corticosteroids for systemic use, the likelihood of an increase in intraocular pressure increases; with sertraline – the depressive effect of both drugs is enhanced; with spironolactone, minoxidil – the effect of spironolactone and minoxidil is reduced; with penicillins – the effect of both drugs is enhanced; with nizatidine – the effect of nizatidine is enhanced; with ketoconazole – the absorption of ketoconazole decreases; with ascorbic acid and attapulgite – the action of Anuzol decreases; with pilocarpine – the effect of pilocarpine in the treatment of glaucoma is reduced; with oxprenolone – the antihypertensive effect of the drug is reduced. Under the influence of guanethidine, a decrease in the hyposecretory effect of the drug is possible. Weakens the action of M-cholinomimetics and anticholinesterase agents. With simultaneous use with sulfanilamide drugs, the risk of kidney damage increases, with drugs containing potassium, the formation of intestinal ulcers is possible, with non-steroidal anti-inflammatory drugs, the risk of gastric ulcers and bleeding. The action of Anuzole may be enhanced with the simultaneous use of other drugs with an antimuscarinic effect: M-anticholinergics, antiparkinsonian drugs (amantadine), antispasmodics, some antihistamines, drugs of the butyrophenone group, phenothiazines, quinidine, tricyclic antidepressants, non-selective monoamine reuptake inhibitors. Inhibition of peristalsis under the action of Anuzol can lead to a change in the absorption of other drugs. If you are currently using/taking other medicines, tell your doctor. Contraindications Hypersensitivity to the components of the drug. Atrial fibrillation, tachycardia, chronic heart failure, coronary heart disease, mitral stenosis, severe arterial hypertension. Acute bleeding. thyrotoxicosis. Hyperthermic syndrome, diseases of the gastrointestinal tract, accompanied by obstruction (achalasia of the esophagus, pyloric stenosis, intestinal atony). Glaucoma. Liver and kidney failure. Myasthenia. Prostate hyperplasia in the stage of decompensation, acute urinary retention. Children’s age up to 18 years. Composition One suppository contains: active ingredients: bismuth tribromophenolate and bismuth oxide complex (xeroform) – 0.10 g, belladonna leaf extract (thick belladonna extract), 5-9: 1, extractant – ethanol 70%, with the content of the total belladonna alkaloids in terms of for hyoscyamine 1.5% – 0.02 g, zinc sulfate heptahydrate – 0.05 g; excipients: glycerol (distilled glycerin), purified water, distilled monoglycerides, solid fat (vitepsol (brands H 15, W 35) or supposir (brands NA 15, NAS 50)) – until a suppository weighing 2.25 g is obtained. increased manifestation of adverse reactions, nausea, vomiting, lowering blood pressure, agitation, tremor, convulsions, insomnia, drowsiness, hallucinations, irritability, depression of the central nervous system, depression of the activity of the respiratory and vasomotor centers, urinary retention, hyperthermia. Treatment: gastric lavage, parenteral administration of cholinomimetics and anticholinesterase agents. With hyperthermia, wet rubdowns and antipyretics are indicated, with arousal – the introduction of sodium thiopental or sodium hydroxybutyrate intravenously, with mydriasis – locally in the form of eye drops phosphacol, physostigmine, pilocarpine. In the event of an attack of glaucoma, a 1% solution of pilocarpine is instilled into the conjunctival sac, 2 drops every hour, and 1 ml of a 0.05% solution of prozerin is injected subcutaneously 3-4 times a day. In case of overdose, stop using the drug immediately and consult a doctor (take the package of the drug with you). Side effects Disorders of the gastrointestinal tract: dry mouth, thirst, impaired taste sensations, dysphagia, decreased intestinal motility to atony, decreased tone of the biliary tract and gallbladder, constipation, diarrhea. Renal and urinary disorders: Difficulty and urinary retention. Cardiac disorders: tachycardia, palpitations, arrhythmia, including extrasystole, myocardial ischemia. Vascular disorders: flushing of the face, sensation of hot flashes. Nervous system disorders: headache, dizziness, nervousness, insomnia. On the part of the organ of vision: dilated pupils, photophobia, accommodation paralysis, increased intraocular pressure, temporary visual disturbances. Respiratory, thoracic and mediastinal disorders: formation of viscous sputum that is difficult to cough up. Skin and subcutaneous tissue disorders: skin rashes, urticaria, exfoliative dermatitis. Immune system disorders: anaphylactic reactions, including anaphylactic shock. Others: decreased sweating, dry skin, dysarthria, burning sensation in the anus. In the event of adverse reactions, including those not listed in this leaflet, stop using the drug and consult a doctor. Storage conditions In a place protected from light at a temperature not exceeding 25 ° C. Keep out of the reach of children. Buy Anuzole rectal suppositories No. 5×2 Price for Anuzole rectal suppositories No. 5×2